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Top Luxury Charleston Hotels

The Charleston Place

205 Meeting Street Charleston SC

8 min walk from Medical University of South Carolina

Pamper yourself with a luxury stay at The Charleston Place, where you can enjoy amenities like premium mattresses, rainfall showers, and more. Deluxe amenities ...

9.6/10 Exceptional! (1,005 reviews)

Fine

Reviewed on May 11, 2026

Market Pavilion Hotel

225 East Bay Street Charleston SC

10 min walk from Medical University of South Carolina

Market Pavilion Hotel is a Charleston luxury 4.5-star boutique property where you can treat yourself to massage services, Frette Italian sheets, and more. The ...

9.4/10 Exceptional! (1,004 reviews)

Friendly and attentive Beautiful hotel. Close to everything

Reviewed on May 4, 2026

Planters Inn

112 N Market St Charleston SC

9 min walk from Medical University of South Carolina

Planters Inn is one of the Charleston luxury 4.5-star boutique properties where you can pamper yourself with Frette Italian sheets, pillowtop beds, and more. ...

9.6/10 Exceptional! (1,014 reviews)

Wonderful historic hotel — perfect location, excellent staff.

Reviewed on May 12, 2026

See all 5,043 properties in Charleston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.