Missouri Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ₩234,741 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Luxury Missouri Hotels
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
The price is ₩223,106 per night from Dec 7 to Dec 8
₩223,106
₩285,067 total
Dec 7 - Dec 8
includes taxes & fees
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
8.4/10 Very Good! (1,000 reviews)
Room was nice. Enjoyed the pool view and spaciousness. Staff was friendly upon arrival and departure.
Reviewed on Dec 2, 2025
Four Seasons Hotel St Louis
999 North Second Street St. Louis MO
The price is ₩608,539 per night from Jan 1 to Jan 2
₩608,539
₩711,558 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Be treated to deluxe lodging at Four Seasons Hotel St Louis, where you'll find deep soaking bathtubs and a champagne service. Notable amenities include a spa, ...
9.4/10 Exceptional! (1,006 reviews)
Clean room. Great staff.
Reviewed on Nov 29, 2025
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
The price is ₩145,247 per night from Dec 14 to Dec 15
₩145,247
₩169,557 total
Dec 14 - Dec 15
includes taxes & fees
Choose luxury at Clayton Plaza Hotel & Extended Stay, where you can enjoy amenities like pillowtop beds, HDTVs, and more. Notable amenities include a heated ...
8.8/10 Excellent! (3,023 reviews)
This hotel was great, quiet area , yet located close enough to things
Reviewed on Dec 2, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Vacation Ideas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
