Photo by Visit Mississippi Gulf Coast

Plan, book, travel with confidence
Better together
Save up to ₩234,741 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Mississippi Gulf Coast Hotels

Beau Rivage

875 Beach Blvd Biloxi MS

1 min walk from Beau Rivage Casino

Treat yourself to a decadent stay at Beau Rivage, where you'll find deep soaking bathtubs and pillowtop beds. Notable amenities include a casino, a spa, and ...

9.2/10 Wonderful! (1,423 reviews)

Great room very comfortable.

Reviewed on Jan 17, 2026

Margaritaville Resort Biloxi

195 Beach Blvd Biloxi MS

21 min walk from Beau Rivage Casino

Margaritaville Resort Biloxi is a Biloxi luxury 3.5-star beach property where you can treat yourself to pillowtop beds, flat-screen TVs, and more. Notable amenities ...

8.6/10 Excellent! (5,576 reviews)

Very nice and enjoyed our stay! Wish we had more time to see all amenities they offered

Reviewed on Jan 22, 2026

White House Hotel

1230 Beach Blvd Biloxi MS

14 min walk from Beau Rivage Casino

White House Hotel is one of the Biloxi luxury 3-star beach properties where you can treat yourself to plush bedding, premium channels, and more. Deluxe amenities ...

8.8/10 Excellent! (1,007 reviews)

Cleanliness and all the staff aimed to please.

Reviewed on Jan 19, 2026

See all 3,031 properties in Mississippi Gulf Coast

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.