Plan, book, travel with confidence
Better together
Save up to ₩234,741 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Eastern South Dakota Hotels

Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport

3101 W Russell St Sioux Falls SD

25 min walk from Denny Sanford Premier Center

Be treated to luxurious accommodations at Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport, where you can enjoy amenities like hydromassage showers, ...

6.8/10 (1,006 reviews)

Great stay. Nice hotel great staff. Thanks!

Reviewed on Feb 23, 2026

Econo Lodge Sioux Falls Empire Mall

3500 Gateway Boulevard Sioux Falls SD

9 min drive from Denny Sanford Premier Center

Stay in the lap of luxury at Econo Lodge Sioux Falls Empire Mall, where you can enjoy amenities like premium channels, flat-screen TVs, and more.

7/10 Good! (442 reviews)

Economy hotel, no thrills, but it's nice

Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean.

Reviewed on Oct 18, 2022

My Place Hotel - Sioux Falls, SD

3005 S. Carolyn Ave Sioux Falls SD

8 min drive from Denny Sanford Premier Center

Go for a luxurious stay at My Place Hotel - Sioux Falls, SD, where you can enjoy amenities like pillowtop beds, premium channels, and more.

8.6/10 Excellent! (1,005 reviews)

This is a very clean place. Nice amenities conveniently located to everything you’d need,

Reviewed on Feb 21, 2026

See all 964 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.