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Top Luxury Southwest Florida Hotels

Wyvern Hotel, an Ascend Collection Hotel

101 E Retta Esplanade Punta Gorda FL

1 hour drive from Siesta Key Beach

Stay in the lap of luxury at Wyvern Hotel, an Ascend Collection Hotel, where you can enjoy amenities like Champagne service, plush bedding, and more. Deluxe ...

Signia Hilton Naples Grande Beach Resort

475 Seagate Drive Naples FL

3 hours drive from Siesta Key Beach

Be treated to a grand stay at Signia Hilton Naples Grande Beach Resort, where you'll find deep soaking bathtubs and premium bedding. Deluxe amenities at this ...

The Ritz-Carlton, Sarasota

1111 Ritz Carlton Dr Sarasota FL

12 min drive from Siesta Key Beach

Stay in the lap of luxury at The Ritz-Carlton, Sarasota, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. The 2 outdoor pools, ...

9.2/10 Wonderful! (1,020 reviews)

"Very well maintained property. Staff very kind and professional. Our room was spacious and well appointed . The beds were somewhat comfortable , they need better pillows. Also, they need more dining options. Overall, nice property."

Reviewed on Nov 9, 2026

See all 47,961 properties in Southwest Florida

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.