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Top Adventure Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...

8.4/10 Very Good! (2,012 reviews)

The only thing was the mattress was too hard. Very uncomfortable.

Reviewed on Apr 22, 2026

Country Inn & Suites by Radisson, Rochester, MN

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (1,000 reviews)

Safe, clean, friendly and great price.

Reviewed on Apr 17, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG

220 S Broadway Rochester MN

6 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...

8.8/10 Excellent! (1,000 reviews)

Good stay

Reviewed on Apr 22, 2026

See all 945 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.