Photo by Southernmost Illinois Tourism Bureau

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Top Kid friendly Southwest Illinois Hotels

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL

43 min drive from Southern Illinois University

Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

8.6/10 Excellent! (1,003 reviews)

Clean and comfortable, close to restaurants.

Reviewed on Mar 4, 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

2 hours drive from Southern Illinois University

Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

9.6/10 Exceptional! (1,666 reviews)

The Drury Inn is always a pleasant stay. Breathed is always delicious! I always appreciate tte complimentary drinks and food in the evening too.

Reviewed on Mar 9, 2026

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL

3 hours drive from Southern Illinois University

Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

6.6/10 (115 reviews)

I was surprised at how filthy the room and sheets were. I ended up checking out early and going somewhere else.

Reviewed on Mar 6, 2026

See all 744 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.