Photo by Matt Russell

Plan, book, travel with confidence
Better together
Save up to ₩234,741 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Northwest Alabama Hotels

The ColdWater Inn

712 Hwy 72 W Tuscumbia AL

17 min drive from University of North Alabama

Be treated to luxurious accommodations at The ColdWater Inn, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. Deluxe amenities ...

8.8/10 Excellent! (643 reviews)

Unique hotel for a great price. Unique furnishings and comfortable accommodations.

Reviewed on Dec 5, 2025

Clarion Inn Sheffield Muscle Shoals

4900 Hatch Blvd Sheffield AL

8 min drive from University of North Alabama

Pamper yourself with a luxe vacation at Clarion Inn Sheffield Muscle Shoals. Popular amenities include a nightclub, an outdoor pool, and a restaurant.

7.2/10 Good! (962 reviews)

Parking was fast and easy

Reviewed on Nov 29, 2025

Baymont by Wyndham Florence/Muscle Shoals

115 Ana Drive Florence AL

9 min drive from University of North Alabama

Pamper yourself with an extravagant stay at Baymont by Wyndham Florence/Muscle Shoals, where you'll find deep soaking bathtubs and pillowtop beds. The outdoor ...

7.2/10 Good! (892 reviews)

Clean and everyone was nice

Reviewed on Dec 2, 2025

See all 747 properties in Northwest Alabama

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.