Eastern Tennessee Luxury Vacations

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Top Luxury Eastern Tennessee Hotels

Carnegie Hotel & Spa
Carnegie Hotel & Spa
4 out of 5
1216 W State Of Franklin Rd, Johnson City, TN
  • 2 hours drive from Great Smoky Mountains National Park
Treat yourself to upscale accommodations at Carnegie Hotel & Spa, where you'll enjoy amenities like premium channels and more. Notable amenities include a spa, ...
9.6/10 Exceptional! (1,200 reviews)
"Very nice, everything we expected and more"

Reviewed on Jul 2, 2025

Carnegie Hotel & Spa
THE TENNESSEAN Hotel
THE TENNESSEAN Hotel
4 out of 5
531 Henley Street, Knoxville, TN
  • 55 min drive from Great Smoky Mountains National Park
Treat yourself to a luxury stay at THE TENNESSEAN Hotel, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. The restaurant, fitness ...
9.4/10 Exceptional! (1,002 reviews)
"Will visit again"

Reviewed on Jul 2, 2025

THE TENNESSEAN Hotel
The Read House Hotel
The Read House Hotel
4 out of 5
107 West Martin Luther King Blvd, Chattanooga, TN
  • 4 hours drive from Great Smoky Mountains National Park
Go for a luxurious stay at The Read House Hotel, where you can enjoy amenities like Champagne service, plush bedding, and more. The indoor pool, restaurant, ...
9.4/10 Exceptional! (2,040 reviews)
"Everything was good"

Reviewed on Jun 30, 2025

The Read House Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.