
Southeast Illinois Pet-friendly Vacations
Book a Pet-friendly Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
- Plan, book, travel with confidence
Better together
Save up to ₩234,741 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Pet-friendly Southeast Illinois Hotels

La Quinta Inn & Suites by Wyndham Effingham
1103 Avenue Of Mid America, Effingham, IL
This pet-friendly hotel welcomes dogs and cats (fees apply).
9.2/10 Wonderful! (1,002 reviews)
"Very clean hotel with friendly staff!"
Reviewed on Aug 22, 2025

Rodeway Inn Effingham North
1400 Thelma Keller Ave, Effingham, IL
Stay at this motel in Effingham. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,000 reviews)
"Nice hotel"
Reviewed on Aug 17, 2025

Quality Inn Effingham North
1304 W Evergreen Drive, Effingham, IL
Stay at this hotel in Effingham. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.2/10 Very Good! (923 reviews)
"The staff is super nice!"
Reviewed on Aug 23, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.