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Find hotels near Calle 50, Panama City from ₩64,874

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Dec 18 - Dec 19
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Dec 19 - Dec 20
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Dec 19 - Dec 21
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Dec 26 - Dec 28

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Our top choices for Calle 50 hotels

Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 1.2 km from Calle 50
10.0 out of 10, Exceptional, (125)
"Great hotel fair price"
United States
Santiago
The price is ₩199,375
₩219,312 total
includes taxes & fees
Dec 20 - Dec 21
Hyatt Regency Panama City
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (1015)
" Clean rooms friendly staff"
United States
Karen
The Executive Hotel
Outdoor pool, sun loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (4687)
"Awesome great place to stay "
United States
Herbert
The price is ₩188,937
₩207,831 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Riu Plaza Panama
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2137)
"Great location, friendly staff, excellent views and the best breakfast around."
Canada
Gregory
The price is ₩159,426
₩175,376 total
includes taxes & fees
Dec 27 - Dec 28
Plaza Paitilla Inn Hotel
Exterior
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco, 0.4 km from Calle 50
9.0 out of 10, Wonderful, (1001)
"Staff was very helpful. Great location."
United States
John
The price is ₩136,603
₩150,264 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Courtyard by Marriott Panama Multiplaza Mall
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (1006)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is ₩296,256
₩325,882 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Bristol Panama, a Registry Collection Hotel
Front of property
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1023)
"Great service, big room, solid breakfasts.. all at good price."
Canada
Nicholas
The price is ₩156,581
₩172,239 total
includes taxes & fees
Dec 21 - Dec 22
Novotel Panama City
Front of property - evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1596)
"Room was awesome beyond our expectations it's definitely will be shared with others from Belize that Principe is the best so far I have stayed in Panama City 🌆"
United States
Robert
The price is ₩81,460
₩89,606 total
includes taxes & fees
Dec 21 - Dec 22
Principe Hotel and Suites
Exterior
Hotel Milan

Hotel Milan

Hotel Milan
3.0 star property
El Cangrejo, 1.3 km from Calle 50
9.0 out of 10, Wonderful, (427)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is ₩58,976
₩64,874 total
includes taxes & fees
Dec 21 - Dec 22
Hotel Milan
View from property
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1015)
"I loved my stay! "
United States
Jenniffer Gonzalez De La
The price is ₩257,887
₩283,674 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Las Americas Golden Tower Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 1.4 km from Calle 50
9.0 out of 10, Wonderful, (626)
"Very great hotel and service "
United States
Prakash
The price is ₩108,297
₩215,650 total
includes taxes & fees
Dec 26 - Dec 27
Waymore Hotel Spa & Casino
Terrace/patio
Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel
2.0 star property
Bella Vista, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (9)
"The manager was very nice. Close to some good restaurants."
United States
Brooke
Hostal Familiar Carmencita - Hostel
Reception
Hotel Coral Suites

Hotel Coral Suites

Hotel Coral Suites
3.5 star property
El Cangrejo, 1.2 km from Calle 50
9.0 out of 10, Wonderful, (1003)
"The entire staff were amazing! Everyone exceeded my expectations including the front desk, cleaning team, bellhop and the restaurant next door was a plus. "
United States
Conchita
The price is ₩98,358
₩108,194 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Coral Suites
Outdoor pool
MARINN PLACE Financial District

MARINN PLACE Financial District

MARINN PLACE Financial District
3.5 star property
Campo Alegre, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (299)
"Second stay, very nice"
Canada
Xiaozhi
The price is ₩371,549
₩408,704 total
includes taxes & fees
Jan 17 - Jan 18, 2026
MARINN PLACE Financial District
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers
Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 1 km from Calle 50
9.0 out of 10, Wonderful, (538)
"It's location is close to everything. "
United States
Sharon
The price is ₩224,703
₩247,173 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Residence Inn by Marriott Panama City
Terrace/patio
Toscana Inn

Toscana Inn

Toscana Inn
3.5 star property
El Cangrejo, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (727)
"Friendly staff clean room’s walk able to shops"
United States
Noris
Toscana Inn
Meeting facility
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 0.6 km from Calle 50
8.8 out of 10, Excellent, (1004)
"Everything was clean and the staff was very cooperative."
United States
Deangelo
The price is ₩234,430
₩257,873 total
includes taxes & fees
Dec 21 - Dec 22
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Outdoor pool, pool umbrellas, sun loungers
Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (984)
"Great view Great buffet Breakfast was excellent "
Canada
Robert
The price is ₩130,051
₩143,056 total
includes taxes & fees
Dec 23 - Dec 24
Best Western Plus Panama Zen Hotel
Exterior
Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Campo Alegre, 0.7 km from Calle 50
8.8 out of 10, Excellent, (1004)
"Clean room , friendly staff "
United States
Junique
The price is ₩118,148
₩138,085 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Holiday Inn Panama Distrito Financiero by IHG
Lobby sitting area
San Francisco by Wynwood House

San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (56)
"Clean and walkable location"
United States
Tamera
The price is ₩213,996
₩272,317 total
includes taxes & fees
Dec 20 - Dec 21
San Francisco by Wynwood House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Calle 50 Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Great room and bathroom! Everyone was really friendly. "
Debbie
Posted 2 days ago
Hotel Riu Plaza Panama

Hotels near other Calle 50 attractions

You can find Gucci at Luxury Avenue at Multiplaza Mall in Panama City. #LuxuryShopping #LifeatExpedia #PanamaCity
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

4.4/5 (1,590 reviews)
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
See properties
Nice building, highlight on Panama's skyline.
Photo by My World
Open Photo by My World

Soho City Center

You can browse for the perfect souvenirs at Soho City Center during your stay in Panama City. Discover the area's casinos, or seek out its local tours.
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Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 471 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Calle 50?
Adjacent to Calle 50, Courtyard by Marriott Panama Multiplaza Mall is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good options close by include Hotel Riu Plaza Panama and Las Americas Golden Tower Panama.
How many hotels will I be able to find near Calle 50?
Expedia has 471 hotels and other accommodations within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then use the "fully refundable" filter to view the best deals available near Calle 50.
Where can I learn more about changing or cancelling my trip in the area near Calle 50?
To find more details about updating your stay near Calle 50 or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo, and Colonial Religious Art Museum. Iglesia del Carmen, Panama Viejo, and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Theater Circle, and Anita Villalaz Theater.
How can I get to Calle 50?
Local metro stations include Iglesia del Carmen Station and Vía Argentina. If you'd like to explore around the surrounding area, you may want a car rental for your journey.