Find Resorts & Hotels with Spas in Cincinnati, OH

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Check availability on Cincinnati Resorts & Hotels with Spas

Our top choices for Cincinnati hotels with a spa

Body treatments, hydrotherapy, hot stone massages, deep-tissue massages
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

4.5 star property
Downtown Cincinnati
8.6 out of 10, Excellent, (1007)
"Very clean rooms, great bar, friendly staff."
United States
Theodore
The price is ₩210,999
₩259,066 total
includes taxes & fees
Jan 2 - Jan 3, 2026
21c Museum Hotel Cincinnati
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cincinnati Hotel Reviews

Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

10/10 Excellent
"Room was clean the atmosphere was amazing The food was great I would highly recommend it"
Michelle 1-night trip
Posted 2 days ago
Hilton Cincinnati Netherland Plaza

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Frequently asked questions

Looking to vacation at a spa hotel in Cincinnati?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers like the live music scene and theater scene in Cincinnati so get ready for a cultural tour. Be sure to pay a visit to the museums during your stay. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Cincinnati?
21c Museum Hotel Cincinnati is a top luxury spa hotel featuring a 24-hour fitness center, a bar, and a restaurant. Enjoy a facial, body scrub, or Swedish massage at the onsite spa.
How many spa hotels will I find in Cincinnati?
Among Expedia's 1888 accommodation options in Cincinnati, there is 1 spa hotel.
What's there to see and do in Cincinnati?
Enjoy Cincinnati and visit Fountain Square, Aronoff Center for the Arts, and Taft Theatre. If you have extra time while you're in the area, you might want to stop by National Underground Railroad Freedom Center and Cincinnati Reds Hall of Fame and Museum.
What is a Cincinnati spa hotel?
Spa hotels in Cincinnati provide lodging and have an on-site spa which offers services like therapies and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.