A street with houses, a water tower, and a banana tree.

Des Peres, St. Louis hotel rooms at the OYO Rooms

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 10 - Sep 11
Tomorrow
Sep 11 - Sep 12
This weekend
Sep 11 - Sep 13
Next weekend
Sep 18 - Sep 20
Save an average of 15% on thousands of hotels when you're signed in

Top Des Peres Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Wonderful stay"
Kelly 1-night trip
Posted less than an hour ago
Hyatt Regency St. Louis at The Arch
Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark

10/10 Excellent
"Perfect location. Close to everything. Staff were very friendly and helpful."
Frances Gorman 2-night trip
Posted 3 hours ago
Hilton St. Louis at the Ballpark
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"Came back for the omelette bar.."
Stephen 3-night trip
Posted 4 hours ago
Clayton Plaza Hotel & Extended Stay
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"My room was very clean & the staff were very attentive to any requests that were made throughout my stay. I will always recommend ANY Hilton hotel property!"
Lisa 1-night trip
Posted 4 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent
"We love that our dogs can stay for free without any hassle. We always stay here when we’re in St. Louis. It’s convenient and clean and the staff is always very kind. The location is kind of sketchy but I have noticed that they’re cleaning it up! The square next door isn’t full of trash and drunks anymore. We’ve parked on the street several times and had no issues, but we’ve also used a nearby parking garage for about half the price of the hotel."
Krista 1-night trip
Posted 4 hours ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good
"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day and all night long (good thing I had good earplugs). Make sure to get a room away from the elevator. Also, the cable tv system is a mess. The channels don't match what the cable guide on the TV says nor what the icon in the corner of the screen says. Also, many of the channels they're supposed to have say "no signal." Not a huge deal but definitely annoying. A simple piece of paper in the room which lists the real channels would certainly help."
John 3-night trip
Posted 7 hours ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent
"Awesome loved everything"
philip 1-night trip
Posted 19 hours ago
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"My only complaint is there wasn’t a working ice machine on our floor. Other than that we had an excellent time and everything was great"
Matthew 2-night trip
Posted 23 hours ago
Ameristar Casino Resort and Spa
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

8/10 Good
"The rooms and hotel were nice."
Lauren 1-night trip
Posted 2 days ago
Renaissance St. Louis Airport Hotel

Explore a world of travel with Expedia