Top 10 Hotels in Des Peres, MO from ₩122,066 - Competitive Prices

A street with houses, a water tower, and a banana tree.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Des Peres

Pet friendly

Hot tub

Apartment

Pool

Family friendly

Cottage

Waterpark

Condo

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Des Peres hotels

A spacious lobby with multiple seating areas, a central coffee table, and artwork on the walls.

A hotel with multiple floors, a prominent 'Best Western' sign, and a parking area with several cars.

A gym with treadmills, an elliptical, and dumbbells on shelves.

A kitchen with wooden cabinets, a black countertop, and a microwave. There is a table and chairs set up for dining.

1. Best Western St. Louis-Kirkwood Route 66

Kirkwood

Sonja

₩129,142

₩151,081 total

includes taxes & fees

Oct 21 - Oct 22

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

A modern hotel lobby with a cityscape view, a reception desk, and ambient lighting.

A modern dining area with multiple tables and chairs, large windows offering a view of the outdoors, and a mix of natural and artificial lighting.

A modern hotel lobby with a seating area, a desk, and large windows offering a view of the outside.

2. La Quinta Inn & Suites by Wyndham St Louis Route 66

St. Louis

Tiffany

₩133,412

₩155,064 total

includes taxes & fees

Oct 8 - Oct 9

A bar area with a long counter displaying numerous bottles of alcohol and several empty wine glasses lined up.

A restaurant interior with wooden panel walls, hanging light fixtures, and a chalkboard menu. Tables and chairs are arranged for dining.

A modern lobby with a grey sofa, two armchairs, a round table, and a chandelier. There are two posters on the wall and a reception desk in the background.

3. Holiday Inn St Louis SW - Route 66 by IHG

St. Louis

Willie

₩158,160

₩188,104 total

includes taxes & fees

Oct 25 - Oct 26

A modern dining area with multiple tables and chairs, recessed ceiling lights, and a kitchen in the background.

A gym with treadmills, elliptical machines, and a mirrored wall.

An outdoor patio area with a fire pit, black metal chairs, and a blue umbrella.

A hotel room with two beds, a desk, and a window with a view of trees.

4. Best Western Plus Fenton

Fenton

Brian

₩132,158

₩152,627 total

includes taxes & fees

Oct 8 - Oct 9

A modern interior with hanging pendant lights, large windows, and a view of the outside.

A hotel room with a flat-screen TV, a wooden cabinet, a light-colored sofa, a matching ottoman, and a small table.

A hotel indoor pool area with a hot tub, seating, and a view of the outdoors.

A modern hotel lobby with a high ceiling, multiple hanging pendant lights, a reception desk with a Missouri US 66 sign, and large windows allowing natural light.

5. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

Dashaun

₩119,729

₩138,282 total

includes taxes & fees

Nov 1 - Nov 2

A modern lobby with a stone fireplace, blue sofas, and potted plants.

A hotel room with two beds, a desk, and a window with a city view.

A modern building with a stone facade, large windows, and a covered entrance area.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled deck.

6. Comfort Suites St. Louis - Sunset Hills

St. Louis

John

₩158,361

₩184,077 total

includes taxes & fees

Oct 14 - Oct 15

A modern hotel lobby with a high ceiling, a central seating area with sofas and a coffee table, and a flat-screen TV mounted on the wall.

A spacious lobby with a high ceiling, a flat-screen TV mounted on the wall, and a seating area with sofas and ottomans.

A hotel room with a bed, a desk with a computer, a television, a sofa, and a window with a view.

An indoor swimming pool with a hot tub, lounge chairs, and a tiled floor.

7. Drury Inn & Suites Southwest St. Louis

Valley Park

Randy

₩154,126

₩180,308 total

includes taxes & fees

Oct 25 - Oct 26

A hotel lobby with a staircase, dining area, and reception desk.

An indoor swimming pool with a tiled floor, a pool ladder, and a few chairs and tables around the pool area.

A hotel room with a large bed, a separate bathroom with a bathtub, a flat-screen TV, and a framed picture on the wall.

A coffee station with two coffee machines, a shelf with coffee cups, and a storage area with boxes and a thermos.

8. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Fenton

Donna

₩134,150

₩154,928 total

includes taxes & fees

Oct 18 - Oct 19

A courtyard with outdoor seating, a fire pit, and a well-maintained garden.

A hotel room with two beds, a desk, a chair, and a TV.

A Courtyard by Marriott hotel with a modern facade, a covered entrance, and landscaped gardens.

A modern bar area with a bar counter, stools, and a television mounted above.

9. Courtyard by Marriott St Louis Creve Coeur

Creve Coeur

Scott

₩152,155

₩176,861 total

includes taxes & fees

Oct 25 - Oct 26

The Clayton Plaza Hotel sign with a stone wall and plants in front.

A large conference room with rows of tables and chairs, a podium, and a buffet table with plates and napkins.

A living room with a brown leather sofa, a small table, and a chair. There is a window with curtains, a lamp, and a framed picture on the wall.

A hotel room with two beds, a desk, a chair, and a television.

10. Clayton Plaza Hotel & Extended Stay

Clayton

Sivakumar

₩122,810

₩143,365 total

includes taxes & fees

Oct 25 - Oct 26

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

A casino with multiple gaming tables and slot machines.

A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.

A large hotel with a prominent "RIVER CITY" sign.

11. River City Casino & Hotel

St. Louis

Ashley

₩130,205

₩172,362 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

A hotel room with three computer workstations, each with a monitor, keyboard, and a lamp.

12. Hyatt Place St. Louis/Chesterfield

Chesterfield

Shane

₩161,785

₩187,651 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

A gym with treadmills and exercise equipment.

A hotel room with two beds, a TV, a desk, and a sofa.

An outdoor patio with round tables and chairs, umbrellas, and a brick building in the background.

13. SpringHill Suites St. Louis Brentwood

Brentwood

Cheryl

₩154,782

₩182,625 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

14. Wingate by Wyndham St. Louis Airport

St. Ann

Mary

₩129,745

₩154,057 total

includes taxes & fees

Oct 13 - Oct 14

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

A modern kitchen with a sink, dishwasher, and microwave. There is a large mirror above the sink and a countertop with various items. The room has a neutral color scheme and a view of a living area with a couch and a TV.

A gym with treadmills, exercise bikes, and a mirror.

15. Hampton Inn & Suites St. Louis/South I-55

St. Louis

Shannon

₩141,781

₩163,031 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a central round table, two sofas, and a chandelier.

A hotel room with two beds, a patterned wall, and a view of the city through sheer curtains.

A Drury Plaza hotel with a modern design, featuring a curved facade, large windows, and a Drury Plaza sign on the top.

An indoor swimming pool area with clear signage indicating a depth of 3 feet and a no diving warning.

16. Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

Parvaneh Pattie

₩174,231

₩202,087 total

includes taxes & fees

Oct 12 - Oct 13

A hotel lobby with a hot tub, a pool, and outdoor seating.

A lobby with seating areas, a reception desk, and a view of the lobby in the background.

A modern coffee shop interior with wooden furniture, a coffee bar, and a sign for 'KELSO+BROS Coffee Roasters'.

A large conference room with rows of chairs, a patterned carpet, and a ceiling with recessed lighting and a chandelier.

17. Drury Plaza Hotel St. Louis Creve Coeur

Creve Coeur

Eryn

₩175,723

₩204,257 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

18. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

St. Louis

Thomas

₩167,543

₩192,661 total

includes taxes & fees

Oct 25 - Oct 26

A hotel with a covered entrance, a tower with signage, and a landscaped area with planters.

A hotel room with purple walls, a flat-screen TV, a bed, a dining table with chairs, a sofa, and a window with curtains.

A covered outdoor seating area with a pergola, surrounded by landscaped bushes and a paved walkway.

A hotel lobby with multiple seating areas, including round tables and sofas, and a reception desk with a green plant.

19. La Quinta Inn & Suites by Wyndham St. Louis Westport

Westport

Gary

₩106,247

₩124,296 total

includes taxes & fees

Oct 8 - Oct 9

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern lobby with blue seating, a reception desk, and large windows.

20. Hyatt Select St. Louis Airport

Woodson Terrace

Will

₩147,437

₩182,784 total

includes taxes & fees

Oct 15 - Oct 16

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Des Peres attractions

Museum of Transportation

5.0/10 (2 reviews)

The National Museum of Transportation houses over 300 vehicles, including the massive Union Pacific Big Boy steam locomotive. Explore indoor and outdoor exhibits, with miniature train rides available on select days.

See properties

Sugar Creek Park

Sugar Creek Park offers 20 acres of serene recreation with paved trails winding through woods and open fields. Families can enjoy the playground and sports facilities while picnicking in this peaceful Des Peres retreat.

See properties

Learn more about Des Peres

Just minutes from St. Louis, this charming suburb offers family-friendly recreation at Sugar Creek Park with playgrounds and walking trails. Spend an afternoon exploring the fascinating Museum of Transportation where vintage trains and automobiles bring America's transit history to life.

See all hotels in Des Peres

A museum exhibit with vintage vehicles including a 1934 Ford Phalet car and a fire truck.

Top Des Peres Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"We really enjoyed staying here. The breakfast was delicious each morning. The 5:30 Kickback was a pleasant surprise and was also delicious each evening. It was also nice to be so close to the Arch."

Hyatt Regency St. Louis at The Arch

8/10 Good

"The location is fantastic. I had an amazing view of the Arch directly outside my window, the staff was extremely helpful and friendly, and the bar downstairs was also a great spot. Unfortunately, the hotel itself was disappointing. My room was a nice size, but it felt old, dark, and in serious need of an update. Even with the incredible Arch view, the window had a cloudy white film between the panes AND dead bugs along it, which really took away from the view. Also, NO full-length mirror anywhere! In a room this size, I don't understand how that's possible. I literally had to stand on the toilet to see the bottom half of my outfit in the bathroom mirror. The bathroom itself could also use updating. The water pressure was okay, but the shower head was not great. One other heads-up: guest packages are handled by the FedEx location inside the hotel, which charges $4 PER PACKAGE for pickup. Amazon split my order into two packages, so I unexpectedly paid $8. I definitely would've made other arrangements had I known. Overall, you can't beat the location and the staff was wonderful, but the rooms need some serious TLC to match what I'd expect from a Hyatt Regency."

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"Fantastic stay at the Drury Inn St. Louis at Union Station. The location is excellent, especially if you’re in town for an event downtown. The hotel was clean, comfortable, and incredibly convenient, and the staff was friendly and welcoming from check-in to checkout. One of the biggest standouts with Drury is the value. Between the complimentary breakfast, evening food and drinks, and the overall quality of the stay, you really feel like you’re getting more than what you paid for. The room was comfortable, everything was well maintained, and the hotel had a great atmosphere. Being right by Union Station and close to the major downtown attractions made getting around St. Louis incredibly easy. I’ve stayed in plenty of hotels while traveling, and this was easily one of the better experiences. I would absolutely stay here again and would recommend it to anyone visiting St. Louis. Five stars all the way."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"I enjoyed the atmosphere from the moment I arrived. The young man who checked me in was professional but friendly and welcoming—- like I mattered. It’s rare and was felt."

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"Nice place"

Moonrise Hotel

10/10 Excellent

"Great family trip great business trip whatever the occasion is it’s amazing"

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

10/10 Excellent

"Very good location for the arch and other local attactions."

The West End

10/10 Excellent

"The room and hotel was immaculate. Really nice to have secure off street parking in this area of stl. There are lots of small boutique restaurants in the area. The room was TINY! It served the purpose we needed it for."

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Great stay and rooms were very clean,amenities provided was a plus"

More cheap stays in Des Peres

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

₩106,155

₩122,066 total

Oct 13 - Oct 14

includes taxes & fees

8.4/10 Very Good! (1,164 reviews)

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

₩119,903

₩140,202 total

Nov 1 - Nov 2

includes taxes & fees

7.8/10 Good! (1,000 reviews)

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

₩120,617

₩143,218 total

Oct 12 - Oct 13

includes taxes & fees

9.2/10 Wonderful! (3,269 reviews)

The West End

4215 Lindell Blvd St. Louis MO

₩111,151

₩156,775 total

Nov 1 - Nov 2

includes taxes & fees

8.6/10 Excellent! (665 reviews)

Hampton Inn St. Charles St. Peters

3720 W Clay St St. Charles MO

₩159,072

₩182,809 total

Oct 25 - Oct 26

includes taxes & fees

8.2/10 Very Good! (1,006 reviews)

AC Hotel St. Louis Clayton

227 South Central Ave St. Louis MO

₩172,090

₩200,895 total

Oct 25 - Oct 26

includes taxes & fees

Frequently asked questions

What's the best place for a stay in Des Peres?

Clayton Plaza Hotel & Extended Stay, located 6.2 mi (9.9 km) from the heart of Des Peres, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Hyatt Regency St. Louis at The Arch and Pear Tree Inn St. Louis Airport. See all available top hotels, or vacation rentals in Des Peres.

If I need to cancel my hotel reservation in Des Peres, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Des Peres.

Where can I learn more about changing or cancelling my trip to Des Peres?

To find more details about picking new dates or cancelling your trip to Des Peres, head over to our customer service page.

Where is the best place to stay with easy access to Museum of Transportation?

Pear Tree Inn St. Louis Fenton is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located 2.1 mi (3.4 km) from Museum of Transportation. Other good choices within a few miles include Drury Inn & Suites St. Louis Fenton and Courtyard by Marriott St. Louis West County.

What about the best place to stay near Sugar Creek Park?

One of the top choices for your stay is Courtyard by Marriott St. Louis West County, located 1.8 mi (2.9 km) from Sugar Creek Park, and this 3-star hotel offers a restaurant and an indoor pool. Residence Inn by Marriott St. Louis West County and La Quinta Inn & Suites by Wyndham St Louis Route 66 are a couple of other good options within 5 miles.

What's the best place to stay near Lambert-St. Louis International Airport (STL)?

Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.

What is staying in Des Peres like?

Visitors can enjoy all that Des Peres has to offer including the restaurants, shopping, and sporting events. Tourists can also enjoy the city's parks and museums. Top sights around the area include St. Louis Zoo and St. Louis Union Station. In Des Peres, there are 2 hotels and other accommodations to choose from. Find out more about Des Peres.

What is there to see in Des Peres?

A favorite place to visit is Museum of Transportation. Additionally, you'll find St. Louis Zoo and St. Louis Union Station in the area. Check out what more to see and do in Expedia's Des Peres guide.

What's the weather like in Des Peres?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Des Peres is 52 inches.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Des Peres on Expedia.com

Find hotels in Des Peres, MO from ₩122,066

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Des Peres

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Des Peres hotels

1. Best Western St. Louis-Kirkwood Route 66

2. La Quinta Inn & Suites by Wyndham St Louis Route 66

3. Holiday Inn St Louis SW - Route 66 by IHG

4. Best Western Plus Fenton

5. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

6. Comfort Suites St. Louis - Sunset Hills

7. Drury Inn & Suites Southwest St. Louis

8. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

9. Courtyard by Marriott St Louis Creve Coeur

10. Clayton Plaza Hotel & Extended Stay

11. River City Casino & Hotel

12. Hyatt Place St. Louis/Chesterfield

13. SpringHill Suites St. Louis Brentwood

14. Wingate by Wyndham St. Louis Airport

15. Hampton Inn & Suites St. Louis/South I-55

16. Drury Plaza Hotel St. Louis Chesterfield

17. Drury Plaza Hotel St. Louis Creve Coeur

18. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

19. La Quinta Inn & Suites by Wyndham St. Louis Westport

20. Hyatt Select St. Louis Airport

Stay near popular Des Peres attractions

Museum of Transportation

Sugar Creek Park

Learn more about Des Peres

Top Des Peres Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Hyatt Regency St. Louis at The Arch

Drury Plaza Hotel St. Louis Union Station

Pear Tree Inn St. Louis Airport

Clayton Plaza Hotel & Extended Stay

Moonrise Hotel

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

The West End

Hollywood Casino & Hotel St. Louis

More cheap stays in Des Peres

Best Western St. Louis Inn

Tru By Hilton St. Louis Downtown

Pear Tree Inn St. Louis Airport

The West End

Hampton Inn St. Charles St. Peters

AC Hotel St. Louis Clayton

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app