The Best Hotels Closest to Houston Natural Science Museum in Houston for 2026

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Our top choices for Houston Natural Science Museum hotels

A stately building with a symmetrical facade, large windows, and a central entrance.

1. The Marlene Inn

Montrose, 2.8 km from Houston Natural Science Museum

Brenagh

₩500,324 total

includes taxes & fees

Nov 10 - Nov 11

A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

2. La Maison in Midtown an urban B&B

Midtown, 2.9 km from Houston Natural Science Museum

Justin

₩284,311 total

includes taxes & fees

Nov 17 - Nov 18

A modern building with multiple floors, large windows, and outdoor seating area with chairs and tables.

3. Hotel Saint Augustine

Montrose, 1.7 km from Houston Natural Science Museum

Jacqueline

₩434,072 total

includes taxes & fees

Nov 8 - Nov 9

A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.

4. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

1.4 km from Houston Natural Science Museum

Walter

₩349,148 total

includes taxes & fees

Nov 9 - Nov 10

A modern building with a sign reading 'INTERCONTINENTAL' and 'SAFINA MEDITERRANEAN'.

5. InterContinental Houston by IHG

Texas Medical Center, 2.2 km from Houston Natural Science Museum

Luke

₩268,579 total

includes taxes & fees

Nov 22 - Nov 23

A grand staircase with a green garland and golden bows, flanked by wooden paneling and framed artwork on the walls.

6. La Colombe d'Or Hotel

Montrose, 2.2 km from Houston Natural Science Museum

Keeshaun

₩644,657 total

includes taxes & fees

Nov 8 - Nov 9

A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

7. Hyatt Place Houston Medical Center

Texas Medical Center, 3 km from Houston Natural Science Museum

Joel

₩198,715 total

includes taxes & fees

Nov 26 - Nov 27

8. Hyatt House Houston Medical Center

Texas Medical Center, 3 km from Houston Natural Science Museum

Chafae

₩198,715 total

includes taxes & fees

Nov 26 - Nov 27

An outdoor patio area with round wooden tables and wicker chairs, featuring a lantern and modern lighting fixtures.

9. Hilton Garden Inn Houston Medical Center, TX

Texas Medical Center, 2 km from Houston Natural Science Museum

Shatara

₩181,039 total

includes taxes & fees

Dec 3 - Dec 4

A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

10. Downtowner Inns - Houston Downtown

Midtown, 3.1 km from Houston Natural Science Museum

Israel

₩152,480 total

includes taxes & fees

Nov 9 - Nov 10

A spacious living area with a dining table, chairs, and a chandelier.

11. Hotel Zaza Houston Museum District

0.3 km from Houston Natural Science Museum

Suzanne

₩370,774 total

includes taxes & fees

Nov 22 - Nov 23

A rooftop pool area with lounge chairs and a view of a tall building at night.

12. The Westin Houston Medical Center/Museum District

Texas Medical Center, 1.8 km from Houston Natural Science Museum

Leonardo

₩245,704 total

includes taxes & fees

Nov 15 - Nov 16

13. Home2 Suites by Hilton Houston Medical Center, TX

Texas Medical Center, 2 km from Houston Natural Science Museum

Brad

₩202,310 total

includes taxes & fees

Nov 22 - Nov 23

A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

14. Sentral Forme Houston

0.5 km from Houston Natural Science Museum

ebony noelle

₩276,372 total

includes taxes & fees

Nov 30 - Dec 1

A modern lobby with a reception desk, seating area, and a large abstract wall mural.

15. Houston Marriott Medical Center/Museum District

Texas Medical Center, 1.7 km from Houston Natural Science Museum

Vanessa

₩286,761 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a grand chandelier, a reception desk, and a carpet with the hotel's name.

16. Blossom Hotel Houston, Curio Collection by Hilton

Texas Medical Center, 2.7 km from Houston Natural Science Museum

Michael

₩233,905 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with a central island, stainless steel bar stools, a black refrigerator, and white cabinetry.

17. Modern B & B

Montrose, 2.3 km from Houston Natural Science Museum

LISA

₩178,687 total

includes taxes & fees

Nov 8 - Nov 9

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

18. Hilton Houston Plaza/Medical Center

Texas Medical Center, 1.9 km from Houston Natural Science Museum

Cynthia

₩133,882 total

includes taxes & fees

Nov 22 - Nov 23

A modern dining area with a long table and chairs, a chandelier, and a television on the wall.

19. Hampton Inn & Suites Houston Medical Center NRG Park

Texas Medical Center, 3.2 km from Houston Natural Science Museum

Richard

₩174,977 total

includes taxes & fees

Nov 15 - Nov 16

A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

20. DoubleTree by Hilton Houston Medical Center Hotel & Suites

Texas Medical Center, 2.2 km from Houston Natural Science Museum

Danny

₩182,071 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare popular hotels close to Houston Natural Science Museum

Property	Property class	Guest rating
The Marlene Inn	4.0 star property	10.0 Exceptional 40 reviews	View
La Maison in Midtown an urban B&B	3.5 star property	9.8 Exceptional 608 reviews	View
Hotel Saint Augustine	3.5 star property	9.6 Exceptional 190 reviews	View
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only	3.5 star property	9.6 Exceptional 221 reviews	View
InterContinental Houston by IHG	4.0 star property	9.4 Exceptional 1,007 reviews	View

Hotels recommended for families near Houston Natural Science Museum

Hotel Zaza Houston Museum District

South Central Houston

₩370,774 total

includes taxes & fees

Nov 22 - Nov 23

Other attractions near Houston Natural Science Museum

An art gallery with wooden floors and walls, featuring several framed paintings.

Houston Museum of Fine Arts

9.4/10 (258 reviews)

Architecturally stunning and filled with pieces by renowned artists of the world, this museum is a must-see for art lovers.

See properties

Top Houston Natural Science Museum Hotel Reviews

InterContinental Houston by IHG

Texas Medical Center

10/10 Excellent

Noemi

A large indoor swimming pool with multiple lounge areas and a city view.

Hilton Americas-Houston

Downtown Houston

10/10 Excellent

Daisy

Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG

Braeswood Place

10/10 Excellent

Nage

A modern hotel lobby with a fireplace, seating area, and a decorative ceiling.

Homewood Suites by Hilton Houston Memorial

Memorial

10/10 Excellent

Carlos

Hotel Zaza Houston Museum District

South Central Houston

10/10 Excellent

Kasey

A rooftop pool area with a covered seating area, a pool with a metal railing, and a cityscape view in the background.

Holiday Inn Express Houston - Galleria Area by IHG

The Galleria

10/10 Excellent

Great experience from check-in to check-out. The hotel lobby smelled amazing as soon as I walked in. Check-in was quick and easy. Staff were friendly. My room was on the 2nd floor, so easy access to the pool and fitness room. Room was huge and clean and looked exactly like the online pictures. The layout of the room and bathroom was great (with plenty of countertop space). There was a fridge, microwave, and Keurig coffee maker. Instead of an iron/ironing board, there was a steamer in the closet....

Jemille

A hotel lobby with a hot tub, a pool, and a dining area.

Drury Inn & Suites Houston Near the Galleria

The Galleria

10/10 Excellent

Drury Inn was very quaint charming place to stay. Located off the highway, but you might almost miss it if you aren’t careful. The inn had very comfy beds and had microwave and mini refrigerator in the room. Shower was good although water pressure could have been better. Room could have been more spacious but had all the basics. Also it was very nice to have a cocktail/dinner hour each evening…a big bonus if you are just tired and don’t feel like going out. Breakfast also was very good...

Elizabeth

Hilton Garden Inn Houston Medical Center, TX

Texas Medical Center

10/10 Excellent

Tony

The Westin Houston Medical Center/Museum District

Texas Medical Center

10/10 Excellent

Janet

Hyatt Place Houston Medical Center

Texas Medical Center

10/10 Excellent

I recently stayed at this hotel, and I can't say enough good things about the staff. They were incredibly friendly and nice. I asked them to decorate a room last minute for my friend's birthday, and they went above and beyond. My friend walked into a beautifully decorated room and even had cake!! The staff was the sweetest and always had a smile on their faces. Thank you so much for everything you did!

Awura

A modern indoor pool area with a wooden table and chairs, a vase with flowers, and a view of the outside buildings.

Best Western Plus Downtown Inn & Suites

Fourth Ward

10/10 Excellent

David

A spacious lobby with a central staircase, a reception desk, and a large plant.

Embassy Suites by Hilton Houston Downtown Convention Center

Downtown Houston

10/10 Excellent

Jeffrey

A reception area with a modern design, featuring a reception desk with a digital display, purple illuminated panels, and a dark wood finish wall.

Haven Inn & Suites Downtown Houston

Northside

10/10 Excellent

Morgan

A grand staircase with multiple steps, black railings, and lit candles on each step.

Magnolia Hotel Houston, A Tribute Portfolio Hotel

Downtown Houston

10/10 Excellent

Eden

Frequently Asked Questions

What's the area like around Houston Natural Science Museum?

Houston Natural Science Museum is located in an area of Houston known for its top museums and popular art scene. If you're looking for a convenient place to stay, check out the 209 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Houston Natural Science Museum?

Adjacent to Houston Natural Science Museum, Hotel Zaza Houston Museum District is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a restaurant. Other good options within a short distance include Sentral Forme Houston and Americas Best Value Inn Medical Center Downtown.

How many hotels should I expect to find near Houston Natural Science Museum?

Expedia has 209 hotels and other accommodations within a mile from Houston Natural Science Museum.

If I need to cancel the hotel reservation for my stay near Houston Natural Science Museum, will I receive a refund?

Yes! Most hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to view the top deals on offer near Houston Natural Science Museum.

Where can I learn more about changing or cancelling my trip in the area near Houston Natural Science Museum?

To find more details about rescheduling or cancelling your stay near Houston Natural Science Museum, head over to our customer service page.

What can I see and do near Houston Natural Science Museum?

You might want to spend some time browsing the exhibits at Houston Museum of Fine Arts, Menil Collection, or Health Museum. Sights like Reliant Park, Eldorado Ballroom, and Freedmenstown are must-sees while exploring the area. You can catch a show at Main Street Theater - Rice Village, House of Blues Houston, and Jesse H. Jones Hall.

How can I get to Houston Natural Science Museum?

With so many choices for transportation, exploring the area around Houston Natural Science Museum is easy. You can walk to nearby metro stations including Palm Center Transit Center, MacGregor Park/Martin Luther King Jr. Station, and UH South/University Oaks Station. To venture out into the surrounding area, hop aboard a train at Kinder Station or M. D. Anderson Station.

Find hotels near Houston Natural Science Museum, Houston from ₩130,325

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Treat yourself

Be picky

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Property class

Guest rating

Our top choices for Houston Natural Science Museum hotels

1. The Marlene Inn

2. La Maison in Midtown an urban B&B

3. Hotel Saint Augustine

4. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

5. InterContinental Houston by IHG

6. La Colombe d'Or Hotel

7. Hyatt Place Houston Medical Center

8. Hyatt House Houston Medical Center

9. Hilton Garden Inn Houston Medical Center, TX

10. Downtowner Inns - Houston Downtown

11. Hotel Zaza Houston Museum District

12. The Westin Houston Medical Center/Museum District

13. Home2 Suites by Hilton Houston Medical Center, TX

14. Sentral Forme Houston

15. Houston Marriott Medical Center/Museum District

16. Blossom Hotel Houston, Curio Collection by Hilton

17. Modern B & B

18. Hilton Houston Plaza/Medical Center

19. Hampton Inn & Suites Houston Medical Center NRG Park

20. DoubleTree by Hilton Houston Medical Center Hotel & Suites

Compare popular hotels close to Houston Natural Science Museum

Hotels recommended for families near Houston Natural Science Museum

Hotel Zaza Houston Museum District

Other attractions near Houston Natural Science Museum

Houston Museum of Fine Arts

Top Houston Natural Science Museum Hotel Reviews

InterContinental Houston by IHG

10/10 Excellent

Frequently Asked Questions

What's the area like around Houston Natural Science Museum?

What's the best hotel to stay near Houston Natural Science Museum?

How many hotels should I expect to find near Houston Natural Science Museum?

If I need to cancel the hotel reservation for my stay near Houston Natural Science Museum, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Houston Natural Science Museum?

What can I see and do near Houston Natural Science Museum?

How can I get to Houston Natural Science Museum?