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Our top choices for Illinois Medical District hotels

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (453 reviews)
"Easy check in/out process and good breakfast:)"
United States
Belle
The price is ₩166,322
₩195,244 total
includes taxes & fees
Jan 27 - Jan 28
Hampton Inn & Suites Chicago Medical District UIC

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,348 reviews)
"Really great hotel and super up to date!"
United States
Alanna
The price is ₩147,978
₩173,712 total
includes taxes & fees
Jan 29 - Jan 30
Hyatt House Chicago Medical/University District

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,459 reviews)
"Enjoyed our stay very much"
United States
Jiya
The price is ₩128,931
₩151,352 total
includes taxes & fees
Feb 1 - Feb 2
Hyatt Place Chicago Medical/University District

Claridge House Chicago, Tapestry Collection by Hilton

Claridge House Chicago, Tapestry Collection by Hilton
4.0 star property
Gold Coast, 5.5 km from Illinois Medical District
9.0 out of 10, Wonderful, (1,514 reviews)
"Clean room, staff was very nice and it was in a very nice location! "
United States
Mary
The price is ₩82,897
₩140,313 total
includes taxes & fees
Feb 9 - Feb 10
Claridge House Chicago, Tapestry Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,336 reviews)
"Great stay"
United States
Blake
The price is ₩154,425
₩231,166 total
includes taxes & fees
Feb 3 - Feb 4
Sable at Navy Pier Chicago, Curio Collection by Hilton

Moxy Chicago Downtown

Moxy Chicago Downtown
3.0 star property
River North, 4.3 km from Illinois Medical District
9.4 out of 10, Exceptional, (874 reviews)
"Great hotel, lots of fun and great location! "
United States
Amber
The price is ₩158,234
₩185,752 total
includes taxes & fees
Feb 8 - Feb 9
Moxy Chicago Downtown

Thompson Chicago, by Hyatt

Thompson Chicago, by Hyatt
4.5 star property
Gold Coast, 5.3 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,315 reviews)
"Love this hotel, right in the middle of a great area re: restaurants, bars, night scene, etc. "
United States
Yoshio
The price is ₩212,444
₩292,608 total
includes taxes & fees
Feb 12 - Feb 13
Thompson Chicago, by Hyatt

citizenM Chicago Downtown

citizenM Chicago Downtown
4.0 star property
Theatre District, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (4,197 reviews)
"Very nice Hotel, great atmosphere friendly staff. I had a great stay!"
United States
Lucie Saint Jean
The price is ₩150,908
₩177,152 total
includes taxes & fees
Jan 28 - Jan 29
citizenM Chicago Downtown

Hilton Garden Inn Chicago Downtown/Magnificent Mile

Hilton Garden Inn Chicago Downtown/Magnificent Mile
3.0 star property
River North, 4.7 km from Illinois Medical District
8.6 out of 10, Excellent, (4,350 reviews)
"All things about this hotel was good from the location to the staff"
United States
Cisco
The price is ₩124,946
₩146,675 total
includes taxes & fees
Feb 4 - Feb 5
Hilton Garden Inn Chicago Downtown/Magnificent Mile

Level Chicago Fulton Market

Level Chicago Fulton Market
4.0 star property
West Loop, 3.2 km from Illinois Medical District
9.2 out of 10, Wonderful, (390 reviews)
"The experience of the hotel was amazing"
United States
Lachelle
Level Chicago Fulton Market

The Hoxton Chicago

The Hoxton Chicago
4.0 star property
2.7 km from Illinois Medical District
9.0 out of 10, Wonderful, (1,000 reviews)
"Amazing, I loved my stay"
United States
Valerie
The Hoxton Chicago

Hampton Inn Chicago West Loop Fulton Market Area

Hampton Inn Chicago West Loop Fulton Market Area
2.5 star property
3.1 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,000 reviews)
"Nice hotel and staff. "
United States
Wendy
The price is ₩185,559
₩217,828 total
includes taxes & fees
Jan 30 - Jan 31
Hampton Inn Chicago West Loop Fulton Market Area

The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast
4.0 star property
Gold Coast, 5.6 km from Illinois Medical District
8.2 out of 10, Very Good, (1,274 reviews)
"Solid stay in a great part of town"
United States
Michael
The price is ₩168,343
₩197,616 total
includes taxes & fees
Jan 25 - Jan 26
The Chicago Hotel Collection Ambassador Gold Coast

ACME Hotel Chicago, Outset Collection by Hilton

ACME Hotel Chicago, Outset Collection by Hilton
3.5 star property
River North, 4.7 km from Illinois Medical District
9.0 out of 10, Wonderful, (1,940 reviews)
"Love the location, room, staff, and bar."
United States
Jason
The price is ₩106,925
₩125,519 total
includes taxes & fees
Feb 1 - Feb 2
ACME Hotel Chicago, Outset Collection by Hilton

Springhill Suites by Marriott Chicago Downtown/ River North

Springhill Suites by Marriott Chicago Downtown/ River North
3.5 star property
River North, 4.4 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,026 reviews)
"Room was super clean, staff was friendly and helpful, and the area was a perfect spot in town!"
United States
Zachary
The price is ₩168,490
₩197,789 total
includes taxes & fees
Feb 1 - Feb 2
Springhill Suites by Marriott Chicago Downtown/ River North

Hyatt House Chicago West Loop

Hyatt House Chicago West Loop
3.5 star property
2.3 km from Illinois Medical District
8.8 out of 10, Excellent, (1,170 reviews)
"Staff is wonderful, nice clean rooms, centrally located, loved staying here. "
United States
Cassandra
The price is ₩210,979
₩247,668 total
includes taxes & fees
Jan 30 - Jan 31
Hyatt House Chicago West Loop

LondonHouse Chicago, Curio Collection by Hilton

LondonHouse Chicago, Curio Collection by Hilton
4.5 star property
The Loop, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,569 reviews)
"Clean accommodations and friendly staff."
United States
usha
The price is ₩203,038
₩238,346 total
includes taxes & fees
Feb 22 - Feb 23
LondonHouse Chicago, Curio Collection by Hilton

Radisson Blu Aqua Hotel Chicago

Radisson Blu Aqua Hotel Chicago
4.5 star property
4.9 km from Illinois Medical District
8.6 out of 10, Excellent, (1,841 reviews)
"Excellent front desk, rooms, pool/whirlpool and especially gym. "
United States
Victoria Lynn Davis
The price is ₩225,630
₩302,960 total
includes taxes & fees
Feb 8 - Feb 9
Radisson Blu Aqua Hotel Chicago

The Whitehall Hotel, BW Premier Collection

The Whitehall Hotel, BW Premier Collection
3.5 star property
Streeterville, 5.3 km from Illinois Medical District
8.2 out of 10, Very Good, (3,899 reviews)
"Location, breakfast was good, room was nice. "
United States
Traci
The price is ₩112,153
₩131,657 total
includes taxes & fees
Jan 26 - Jan 27
The Whitehall Hotel, BW Premier Collection

Embassy Suites by Hilton Chicago Downtown River North

Embassy Suites by Hilton Chicago Downtown River North
4.0 star property
River North, 4.7 km from Illinois Medical District
8.6 out of 10, Excellent, (5,592 reviews)
"Always a great stay, clean, great breakfast, great pool. "
United States
Zachary
The price is ₩154,981
₩181,931 total
includes taxes & fees
Feb 5 - Feb 6
Embassy Suites by Hilton Chicago Downtown River North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

O'Hare

Home to O'Hare International Airport, this transportation hub offers easy access to downtown via the Blue Line. The area also hosts various corporate headquarters and international consulates.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 10 hotels and other accommodations in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.
Where can I learn more about changing or cancelling my trip to Illinois Medical District?
To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.
What can I see and do in this Chicago neighborhood?
Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Michael Jordan Statue and National Museum of Mexican Art are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.