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Our top choices for Illinois Medical District hotels

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (508 reviews)
"Room was clean, staff was SUPER friendly and made the experience great."
United States
Megan
The price is ₩194,520
₩228,348 total
includes taxes & fees
Mar 15 - Mar 16
Hampton Inn & Suites Chicago Medical District UIC

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,437 reviews)
"Great rooms, hot breakfast and great service! "
United States
Ana
The price is ₩187,383
₩219,970 total
includes taxes & fees
Mar 22 - Mar 23
Hyatt House Chicago Medical/University District

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,488 reviews)
"Enjoyed our stay very much"
United States
Jiya
The price is ₩193,285
₩226,898 total
includes taxes & fees
Mar 22 - Mar 23
Hyatt Place Chicago Medical/University District

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,403 reviews)
"Great stay"
United States
Blake
The price is ₩207,523
₩293,850 total
includes taxes & fees
Mar 24 - Mar 25
Sable at Navy Pier Chicago, Curio Collection by Hilton

Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites
3.5 star property
Streeterville, 5.6 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,902 reviews)
"The staff and the cleanliness of the Hotel was amazing and the views where great!!"
United States
Oliver
The price is ₩153,231
₩179,879 total
includes taxes & fees
Mar 17 - Mar 18
Hilton Chicago/Magnificent Mile Suites

The Wade

The Wade
4.5 star property
Streeterville, 5.6 km from Illinois Medical District
8.4 out of 10, Very Good, (1,719 reviews)
"Thoroughly enjoyed my stay at The Wade"
United States
Danielle
The price is ₩160,825
₩188,794 total
includes taxes & fees
Mar 22 - Mar 23
The Wade

Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,498 reviews)
"Amazing place, breakfast is great , location is great - honestly great hotel! "
United States
Brisa
The price is ₩203,088
₩279,984 total
includes taxes & fees
Mar 18 - Mar 19
Hotel Riu Plaza Chicago

Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park
4.5 star property
The Loop, 4.8 km from Illinois Medical District
8.6 out of 10, Excellent, (2,076 reviews)
"Great place "
United States
Kamilah
The price is ₩249,575
₩344,941 total
includes taxes & fees
Mar 24 - Mar 25
Fairmont Chicago at Millennium Park

Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,229 reviews)
"Place is always top notch..stay here anytime we stay in Chicago."
United States
Jon
The price is ₩180,442
₩264,054 total
includes taxes & fees
Mar 29 - Mar 30
Swissotel - Chicago

L7 Chicago by LOTTE

L7 Chicago by LOTTE
4.5 star property
Theatre District, 4.5 km from Illinois Medical District
9.6 out of 10, Exceptional, (3,749 reviews)
"Great location and overall great hotel."
United States
Fernando
The price is ₩203,081
₩238,398 total
includes taxes & fees
Mar 31 - Apr 1
L7 Chicago by LOTTE

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very Good, (9,938 reviews)
"Great location, beautiful historic hotel with clean, updated rooms. "
United States
Jennifer
The price is ₩143,531
₩168,494 total
includes taxes & fees
Apr 1 - Apr 2
Congress Plaza Hotel

Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop
3.0 star property
The Loop, 4.1 km from Illinois Medical District
8.8 out of 10, Excellent, (1,894 reviews)
"Absolutely enjoyed my time here"
United States
Quayshaun
The price is ₩181,258
₩212,779 total
includes taxes & fees
Mar 18 - Mar 19
Hilton Garden Inn Chicago Downtown South Loop

Eurostars Magnificent Mile

Eurostars Magnificent Mile
4.0 star property
River North, 4.8 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,314 reviews)
"Great stay "
United States
Kylee
The price is ₩212,466
₩249,415 total
includes taxes & fees
Mar 23 - Mar 24
Eurostars Magnificent Mile

Pendry Chicago

Pendry Chicago
4.5 star property
Theatre District, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (1,141 reviews)
"Excellent hotel and location."
United States
Marcelo
The price is ₩295,092
₩407,035 total
includes taxes & fees
Mar 23 - Mar 24
Pendry Chicago

Palmer House a Hilton Hotel

Palmer House a Hilton Hotel
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,329 reviews)
"Excellent stay, we loved it "
United States
Melani
The price is ₩198,420
₩269,812 total
includes taxes & fees
Apr 5 - Apr 6
Palmer House a Hilton Hotel

Arlo Chicago

Arlo Chicago
4.0 star property
Theatre District, 4.5 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,019 reviews)
"Clean hotel, helpful staff, restaurant food was delicious, great atmosphere, fabulous location!"
United States
Jennifer
The price is ₩211,138
₩291,904 total
includes taxes & fees
Mar 29 - Mar 30
Arlo Chicago

Freehand Chicago

Freehand Chicago
4.0 star property
River North, 4.7 km from Illinois Medical District
8.0 out of 10, Very Good, (2,798 reviews)
"I enjoyed my stay"
United States
Emily
The price is ₩115,529
₩161,602 total
includes taxes & fees
Mar 24 - Mar 25
Freehand Chicago

Hyatt Centric The Loop Chicago

Hyatt Centric The Loop Chicago
4.0 star property
Theatre District, 3.9 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,410 reviews)
"Super comfy beds, helpful staff, free coffee and snacks and an amazing location "
United States
Stephanie
The price is ₩206,963
₩242,953 total
includes taxes & fees
Mar 20 - Mar 21
Hyatt Centric The Loop Chicago

FOUND Hotel Chicago River North

FOUND Hotel Chicago River North
2.0 star property
River North, 4.3 km from Illinois Medical District
8.4 out of 10, Very Good, (486 reviews)
"Amazing staff and very clean, modern rooms!"
United States
genevieve
The price is ₩124,890
₩146,609 total
includes taxes & fees
Mar 22 - Mar 23
FOUND Hotel Chicago River North

Omni Chicago Hotel

Omni Chicago Hotel
4.5 star property
Streeterville, 5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,711 reviews)
"Great place to stay "
United States
Juliet
The price is ₩222,809
₩304,876 total
includes taxes & fees
Mar 18 - Mar 19
Omni Chicago Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

Lincoln Park

Upscale national retailers, boutiques, and bookstores abound in this affluent area, alongside numerous restaurants and coffee shops. Must-see attractions include Lincoln Park Zoo, Chicago History Museum, and North Avenue Beach. Easily accessible via CTA transit and major roads.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
Expedia has 9 Illinois Medical District hotels and other accommodations, and one might make a good home base for venturing out into the greater Chicago area.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.
Where can I learn more about changing or cancelling my trip to Illinois Medical District?
To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.
What can I see and do in this Chicago neighborhood?
Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.