Find hotels in Illinois Medical District, Chicago from ₩108,620

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Nov 27 - Nov 28
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Discover 4,806 Illinois Medical District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Exterior
Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District

3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1222)
"Good place to stay "
United States
Matthew
The price is ₩161,032
₩189,036 total
includes taxes & fees
Dec 7 - Dec 8
Hyatt House Chicago Medical/University District
Business center
Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC

2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (349)
"Clean nice place to stay "
United States
Daryl
The price is ₩127,526
₩149,703 total
includes taxes & fees
Dec 7 - Dec 8
Hampton Inn & Suites Chicago Medical District UIC
Lobby
Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District

3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1409)
"Great location, comfortable "
United States
Tracy
The price is ₩154,142
₩180,949 total
includes taxes & fees
Dec 7 - Dec 8
Hyatt Place Chicago Medical/University District
Terrace/patio
DoubleTree by Hilton Chicago - Magnificent Mile

DoubleTree by Hilton Chicago - Magnificent Mile

4.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.8 out of 10, Excellent, (2165)
"Great stay "
United States
Melinda
The price is ₩142,706
₩167,522 total
includes taxes & fees
Dec 7 - Dec 8
DoubleTree by Hilton Chicago - Magnificent Mile
Reception
Eurostars Magnificent Mile

Eurostars Magnificent Mile

4.0 star property
River North, 4.8 km from Illinois Medical District
8.8 out of 10, Excellent, (3135)
"Location was great "
United States
Hamik
The price is ₩150,079
₩176,178 total
includes taxes & fees
Dec 29 - Dec 30
Eurostars Magnificent Mile
Reception
River Hotel

River Hotel

4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (4850)
"Front desk is amazing, rooms are clean and great location"
United States
Glen
The price is ₩133,902
₩157,187 total
includes taxes & fees
Dec 7 - Dec 8
River Hotel
Cocktail bar
Aloft Chicago Mag Mile

Aloft Chicago Mag Mile

3.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2942)
"Great location!!"
United States
sarah e
The price is ₩131,621
₩154,508 total
includes taxes & fees
Dec 7 - Dec 8
Aloft Chicago Mag Mile
Terrace/patio
Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton

4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2250)
"Room was spotless…staff was great!"
United States
Tamika
The price is ₩128,062
₩200,339 total
includes taxes & fees
Dec 23 - Dec 24
Sable at Navy Pier Chicago, Curio Collection by Hilton
Ballroom
Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites

3.5 star property
Streeterville, 5.6 km from Illinois Medical District
9.0 out of 10, Wonderful, (3397)
"Great stay!"
United States
Rose
The price is ₩121,822
₩142,998 total
includes taxes & fees
Dec 7 - Dec 8
Hilton Chicago/Magnificent Mile Suites
Bar (on property)
Hilton Garden Inn Chicago Downtown/Magnificent Mile

Hilton Garden Inn Chicago Downtown/Magnificent Mile

3.0 star property
River North, 4.7 km from Illinois Medical District
8.4 out of 10, Very Good, (4207)
"Great location. "
United States
Rodger
The price is ₩117,488
₩137,919 total
includes taxes & fees
Dec 9 - Dec 10
Hilton Garden Inn Chicago Downtown/Magnificent Mile
Exterior
Hilton Chicago

Hilton Chicago

4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.4 out of 10, Very Good, (2322)
"Clean Rooms & very nice staff"
United States
Teresa
The price is ₩154,698
₩224,524 total
includes taxes & fees
Dec 22 - Dec 23
Hilton Chicago
Lobby
citizenM Chicago Downtown

citizenM Chicago Downtown

4.0 star property
Theatre District, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (4090)
"Clean rooms, friendly staff, great breakfast, amazing location. "
Canada
Gokce
The price is ₩157,140
₩184,467 total
includes taxes & fees
Dec 24 - Dec 25
citizenM Chicago Downtown
Exterior
FOUND Hotel Chicago River North

FOUND Hotel Chicago River North

2.0 star property
River North, 4.3 km from Illinois Medical District
8.4 out of 10, Very Good, (343)
"love this place definitely coming back !"
United States
Dayanara
The price is ₩92,529
₩108,620 total
includes taxes & fees
Dec 7 - Dec 8
FOUND Hotel Chicago River North
Front of property
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (2881)
"Great service, great breakfast and a nice room "
United States
DeAnna
The price is ₩133,368
₩197,944 total
includes taxes & fees
Dec 8 - Dec 9
Hotel Riu Plaza Chicago
Cocktail bar
Freehand Chicago

Freehand Chicago

4.0 star property
River North, 4.7 km from Illinois Medical District
8.0 out of 10, Very Good, (2611)
"Rooms are clean, staff are nice and friendly "
United States
Karen
The price is ₩117,142
₩163,264 total
includes taxes & fees
Dec 8 - Dec 9
Freehand Chicago
Exterior
Crowne Plaza Chicago West Loop by IHG

Crowne Plaza Chicago West Loop by IHG

3.5 star property
2.7 km from Illinois Medical District
9.0 out of 10, Wonderful, (1717)
"The location was great!!"
United States
Yvette
The price is ₩186,806
₩219,291 total
includes taxes & fees
Nov 30 - Dec 1
Crowne Plaza Chicago West Loop by IHG
Banquet hall
Congress Plaza Hotel

Congress Plaza Hotel

3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very Good, (9664)
"Great stay comfortable bed and great location!"
United States
Kimberly Noel
The price is ₩162,905
₩191,236 total
includes taxes & fees
Dec 23 - Dec 24
Congress Plaza Hotel
Lobby
Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown

4.0 star property
Theatre District, 4.3 km from Illinois Medical District
9.2 out of 10, Wonderful, (2093)
"Lovely hotel in a great spot!"
United States
Natasha
The price is ₩104,109
₩167,037 total
includes taxes & fees
Dec 21 - Dec 22
Silversmith Hotel Chicago Downtown
Seasonal outdoor pool, open 8:00 AM to 10:00 PM, sun loungers
Holiday Inn & Suites Chicago - Downtown by IHG

Holiday Inn & Suites Chicago - Downtown by IHG

3.0 star property
West Loop, 3 km from Illinois Medical District
8.4 out of 10, Very Good, (1013)
"Really great location and warm and friendly staff"
United Kingdom
David
The price is ₩133,375
₩174,117 total
includes taxes & fees
Dec 7 - Dec 8
Holiday Inn & Suites Chicago - Downtown by IHG
Pool
Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop

3.0 star property
The Loop, 4.1 km from Illinois Medical District
8.8 out of 10, Excellent, (1732)
"Clean room, great hot tub."
United States
SHARON
The price is ₩115,826
₩135,964 total
includes taxes & fees
Dec 21 - Dec 22
Hilton Garden Inn Chicago Downtown South Loop
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.
Downtown Chicago showing a city

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile - River North

Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

The Loop - Downtown which includes a river or creek

The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

River North showing railway items, street scenes and a city

River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

Chicago which includes modern architecture and a city

Lincoln Park

Upscale national retailers, boutiques, and bookstores abound in this affluent area, alongside numerous restaurants and coffee shops. Must-see attractions include Lincoln Park Zoo, Chicago History Museum, and North Avenue Beach. Easily accessible via CTA transit and major roads.

Top Illinois Medical District Hotel Reviews

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton

10/10 Excellent
"had a great time. Goo"
Omid 2-night trip
Posted 3 hours ago
Sable at Navy Pier Chicago, Curio Collection by Hilton

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
If you're searching for places to stay in Chicago, choose from one of Expedia's 10 hotels and other accommodations in Illinois Medical District.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.
Where can I learn more about changing or cancelling my trip to Illinois Medical District?
To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.
What can I see and do in this Chicago neighborhood?
Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Michael Jordan Statue and National Museum of Mexican Art are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.