Find hotels in José Domingo Espinar, San Miguelito from ₩42,566

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 6 - Dec 7
Tomorrow
Dec 7 - Dec 8
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Filter by

Guest rating
Guest rating
Star rating

Discover 1,696 José Domingo Espinar hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Apartment, 3 Bedrooms, Accessible, Pool View | Children's area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City

2.0 star property
José Domingo Espinar
The price is ₩104,958
₩115,454 total
includes taxes & fees
Dec 8 - Dec 9
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
10.1 km from José Domingo Espinar
8.4 out of 10, Very Good, (2293)
"The room was clean and the staff were nice! "
United States
CECILIA
The price is ₩162,031
₩178,234 total
includes taxes & fees
Dec 23 - Dec 24
Crowne Plaza Panama Airport by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
12.4 km from José Domingo Espinar
9.0 out of 10, Wonderful, (1002)
"Great staff, perfect location, and delicious breakfast. "
United States
Tatiana
The price is ₩297,591
₩327,350 total
includes taxes & fees
Dec 12 - Dec 13
Central Hotel Panama Casco Viejo
Living area
ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport

2.0 star property
9.7 km from José Domingo Espinar
9.0 out of 10, Wonderful, (32)
"Very nice boutique hotel"
United States
Fernando
The price is ₩176,761
₩229,436 total
includes taxes & fees
Dec 7 - Dec 8
ORHO HOTEL BOUTIQUE PANAMA Airport
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

4.0 star property
12.5 km from José Domingo Espinar
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is ₩327,787
₩360,566 total
includes taxes & fees
Dec 10 - Dec 11
La Concordia Boutique Hotel
Reception
Hotel Coral Suites

Hotel Coral Suites

3.5 star property
8.8 km from José Domingo Espinar
9.0 out of 10, Wonderful, (1002)
"Great place for the price. "
United States
Ryan
The price is ₩98,102
₩107,912 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Coral Suites
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
9.5 km from José Domingo Espinar
9.0 out of 10, Wonderful, (1000)
"I loved everything about my stay "
United States
Stephanie
The price is ₩264,523
₩290,975 total
includes taxes & fees
Dec 16 - Dec 17
Waldorf Astoria Panama
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5.0 star property
19.9 km from José Domingo Espinar
8.0 out of 10, Very Good, (1002)
"Clean rooms , friendly staff , had great experience "
United States
Saro
The price is ₩257,968
₩283,765 total
includes taxes & fees
Dec 16 - Dec 17
The Westin Playa Bonita Panama
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 star property
8.6 km from José Domingo Espinar
8.6 out of 10, Excellent, (1857)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is ₩184,200
₩202,620 total
includes taxes & fees
Dec 24 - Dec 25
Riande Aeropuerto Hotel & Casino
Aerial view
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

3.5 star property
24.9 km from José Domingo Espinar
7.8 out of 10, Good, (661)
"Beautiful place to stay for one night. A little over priced for Panama but the service and the food were excellent. "
Canada
Dan
The price is ₩184,273
₩202,700 total
includes taxes & fees
Dec 7 - Dec 8
Gamboa Rainforest Reserve
Front of property - evening/night
Principe Hotel and Suites

Principe Hotel and Suites

3.0 star property
8.5 km from José Domingo Espinar
9.0 out of 10, Wonderful, (1581)
"Great hotel, location, food. Highly recommend the sushi restaurant next door.. One of the best ever. "
United States
Lakshmin
The price is ₩73,650
₩81,015 total
includes taxes & fees
Dec 20 - Dec 21
Principe Hotel and Suites
Exterior
Aloft Panama

Aloft Panama

3.5 star property
7.1 km from José Domingo Espinar
8.8 out of 10, Excellent, (889)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is ₩172,342
₩189,577 total
includes taxes & fees
Dec 15 - Dec 16
Aloft Panama
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 star property
9 km from José Domingo Espinar
9.2 out of 10, Wonderful, (1005)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is ₩131,466
₩144,620 total
includes taxes & fees
Dec 8 - Dec 9
TRYP by Wyndham Panamá Centro
Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 star property
8.8 km from José Domingo Espinar
7.6 out of 10, Good, (689)
"The breakfast was great, I love the pool."
United States
Estefani
The price is ₩81,663
₩89,829 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hospedium Princess Hotel Panama
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
3.8 km from José Domingo Espinar
9.6 out of 10, Exceptional, (635)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ₩341,370
₩375,507 total
includes taxes & fees
Dec 12 - Dec 13
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Front of property
Novotel Panama City

Novotel Panama City

4.0 star property
8.2 km from José Domingo Espinar
9.2 out of 10, Wonderful, (1010)
"Room very clean, nice staffs and good location "
United States
Hayden
The price is ₩144,502
₩158,952 total
includes taxes & fees
Dec 9 - Dec 10
Novotel Panama City
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
9.2 km from José Domingo Espinar
9.4 out of 10, Exceptional, (1000)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is ₩270,793
₩297,872 total
includes taxes & fees
Dec 12 - Dec 13
Bristol Panama, a Registry Collection Hotel
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
12.4 km from José Domingo Espinar
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is ₩474,530
₩521,983 total
includes taxes & fees
Dec 24 - Dec 25
Hotel La Compañía Casco Antiguo
Outdoor pool
Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina

3.0 star property
8.7 km from José Domingo Espinar
7.4 out of 10, Good, (267)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is ₩125,206
₩137,727 total
includes taxes & fees
Dec 16 - Dec 17
Ramada Panama Centro Via Argentina
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 star property
9.1 km from José Domingo Espinar
8.4 out of 10, Very Good, (1252)
"Its a very beautiful hotel with view and very good breakfast "
United States
Patrick
The price is ₩193,077
₩212,385 total
includes taxes & fees
Dec 8 - Dec 9
Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in José Domingo Espinar

Find the best José Domingo Espinar areas and neighborhoods for the activities you enjoy most.

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider a stop by Metromall Panama while you're exploring the neighborhood.

Victoriano Lorenzo

Though Victoriano Lorenzo might not have many top sights, you can venture to the surrounding area to see attractions like Panama Viejo and Estadio Rommel Fernandez.

San Antonio

The gardens and shopping are just a few features travelers like about San Antonio. If you want to do some sightseeing nearby, Metromall Panama and Los Pueblos Commercial Center are a few top places to visit.

Rufina Alfaro

If you're looking for some top things to see and do in Rufina Alfaro and surrounding area, you can visit Metromall Panama and Los Pueblos Commercial Center.

Belisario Porras

While there might not be top attractions in Belisario Porras, you can explore the larger area and discover places like Estadio Rommel Fernandez and Metromall Panama.

Top José Domingo Espinar Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Very good breakfast and very nice hotel and close to lots of restaurants "
Michele 4-night trip
Posted 9 hours ago
Hotel Riu Plaza Panama

Explore a world of travel with Expedia

Frequently asked questions

What's it like in José Domingo Espinar?
You'll be sure to have fun visiting San Miguelito's José Domingo Espinar neighborhood.
If I need to cancel my hotel reservation in José Domingo Espinar, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the top deals on offer in José Domingo Espinar.
Where can I learn more about changing or cancelling my trip to José Domingo Espinar?
For more details about changing or cancelling your trip to José Domingo Espinar, go to https://www.expedia.com/service/.
What is there to do around this San Miguelito neighborhood?
A few places to visit in the area around José Domingo Espinar include Estadio Rommel Fernandez, Plaza de Francia, and Metromall Panama. When you're sightseeing in San Miguelito, Los Pueblos Commercial Center and Monte Oscuro are also worth a stop.