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Our top choices for Medical Center District hotels

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,002 reviews)
"Great hotel and amenities, clean, nice bar area and attentive staff. "
United States
Alana
The price is ₩159,991
₩190,116 total
includes taxes & fees
Jan 16 - Jan 17
San Antonio Marriott Northwest Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very Good, (3,171 reviews)
"Great breakfast and very clean"
United States
angelia
The price is ₩129,569
₩153,148 total
includes taxes & fees
Jan 12 - Jan 13
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 star property
Medical Center District
9.0 out of 10, Wonderful, (1,001 reviews)
"The staff were helpful I enjoyed my stay "
United States
Cyril
The price is ₩134,238
₩156,723 total
includes taxes & fees
Jan 18 - Jan 19
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"Clean rooms @ friendly staff!"
United States
LaTishe
The price is ₩129,861
₩153,507 total
includes taxes & fees
Jan 18 - Jan 19
Courtyard by Marriott Medical Center San Antonio

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (230 reviews)
"Good stay and safe area"
United States
Mario
The price is ₩75,159
₩87,749 total
includes taxes & fees
Jan 12 - Jan 13
Studio 6 San Antonio, Tx - Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,285 reviews)
"Great place to stay and visit "
United States
Harry
The price is ₩131,305
₩155,205 total
includes taxes & fees
Jan 18 - Jan 19
Drury Inn & Suites San Antonio Northwest Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,001 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is ₩85,358
₩99,655 total
includes taxes & fees
Jan 12 - Jan 13
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (228 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is ₩92,712
₩116,992 total
includes taxes & fees
Jan 16 - Jan 17
OYO Inn & Suites Medical Center San Antonio

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.6 out of 10, (806 reviews)
"It was good"
United States
Laura
The price is ₩74,400
₩90,873 total
includes taxes & fees
Jan 12 - Jan 13
Studio 6 San Antonio, TX - Medical Center

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,005 reviews)
"This place is great! The location couldnt be bett"
United States
Ryder
The price is ₩91,778
₩107,151 total
includes taxes & fees
Jan 25 - Jan 26
Park Inn by Radisson

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.4 out of 10, Good, (276 reviews)
"Room was good standings, staff was friendly "
United States
Luis
Atria Inn & Suites

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (1,000 reviews)
"Great experience "
United States
John
The price is ₩67,922
₩80,291 total
includes taxes & fees
Jan 12 - Jan 13
Motel 6 San Antonio, TX - Northwest Medical Center

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (499 reviews)
"There was a roach egg casing in the bed. The floors were disgusting and no staff available when checking out. "
United States
Miranda
The price is ₩60,407
₩71,406 total
includes taxes & fees
Jan 12 - Jan 13
Flex Studios

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,367 reviews)
"Great amenities and friendly staff. "
United States
Erica
The price is ₩104,180
₩183,413 total
includes taxes & fees
Jan 26 - Jan 27
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
3.0 star property
Downtown San Antonio, 13 km from Medical Center District
7.8 out of 10, Good, (3,811 reviews)
"Great staff, very clean, and great breakfast buffet"
United States
DEBRA
The price is ₩103,743
₩148,741 total
includes taxes & fees
Feb 8 - Feb 9
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk
2.5 star property
12.9 km from Medical Center District
7.0 out of 10, Good, (1,803 reviews)
"Clean room and staff was very nice and helpful "
United States
Christa
The price is ₩59,080
₩69,837 total
includes taxes & fees
Feb 1 - Feb 2
Red Roof Inn PLUS+ San Antonio Downtown - Riverwalk

Crockett Hotel

Crockett Hotel
3.0 star property
Downtown San Antonio, 12.7 km from Medical Center District
8.8 out of 10, Excellent, (2,536 reviews)
"Friendly staff, great location, good prices. "
United States
Gregorio
The price is ₩130,226
₩153,938 total
includes taxes & fees
Jan 20 - Jan 21
Crockett Hotel

Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk
2.0 star property
Downtown San Antonio, 12.4 km from Medical Center District
9.0 out of 10, Wonderful, (1,833 reviews)
"Wonderful stay"
United States
Marilyn
The price is ₩140,644
₩164,202 total
includes taxes & fees
Jan 13 - Jan 14
Hotel Gibbs Downtown Riverwalk

Drury Inn & Suites San Antonio Riverwalk

Drury Inn & Suites San Antonio Riverwalk
3.0 star property
Downtown San Antonio, 12.2 km from Medical Center District
9.4 out of 10, Exceptional, (1,787 reviews)
"Great location and breakfast."
United States
Amy
The price is ₩175,079
₩206,961 total
includes taxes & fees
Jan 18 - Jan 19
Drury Inn & Suites San Antonio Riverwalk

Days Inn by Wyndham San Antonio Airport

Days Inn by Wyndham San Antonio Airport
2.0 star property
Uptown, 10.2 km from Medical Center District
8.0 out of 10, Very Good, (1,007 reviews)
"great location and value"
United States
Daniel
The price is ₩76,238
₩88,991 total
includes taxes & fees
Jan 12 - Jan 13
Days Inn by Wyndham San Antonio Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio River and Marion Koogler McNay Art Museum.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista while you're in town.

Near East Side

If you're spending some time in Near East Side, Alamodome and Carver Community Cultural Center are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travelers are sure to enjoy a stay in San Antonio's Medical Center District neighborhood. Are you looking for Medical Center District travel tips? Be sure to check out USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighborhood.
What's a favorite place to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include SpringHill Suites by Marriott San Antonio Medical Center/NW and Fairfield Inn & Suites by Marriott San Antonio Medical Center.
How many hotels will I be able to find in Medical Center District?
Expedia has 122 hotels and other accommodations in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Medical Center District.
Where can I learn more about changing or cancelling my trip to Medical Center District?
For more information about changing or cancelling your trip to Medical Center District, go to https://www.expedia.com/service/.
What can I see and do in this San Antonio neighborhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16, and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.