Medical Center District, TX

San Antonio

Photo by Linda Cronan

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Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ₩128,279 per night from Jan 6 to Jan 7
₩128,279
₩151,637 total
Jan 6 - Jan 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,152 reviews)
Yes staff was nice

Reviewed on Jan 4, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ₩158,399 per night from Jan 16 to Jan 17
₩158,399
₩188,223 total
Jan 16 - Jan 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,016 reviews)
It was a great stay nothing to complain about. Liked the service, cleanliness.

Reviewed on Dec 29, 2025

San Antonio Marriott Northwest Medical Center
Hotel Valencia Riverwalk

Hotel Valencia Riverwalk

4.5 out of 5
150 E Houston St San Antonio TX
The price is ₩154,049 per night from Jan 18 to Jan 19
₩154,049
₩223,372 total
Jan 18 - Jan 19
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,321 reviews)
Valet was top notch, check in was smooth and gave us complimentary drinks since we were early. The atmosphere and attentiveness of the staff was phenomenal. Room was spacious and clean and when we had a request- it was answered with eagerness and silliness to help solve our problem ( we needed a ...

Reviewed on Jan 2, 2026

Hotel Valencia Riverwalk
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

3.5 out of 5
9700 West Military Drive San Antonio TX
Fully refundable
The price is ₩108,633 per night from Feb 4 to Feb 5
₩108,633
₩188,076 total
Feb 4 - Feb 5
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,339 reviews)
Balcony had a great view

Reviewed on Jan 3, 2026

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk

3 out of 5
303 Blum Street San Antonio TX
The price is ₩109,211 per night from Jan 14 to Jan 15
₩109,211
₩154,393 total
Jan 14 - Jan 15
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (3,814 reviews)
Excellent! Great location and great customer service!

Reviewed on Jan 3, 2026

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is ₩193,720 per night from Feb 1 to Feb 2
₩193,720
₩228,994 total
Feb 1 - Feb 2
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,287 reviews)
We really loved this property. The room and location were great. Everything was in walking distance, and the staff guided us with directions. We will definitely stay there again when visiting San Antonio.

Reviewed on Jan 3, 2026

Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Medical Center District

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Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Convocation Center.

Northwest Side
It's Texas, of course everything is bigger! #guinessworldrecord #visittexas #hdr #fisheye

Shearer Hills - Ridgeview

If you're spending some time in Shearer Hills - Ridgeview, North Star Mall and San Pedro Driving Range & Par 3 Course are top sights worth seeing.

Shearer Hills - Ridgeview
Brackenridge Park

Midtown

Unique features of Midtown include the river views and bars. Make a stop by San Antonio River or The DoSeum while you're exploring the area.

Midtown
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La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

La Cantera District
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Tobin Hill

Though Tobin Hill might not have many top sights, you can venture to the surrounding area to see attractions like San Antonio River and San Antonio Museum of Art.

Tobin Hill
Marion Koogler McNay Art Museum featuring art and interior views

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio River and Marion Koogler McNay Art Museum.

Uptown


Medical Center District, TX

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