Medical Center District, TX

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions


Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ₩118,419 per night from Nov 17 to Nov 18
₩118,419
₩141,321 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,784 reviews)
"Restaurants and service stations near by. Safe walking areas."

Reviewed on Nov 13, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ₩124,505 per night from Dec 13 to Dec 14
₩124,505
₩149,360 total
Dec 13 - Dec 14
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,203 reviews)
"I made a reservation for 5 rooms. Upon arrival at the hotel, a $50 deposit per room was required, which was supposed to be refunded at the end of our stay. A week later, I received the refund, but $10 per room was deducted for no reason. We only stayed for one night, basically just to sleep, and ..."

Reviewed on Nov 13, 2026

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is ₩120,006 per night from Nov 22 to Nov 23
₩120,006
₩143,216 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is ₩118,819 per night from Nov 27 to Nov 28
₩118,819
₩141,798 total
Nov 27 - Nov 28
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Courtyard by Marriott Medical Center San Antonio
Hotel Valencia Riverwalk, Valencia Collection

Hotel Valencia Riverwalk, Valencia Collection

4.5 out of 5
150 E Houston St San Antonio TX
The price is ₩150,404 per night from Nov 26 to Nov 27
₩150,404
₩217,657 total
Nov 26 - Nov 27
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
Hotel Valencia Riverwalk, Valencia Collection
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is ₩170,681 per night from Nov 22 to Nov 23
₩170,681
₩203,691 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (5,504 reviews)
"They offer a huge free breakfast bar and free snacks and alcoholic/ non alcoholic drinks in the afternoon. Staff was great and location was phenomenal on the Riverwalk!"

Reviewed on Nov 13, 2026

Drury Plaza Hotel San Antonio Riverwalk
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio

The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by Alamo or Alamodome while you're exploring the area.

Uptown Central

While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Shops at Hardy Oak and Alta Vista at Stone Oak while you're in town.



Medical Center District, TX

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