Medical Center District, TX

San Antonio

A cityscape with a prominent tower, a large body of water, and a sunset.
A canal with colorful umbrellas and trees along the banks.
A riverside café with colorful umbrellas and tables.
A tranquil waterway flanked by lush greenery and stone pathways.
A canal with a boat, surrounded by lush greenery and a stone bridge.

Stay near popular Medical Center District attractions


Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

3 out of 5
4431 Horizon Hill Blvd San Antonio TX
The price is ₩133,608 per night from Jul 12 to Jul 13
₩133,608
₩157,922 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (3,478 reviews)
"Clean rooms, excellent service, nice hot tub and pool, and front desk concierge was very helpful."

Reviewed on Jul 9, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

3.5 out of 5
3233 NW Loop 410 San Antonio TX
The price is ₩164,979 per night from Aug 2 to Aug 3
₩164,979
₩196,043 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,113 reviews)
"I rated the experience a 4 overall, but it's really closer to a 3.5. Upon arrival, there was some trash around the front entrance, but it was very windy that day. However, after staying all weekend, it appeared to be an ongoing issue. Once inside, the lobby and all other areas appeared to be consistently ..."

Reviewed on Jul 8, 2026

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

3 out of 5
9806 Interstate Hwy 10 W San Antonio TX
The price is ₩135,399 per night from Jul 26 to Jul 27
₩135,399
₩160,053 total
Jul 26 - Jul 27
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,382 reviews)
"Friendly informative staff. Clean room. Would stay here again."

Reviewed on Jul 6, 2026

Drury Inn & Suites San Antonio Northwest Medical Center
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

3 out of 5
8585 Marriott Dr San Antonio TX
The price is ₩133,909 per night from Aug 1 to Aug 2
₩133,909
₩158,293 total
Aug 1 - Aug 2
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,012 reviews)
"Our stay was good, restaurant, staff, room everything was good service"

Reviewed on Jul 8, 2026

Courtyard by Marriott Medical Center San Antonio
Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk

4 out of 5
105 S Saint Marys Street San Antonio TX
The price is ₩192,574 per night from Aug 7 to Aug 8
₩192,574
₩227,639 total
Aug 7 - Aug 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (4,881 reviews)
"Great location but there were some things we didn't like. The "free" breakfast was so crowded. Also many of the items were not protected as they should be from contamination. The floors were sticky throughout the hotel. I think next time we might opt for a more elevated experience."

Reviewed on Jul 8, 2026

Drury Plaza Hotel San Antonio Riverwalk
Riverwalk Plaza

Riverwalk Plaza

4 out of 5
100 Villita Street San Antonio TX
The price is ₩128,695 per night from Jul 12 to Jul 13
₩128,695
₩152,129 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
8/10 Very Good! (6,482 reviews)
"The building is older, as is normal for the area. The pool is in a courtyard and is nice enough, but it feels like everyone is watching you as the rooms have windows looking down on it. The room was average. The bed was comfortable. The only thing that gave us an issue was the TV remote. Frank, the ..."

Reviewed on Jul 9, 2026

Riverwalk Plaza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio

The stunning river views and popular shops are just a few highlights of Downtown San Antonio. Make a stop by San Antonio River or Alamo while you're exploring the area.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Uptown

While visiting Uptown, you might make a stop by sights like San Antonio Zoo and Aquarium and San Antonio River.

La Cantera District

If you're spending some time in La Cantera District, Six Flags Fiesta Texas and The Shops of La Cantera are top sights worth seeing.

Stone Oak

Travelers come to Stone Oak for its abundant dining options, and you can see top attractions like Stone Ridge Market and Shops at Hardy Oak while you're in town.



Medical Center District, TX

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