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Check prices for these dates

Tonight
Oct 10 - Oct 11
Tomorrow
Oct 11 - Oct 12
Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

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Our top choices for Mesopotamia hotels

1. To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
Germany
Andreas Johann
₩85,910
₩98,317 total
includes taxes & fees
Nov 1 - Nov 2
To Spiti tis Sofias

2. Limneon Resort & Spa

Limneon Resort & Spa
Kastoria
Canada
Konstantinos
₩126,398
₩166,120 total
includes taxes & fees
Oct 12 - Oct 13
Limneon Resort & Spa

3. Chloe Hotel

Chloe Hotel
Kastoria
United States
Tammy
₩106,015
₩127,928 total
includes taxes & fees
Oct 12 - Oct 13
Chloe Hotel

4. Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
Kastoria
United States
Michal
₩172,042
₩199,882 total
includes taxes & fees
Nov 8 - Nov 9
Esperos Palace Luxury & Spa Hotel

5. Calma Hotel & Spa

Calma Hotel & Spa
Kastoria
New Zealand
Robert
₩106,179
₩125,086 total
includes taxes & fees
Nov 3 - Nov 4
Calma Hotel & Spa

6. Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
United Kingdom
Clare
₩116,325
₩135,106 total
includes taxes & fees
Oct 15 - Oct 16
Kyknos De Luxe Hotel

7. Hotel Anastassiou

Hotel Anastassiou
Kastoria
United States
Jeffrey
₩66,623
₩76,411 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Anastassiou

8. Orologopoulos Mansion

Orologopoulos Mansion
Kastoria
United States
Iren
₩161,036
₩188,885 total
includes taxes & fees
Nov 8 - Nov 9
Orologopoulos Mansion

9. Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
United States
Carmen
₩101,123
₩115,592 total
includes taxes & fees
Nov 10 - Nov 11
Guesthouse Vissinokipos

10. Andromeda Boutique hotel

Andromeda Boutique hotel
Kastoria
₩102,313
₩135,709 total
includes taxes & fees
Nov 10 - Nov 11
Andromeda Boutique hotel

11. Anesis Hotel

Anesis Hotel
Kastoria
Canada
Adam
₩72,703
₩85,567 total
includes taxes & fees
Oct 15 - Oct 16
Anesis Hotel

12. Le Marron

Le Marron
Voio
₩189,138
₩219,298 total
includes taxes & fees
Nov 10 - Nov 11
Le Marron

13. Lūma Retreat

Lūma Retreat
Kastoria
₩107,348
₩124,919 total
includes taxes & fees
Oct 12 - Oct 13
Lūma Retreat

14. Guest House Ilektra

Guest House Ilektra
Voio
United Kingdom
Maria
₩66,264
₩78,262 total
includes taxes & fees
Oct 11 - Oct 12
Guest House Ilektra

15. Guesthouse Monopati

Guesthouse Monopati
Amyntaio
₩96,016
₩112,050 total
includes taxes & fees
Oct 12 - Oct 13
Guesthouse Monopati

16. Arhontiko Christodoulou

Arhontiko Christodoulou
Prespes
₩74,950
₩85,868 total
includes taxes & fees
Nov 10 - Nov 11
Arhontiko Christodoulou
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Top Mesopotamia Hotel Reviews

Orologopoulos Mansion

Orologopoulos Mansion

10/10 Excellent
"It is amazing!"
Iren 2-night trip
Posted 1 day ago
Orologopoulos Mansion
Guesthouse Vissinokipos

Guesthouse Vissinokipos

10/10 Excellent
"The location of the hotel provided a fabulous view of Kastoria, the lake and the surrounding mountains from thebalcony. You just have to be very careful navigating the winding road, especially at night. The staff were very welcoming friendly and accommodating with my needs. The room was also clean, and spacious. The breakfast included in the room price was a k so extensive and a very nice way to start the day. Overall, it was an enjoyable experience. I will definitely stay there again when visiting family in Kastoria."
Nicolas 1-night trip
Posted 2 days ago
Guesthouse Vissinokipos
Kyknos De Luxe Hotel

Kyknos De Luxe Hotel

10/10 Excellent
"We had a lovely stay in kastoria, the hotel was great and breakfast was amazing. As a family of 4 the space in the room was ideal and the owners were extremely welcoming."
Clare 1-night trip
Posted 2 months ago
Kyknos De Luxe Hotel
Limneon Resort & Spa

Limneon Resort & Spa

10/10 Excellent
"We loved our stay very much and will definitely be returning from the staff to the location and simply beautiful views we couldn’t ask for anything better the only suggestion is that they add dresser’s with draws so you can putt your cloths out instead of having to use your suit cases."
George 16-night trip
Posted 2 months ago
Limneon Resort & Spa
Calma Hotel & Spa

Calma Hotel & Spa

10/10 Excellent
"If you’re looking for a hotel, that is clean, spacious, warm and inviting this is the place for you. It has the perfect location to be out of the way but close enough to all of Kastoria and surrounding villages. Staff were kind and exceptional. Everyone was extremely helpful, courteous and made us feel like we were home. Rooms are spacious, constantly clean and replenished with towels daily. We had a simple corner suite that didn’t overlook much in a view but it was quiet all day long which was refreshing. Pool was beautifully maintained as well as the entire property. Pool did get very busy with locals due to the extreme heat, but with a morning reservation at the pool you had no problem having a spot even if you came back late in the afternoon. Breakfast was delicious with its standard staples but with new items as well. We cannot be more happy with our stay and we hope that you will consider booking this location as we know you will not be disappointed."
Patricia 10-night trip
Posted 2 months ago
Calma Hotel & Spa
Guest House Ilektra

Guest House Ilektra

10/10 Excellent
"Friendly and courteous hosts, great food and excellent service "
Pantelia 1-night trip
Posted 10 months ago
Guest House Ilektra

More cheap stays in Mesopotamia

Hotel Anastassiou

Hotel Anastassiou

1st km Highway Kastoria-Athens Kastoria Western Macedonia
₩66,623
₩76,411 total
Nov 8 - Nov 9
includes taxes & fees
Hotel Anastassiou
Anesis Hotel

Anesis Hotel

Grammou 10 Kastoria
₩72,703
₩85,567 total
Oct 15 - Oct 16
includes taxes & fees
9/10 Wonderful! (9 reviews)
Anesis Hotel
Arhontiko Christodoulou

Arhontiko Christodoulou

vrontero Prespes
₩74,950
₩85,868 total
Nov 10 - Nov 11
includes taxes & fees
Arhontiko Christodoulou

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Hotel Anastassiou. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best vacation home rentals that Mesopotamia has to offer?
Anastasia s Kastoria Cozy Modern Garden Retreat: This vacation home rental outside of Mesopotamia offers a garden, a barbecue grill, and free WiFi to help you feel perfectly comfortable in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
Where can I learn more about changing or cancelling my trip to Mesopotamia?
For more details about picking new dates or cancelling your trip to Mesopotamia, click here.
What is the best accommodation for staying close to Macedonia Airport (SKG)?
Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.
What is staying in Mesopotamia like?
Travelers to Mesopotamia will find plenty to explore and enjoy. There are 49 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Folklore Museum of Kastoria, Neolithic Lakeside Settlement, and Kastoria Lake. You'll also find Petrified Forest Museum and Kastoria Aquarium in the area. Check out what more to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.