A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

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Check availability on Mytilene Luxury Hotels

Tonight
Aug 27 - Aug 28
Tomorrow
Aug 28 - Aug 29
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Mytilene luxury hotels

Free daily continental breakfast
Front of property - evening/night
Front of property - evening/night
Property entrance

1. Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
  • Luxuriate in this Lesvos boutique haven where pillowtop beds meet spa indulgences, all within steps of the beach and local art.
₩223,261
₩260,708 total
includes taxes & fees
Sep 20 - Sep 21
Theofilos Paradise Boutique Hotel
Seasonal outdoor pool
2 restaurants; lunch and dinner served
Exclusive Room | Minibar, in-room safe, desk, soundproofing
2 restaurants; lunch and dinner served

2. Heliotrope Hotels

Heliotrope Hotels
Lesvos
₩202,894
₩238,402 total
includes taxes & fees
Aug 30 - Aug 31
Heliotrope Hotels
Exterior
Reception
Reception
Deluxe Suite | Terrace/patio

3. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
  • Seaside luxury awaits at this Greek retreat, where beachfront bliss meets wellness indulgence with 3 indoor pools and a full-service spa.
₩193,838
₩236,551 total
includes taxes & fees
Sep 2 - Sep 3
Mythical Coast Wellness Retreat
Garden
Outdoor dining
Property grounds
Mansion Standard Suite with Sea View | Balcony view

4. Loriet Hotel

Loriet Hotel
Lesvos
₩195,379
₩230,169 total
includes taxes & fees
Sep 22 - Sep 23
Loriet Hotel
Terrace/patio
2 bars/lounges
Terrace/patio
Deluxe Double Room, Sea View | Premium bedding, Select Comfort beds, minibar, in-room safe

5. Elysion Hotel

Elysion Hotel
Lesvos
  • Experience tranquil luxury and refined comfort at this 5-star seaside retreat with outdoor tennis courts and multiple dining options.
₩219,126
₩304,604 total
includes taxes & fees
Sep 26 - Sep 27
Elysion Hotel
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Top Mytilene Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Mytilene vacation?
Mytilene has some interesting things to see and do including Port of Mytilene and Mytilini Castle, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Mytilene?
Mythical Coast Wellness Retreat is a luxury hotel with 5 restaurants and 5 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Elysion Hotel and Theofilos Paradise Boutique Hotel are two other upscale options for your trip.
When can I expect good weather in Mytilene?
Planning for the weather is a good way to make your trip to Mytilene relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 77°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Mytilene is 34 inches.
What's there to see and do in Mytilene?
Take in the sights and attractions that Mytilene offers with a visit to Port of Mytilene, Mytilini Castle, and Olive-press Museum of Archipelagos Society. If you have a little extra time during your trip, you might want to make a stop at Roman Aqueduct at Moria and Thermes Gera Hot Springs.