A coastal town with terracotta-roofed houses, a beach, and a castle on a hill.

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Check availability on Mytilene Resorts & Hotels with Spas

Tonight
Oct 11 - Oct 12
Tomorrow
Oct 12 - Oct 13
Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

Our top choices for Mytilene hotels with a spa

A modern bathroom with a glass-enclosed shower, a bench, and a bed with towels.
A multi-story hotel with a central courtyard, balconies, and a rooftop terrace.
A buffet with various food items including fruits, vegetables, and desserts.
A rooftop pool area with a glass balustrade, a lounge chair, and a sun umbrella.

1. Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel
Lesvos
  • Escape to a boutique spa retreat with hot springs and massage therapy in the heart of Mytilene.
₩164,686
₩195,417 total
includes taxes & fees
Oct 11 - Oct 12
Theofilos Paradise Boutique Hotel
A person standing on a balcony overlooking a pool and a modern building with a clear view of the sea.
A person standing by a glass railing, holding a cup, with a view of the sea and mountains in the background.
A modern building with a balcony overlooking a landscaped area with palm trees and a view of the sea.
A modern hotel with a swimming pool, outdoor seating, and a view of the sea.

2. Elysion Hotel

Elysion Hotel
Lesvos
  • Immerse in a rejuvenating Greek island escape with tennis courts, seasonal pools, and serene balconied rooms overlooking Lesvos.
₩146,522
₩166,512 total
includes taxes & fees
Nov 1 - Nov 2
Elysion Hotel
A woman sitting by a pool with a drink, overlooking a modern outdoor bar and lounge area with outdoor seating.
A modern, well-lit living room with a sofa, a dining area with a table and chairs, and a kitchen with a sink and cabinets.
A residential area with a swimming pool, outdoor seating, and a view of the sea.
A modern house with a stone facade, a covered patio, and a swimming pool.

3. Elies Residences

Elies Residences
Lesvos
  • Relax in premium villas with spa treatments and outdoor pool in this serene getaway.
₩148,002
₩165,132 total
includes taxes & fees
Oct 11 - Oct 12
Elies Residences
Two wicker chairs with cushions, a decorative plant, and a small round table with candles and a tray.
A modern hotel room with a large bed, a dining area with a view of the sea, and a balcony with a table and chairs.
A dining area with a table and chairs, a vase with a flower, and a view of the sea through large windows.
A resort with a pool, outdoor seating, and a view of the sea at dusk.

4. Mythical Coast Wellness Retreat

Mythical Coast Wellness Retreat
Lesvos
  • Relax in a coastal spa haven with hydrotherapy, hot springs, and three indoor pools for ultimate rejuvenation.
₩117,953
₩151,787 total
includes taxes & fees
Oct 31 - Nov 1
Mythical Coast Wellness Retreat
A balcony with a view of the sea, a seating area, and a bed with pillows.
A modern outdoor seating area with a view of the sea, featuring a sofa, a wooden table, and a potted plant.
A person standing by a hot tub on a balcony overlooking the sea.
A balcony with a view of the sea, a white pitcher with plants, and a building with a red roof.

5. Olive Green Studios and Apartments

Olive Green Studios and Apartments
Lesvos
  • Rejuvenating seaside retreat offers in-room massages and a tranquil garden sanctuary, perfect for a wellness escape by the beach.
₩120,004
₩134,460 total
includes taxes & fees
Oct 13 - Oct 14
Olive Green Studios and Apartments
View all properties

Choose what matters most at spa hotels in Mytilene

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Mytilene Hotel Reviews

Theofilos Paradise Boutique Hotel

Theofilos Paradise Boutique Hotel

8/10 Good
"Staff was nice. Large breakfast spread. Location is great."
Caroline 1-night trip
Posted 2 months ago
Theofilos Paradise Boutique Hotel

Frequently asked questions

Looking to vacation at a spa hotel in Mytilene?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the museums and churches in Mytilene—your cultural tour starts here. Enjoy the architecture and sea views during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Mytilene?
Mythical Coast Wellness Retreat is a top beach spa hotel featuring 5 restaurants, 5 bars, 3 indoor pools, and 5 cafes. Treat yourself to a facial, body scrub, or Swedish massage at Mythical Coast Spa. Another popular spa hotel in Mytilene is Theofilos Paradise Boutique Hotel.
How many spa hotels are there in Mytilene?
Among Expedia's 88 accommodation options in Mytilene, there are 2 spa hotels.
What's there to see and do in Mytilene?
When you're in Mytilene, enjoy exploring the sights and attractions here including Port of Mytilene, Mytilini Castle, and Roman Aqueduct at Moria. If you have a bit of extra time while you're in the area, you might want to check out Thermes Gera Hot Springs and St Hermogenes Charamida Lesvos.
What is a Mytilene spa hotel?
Spa hotels in Mytilene feature full on-site spas offering services like facials and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.