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Our top choices for San Francisco hotels

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,011 reviews)
"The staff was very friendly and the whole property made you feel Safe!"
United States
Michael
The price is ₩399,709
₩439,680 total
includes taxes & fees
Feb 22 - Feb 23
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,000 reviews)
"Super friendly staff"
United States
Geoffrey
The price is ₩192,118
₩211,329 total
includes taxes & fees
Feb 13 - Feb 14
Sheraton Grand Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,157 reviews)
"Great staff, breakfast and location "
Canada
Corinne
The price is ₩158,308
₩174,139 total
includes taxes & fees
Feb 26 - Feb 27
Ramada Plaza by Wyndham Panama Punta Pacifica

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
"Overall stay was great..staff was super friendly"
United States
Bjorna
The price is ₩175,356
₩192,892 total
includes taxes & fees
Feb 21 - Feb 22
Courtyard by Marriott Panama Multiplaza Mall

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (937 reviews)
"Perfect stay for a few days at Panama!"
United States
Maria
The price is ₩170,199
₩187,219 total
includes taxes & fees
Feb 13 - Feb 14
Aloft Panama

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (564 reviews)
"Great location, friendly staff, clean rooms, very comfortable beds. "
United States
Sharna
The price is ₩230,155
₩253,170 total
includes taxes & fees
Feb 17 - Feb 18
Residence Inn by Marriott Panama City

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,012 reviews)
"Clean wonderful room, great staff, big breakfast"
Canada
John
The price is ₩203,689
₩224,064 total
includes taxes & fees
Feb 27 - Feb 28
Las Americas Golden Tower Panama

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,398 reviews)
"Clean room,helpful staff around the hotel,good food options"
United States
Umar
Megapolis Hotel Panamá

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,174 reviews)
"Breakfast buffet was great. "
United States
Carol
The price is ₩156,656
₩172,322 total
includes taxes & fees
Feb 3 - Feb 4
Plaza Paitilla Inn Hotel

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (165 reviews)
"Clean room good place to stay "
United States
Gideon
The price is ₩84,029
₩293,289 total
includes taxes & fees
Feb 2 - Feb 3
Boutique Apartments Panamá Coco del Mar

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,525 reviews)
"Nice comfortable hotel and very friendly staff."
Canada
norah
Decapolis Hotel Panama City

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (29 reviews)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Wanders & Yoo

Wanders & Yoo
4.0 star property
San Francisco
8.0 out of 10, Very Good, (11 reviews)
"Cool and modern condos, great location and views."
United States
Jorge
Wanders & Yoo

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is ₩221,889
₩463,130 total
includes taxes & fees
Feb 1 - Feb 2
Wanders Panama by Boutique Apartments

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
7.0 out of 10, Good, (6 reviews)
"For me was very convenient "
United States
Natalia
The price is ₩84,025
₩92,428 total
includes taxes & fees
Feb 18 - Feb 19
Casa Orquídea

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
2.8 out of 10, (3 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is ₩255,298
₩280,828 total
includes taxes & fees
Feb 1 - Feb 2
Dovle Residences by HMS-Preferred Member

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is ₩60,602
₩277,305 total
includes taxes & fees
Feb 2 - Feb 3
Living 73 Panamá by Boutique Apartments

Dovle 506 in Ciudad de Panam

Dovle 506 in Ciudad de Panam
2.0 star property
San Francisco
The price is ₩233,209
₩305,699 total
includes taxes & fees
Feb 9 - Feb 10
Dovle 506 in Ciudad de Panam

Relaxing 2BR Apt at Coco del mar

Relaxing 2BR Apt at Coco del mar
2.0 star property
San Francisco
The price is ₩295,291
₩324,820 total
includes taxes & fees
Feb 18 - Feb 19
Relaxing 2BR Apt at Coco del mar

Smart Loft-style 1BR Apt Near to Shops

Smart Loft-style 1BR Apt Near to Shops
2.0 star property
San Francisco
The price is ₩198,228
₩267,220 total
includes taxes & fees
Feb 4 - Feb 5
Smart Loft-style 1BR Apt Near to Shops
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or Palacio de las Garzas while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and Palacio de las Garzas are top sights worth seeing.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Plaza Paitilla Inn Hotel is the highest ranked property in San Francisco. This hotel is a short 2-minute walk from Avenida Balboa, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Residence Inn by Marriott Panama City and JW Marriott Panama.
How many hotels will I find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 253 San Francisco hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.
What is there to do in this Panama City neighborhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.