Find hotels in San Francisco, Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Francisco hotels

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,003 reviews)
"Very enjoyable stay"
Canada
Lynnette
The price is ₩355,324
₩390,856 total
includes taxes & fees
Apr 5 - Apr 6
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,009 reviews)
"Nice convenient placed hotel. Pleasant and very helpful staff. Lovely comfortable place to stay"
United Kingdom
Mark
The price is ₩189,761
₩208,737 total
includes taxes & fees
Apr 3 - Apr 4
Sheraton Grand Panama

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,123 reviews)
"excellent value for the money with a very good breakfast buffet"
Canada
Gary
The price is ₩161,743
₩177,925 total
includes taxes & fees
Mar 20 - Mar 21
Plaza Paitilla Inn Hotel

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (987 reviews)
"Very clean room great staff "
United States
Derenique Shann
The price is ₩168,110
₩184,921 total
includes taxes & fees
Mar 21 - Mar 22
Aloft Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,150 reviews)
"Always my hotel in Panama. Good location great staff "
United States
Nizar
The price is ₩143,283
₩157,607 total
includes taxes & fees
Mar 27 - Mar 28
Ramada Plaza by Wyndham Panama Punta Pacifica

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,599 reviews)
"Clean room and the staff was very nice"
United States
Robert
The price is ₩199,153
₩219,068 total
includes taxes & fees
Mar 16 - Mar 17
Decapolis Hotel Panama City

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,453 reviews)
"clean room, friendly staff, reasonably priced"
United States
Gregory
The price is ₩253,387
₩278,726 total
includes taxes & fees
Apr 6 - Apr 7
Megapolis Hotel Panamá

Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,004 reviews)
"Hotel is in a great location for partying ans shopping "
United States
Brendia
The price is ₩157,922
₩173,714 total
includes taxes & fees
Apr 11 - Apr 12
Courtyard by Marriott Panama Multiplaza Mall

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is ₩94,394
₩327,231 total
includes taxes & fees
Apr 1 - Apr 2
Living 73 Panamá by Boutique Apartments

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,000 reviews)
"Excelente Hotel!"
Mexico
Juan Carlos
The price is ₩242,696
₩266,969 total
includes taxes & fees
Apr 10 - Apr 11
Las Americas Golden Tower Panama

Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
7.0 out of 10, Good, (10 reviews)
"Clean room, stairs to get from the top of elevator to the room, bathroom was outside the room."
Canada
Larry
The price is ₩126,083
₩138,691 total
includes taxes & fees
Mar 18 - Mar 19
Casa Orquídea

Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is ₩254,713
₩509,276 total
includes taxes & fees
Apr 7 - Apr 8
Wanders Panama by Boutique Apartments

Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (578 reviews)
"Large room, nice location, nice to have laundry available "
United States
Janet
The price is ₩266,175
₩292,793 total
includes taxes & fees
Apr 5 - Apr 6
Residence Inn by Marriott Panama City

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
2.5 star property
San Francisco
4.6 out of 10, (4 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is ₩245,723
₩270,295 total
includes taxes & fees
Mar 16 - Mar 17
Dovle Residences by HMS-Preferred Member

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (173 reviews)
"The best place "
United States
Julio
The price is ₩74,166
₩291,646 total
includes taxes & fees
Apr 1 - Apr 2
Boutique Apartments Panamá Coco del Mar

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.8 out of 10, Good, (33 reviews)
"The place was clean nice an its comfortable an the view is to kill for amazing ‼️"
United States
Odaine
The price is ₩41,749
₩209,839 total
includes taxes & fees
Mar 16 - Mar 17
Boutique Apartments Atlapa

w Engaging 1BR w Balcony in San Francisco

w Engaging 1BR w Balcony in San Francisco
2.0 star property
San Francisco
The price is ₩167,242
₩231,350 total
includes taxes & fees
Mar 22 - Mar 23
w Engaging 1BR w Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is ₩162,368
₩225,989 total
includes taxes & fees
Mar 22 - Mar 23
w Bright 1BR w Private Balcony in San Francisco

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
15.7 km from San Francisco
8.6 out of 10, Excellent, (2,477 reviews)
"Great bed, quiet even though you are near the airport"
United States
howard matt
The price is ₩202,272
₩222,499 total
includes taxes & fees
Apr 14 - Apr 15
Crowne Plaza Panama Airport by IHG

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
15.1 km from San Francisco
9.0 out of 10, Wonderful, (80 reviews)
"Clean room, friendly staff."
United States
Richard
The price is ₩179,797
₩233,376 total
includes taxes & fees
Mar 16 - Mar 17
ORHO HOTEL BOUTIQUE PANAMA Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels will I find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 250 San Francisco hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.
What is there to do in this Panama City neighborhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.