San Luis Obispo Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ₩234,741 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Where to stay in San Luis Obispo
Find the best San Luis Obispo areas and neighborhoods for the activities you enjoy most. Learn more about San Luis Obispo
Downtown San Luis Obispo
4 out of top 10 points of interest in this area
4.5/5(102 area reviews)
If you're spending some time in Downtown San Luis Obispo, Downtown SLO Farmers' Market and Mission San Luis Obispo de Tolosa are top sights worth seeing.
Find the Best San Luis Obispo Vacation Packages
San Luis Obispo Hotel Deals
Madonna Inn
100 Madonna Road San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is ₩268,197 per night from Mar 18 to Mar 19
₩268,197
₩355,420 total
Mar 18 - Mar 19
includes taxes & fees
9.2/10 Wonderful! (1,387 reviews)
Poolside is
Reviewed on Mar 17, 2026
Quality Suites Downtown San Luis Obispo
1631 Monterey St San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is ₩200,099 per night from Mar 26 to Mar 27
₩200,099
₩264,807 total
Mar 26 - Mar 27
includes taxes & fees
9.4/10 Exceptional! (1,375 reviews)
Staff was very friendly and helpful at check-in, the grounds are well taken care of and set up so well with little nooks everywhere to sit outside, fire pits were nice too. Great breakfast! Would stay again!
Reviewed on Mar 17, 2026
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
1845 Monterey St. San Luis Obispo CA
Fully refundableReserve now, pay when you stay
The price is ₩209,644 per night from Mar 22 to Mar 23
₩209,644
₩238,354 total
Mar 22 - Mar 23
includes taxes & fees
9/10 Wonderful! (1,904 reviews)
Yes
Reviewed on Mar 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in San Luis Obispo
California Polytechnic State University, San Luis Obispo
Explore the campus of California Polytechnic State University, San Luis Obispo during your visit to San Luis Obispo. Stroll along the area's beautiful beaches, or simply savor its top-notch restaurants.
Bubblegum Alley
Colorful pieces of chewed gum, some of which have been turned into art pieces, decorate the walls of this narrow lane.
French Hospital Medical Center
Though French Hospital Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of San Luis Obispo while you are here.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
