Find hotels in Sanibel Isles, Sanibel

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sanibel Isles hotels

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
23.4 km from Sanibel Isles
7.4 out of 10, Good, (198 reviews)
"The room was new, high quality and staff was excellent!"
United States
Brian
The price is ₩129,855
₩144,788 total
includes taxes & fees
Feb 15 - Feb 16
Woodspring Suites Fort Myers - Cape Coral

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
23 km from Sanibel Isles
7.6 out of 10, Good, (220 reviews)
"Clean room and staff was excellent "
Canada
SURINDER
The price is ₩141,381
₩182,778 total
includes taxes & fees
Feb 16 - Feb 17
Quality Inn Fort Myers Cape Coral

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
28 km from Sanibel Isles
8.0 out of 10, Very Good, (1,589 reviews)
"Good room for a fair price in a good location "
United States
John
The price is ₩144,445
₩161,057 total
includes taxes & fees
Feb 12 - Feb 13
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
10.3 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,217 reviews)
"Nice place to stay"
United States
Denise
The price is ₩466,287
₩552,547 total
includes taxes & fees
Feb 11 - Feb 12
Lani Kai Beachfront Resort

Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
25.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,140 reviews)
"The staff was friendly and always acknowledged me. The room was clean and comfortable,"
United States
Jennifer
The price is ₩195,672
₩218,175 total
includes taxes & fees
Feb 15 - Feb 16
Best Western Fort Myers Inn & Suites

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
21.9 km from Sanibel Isles
7.6 out of 10, Good, (1,178 reviews)
"Clean room easy check in and out. "
United States
Erin
The price is ₩176,515
₩196,814 total
includes taxes & fees
Feb 12 - Feb 13
Americas Best Value Inn Ft. Myers

Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
27.7 km from Sanibel Isles
8.8 out of 10, Excellent, (1,125 reviews)
"Always a great stay here. "
United States
Kirk
The price is ₩221,920
₩247,441 total
includes taxes & fees
Feb 15 - Feb 16
Comfort Inn & Suites Fort Myers Airport

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
12.1 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,006 reviews)
"Very clean & friendly staff. "
United States
denise
The price is ₩242,949
₩270,888 total
includes taxes & fees
Feb 22 - Feb 23
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
10.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1,007 reviews)
"Great stay"
United States
Andrea
The price is ₩347,981
₩388,002 total
includes taxes & fees
Mar 7 - Mar 8
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd
2.5 star property
25.7 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,008 reviews)
"Great place to stay, will be back!"
United States
Douglas
The price is ₩254,617
₩283,897 total
includes taxes & fees
Mar 1 - Mar 2
Hampton Inn & Suites Fort Myers - Colonial Blvd

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
18.3 km from Sanibel Isles
8.8 out of 10, Excellent, (274 reviews)
"The property was super cute and clean! It also had just about anything you could need!"
United States
Wyatt
The price is ₩183,090
₩313,931 total
includes taxes & fees
Feb 12 - Feb 13
Matlacha Tiny Village

Quality Suites Fort Myers I-75

Quality Suites Fort Myers I-75
2.5 star property
27 km from Sanibel Isles
8.2 out of 10, Very Good, (1,006 reviews)
"Clean rooms and friendly staff"
United States
Krystal
The price is ₩193,775
₩216,058 total
includes taxes & fees
Mar 1 - Mar 2
Quality Suites Fort Myers I-75

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
3.0 star property
29.4 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,312 reviews)
"very nice stay, staff was friendly and excellent"
United States
Gregory
The price is ₩282,762
₩315,280 total
includes taxes & fees
Mar 9 - Mar 10
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

Allure Suites

Allure Suites
3.0 star property
17.9 km from Sanibel Isles
7.8 out of 10, Good, (1,014 reviews)
"The room was very clean, spacious and the kitchenette was nice! The staff was also very helpful and really nice!!"
United States
Kristin
The price is ₩167,790
₩187,086 total
includes taxes & fees
Feb 20 - Feb 21
Allure Suites

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
15.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1,227 reviews)
"Nice room, great tiki bar and pool area, and friendly staff."
United States
Jason
The price is ₩240,742
₩268,428 total
includes taxes & fees
Mar 6 - Mar 7
Dolphin Key Resort

Best Western Fort Myers Waterfront

Best Western Fort Myers Waterfront
3.0 star property
27.5 km from Sanibel Isles
7.4 out of 10, Good, (1,011 reviews)
"Clean room, staff, view over river"
United States
Tracy
The price is ₩221,993
₩247,522 total
includes taxes & fees
Feb 15 - Feb 16
Best Western Fort Myers Waterfront

Travelodge by Wyndham Fort Myers Airport

Travelodge by Wyndham Fort Myers Airport
2.0 star property
27 km from Sanibel Isles
7.4 out of 10, Good, (1,005 reviews)
"Room was spotless and the staff was very nice and friendly "
United States
Ann marie
The price is ₩133,037
₩148,336 total
includes taxes & fees
Mar 1 - Mar 2
Travelodge by Wyndham Fort Myers Airport

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
27.6 km from Sanibel Isles
9.6 out of 10, Exceptional, (1,016 reviews)
"Nice room, nice staff, great airport shuttle "
United States
Amy
The price is ₩259,709
₩289,576 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites Fort Myers Airport by IHG

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
20.9 km from Sanibel Isles
8.8 out of 10, Excellent, (1,009 reviews)
"Great stay "
United States
Brandon
The price is ₩267,996
₩298,816 total
includes taxes & fees
Feb 16 - Feb 17
Doubletree by Hilton Fort Myers at Bell Tower Shops

Trianon Bonita Bay

Trianon Bonita Bay
3.5 star property
27.6 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,746 reviews)
"Clean and comfy rooms and staff was great"
United States
Jarrett
The price is ₩353,234
₩393,855 total
includes taxes & fees
Mar 9 - Mar 10
Trianon Bonita Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas and neighborhoods for the activities you enjoy most.

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travelers to the Sanibel Isles neighborhood in Sanibel will be sure to enjoy their stay.
How many hotels will I find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 7 hotels and other accommodations in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best deals available in Sanibel Isles.
Where can I learn more about changing or cancelling my trip to Sanibel Isles?
To access more information about picking new dates or cancelling your trip to Sanibel Isles, go to https://www.expedia.com/service/.
What is there to do in this Sanibel neighborhood?
Woodring Point, Woodring Beach, and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Periwinkle Way are also worth a visit when you're out sightseeing in Sanibel.