Photo by Alicia Panta

Find hotels in Santa Ana, Cusco

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Ana hotels

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1004)
"great hotel"
United States
Rodolfo
The price is ₩163,138
₩179,452 total
Jan 8 - Jan 9, 2026
Hilton Garden Inn Cusco

Hotel Cusco Pacha Inti

Hotel Cusco Pacha Inti
3.0 star property
Santa Ana
6.0 out of 10, (1)
"El hotel cumple con sus funciones, sin embargo es complicado el tema de la regadera, considero es un punto que pueden mejorar. El hotel no está alejado del centro pero está en una zona no tan cómoda de llegar, ni siquiera los autos tienen accedió tan fácil. El personal es muy atento y amable, sin embargo tuve que pagar dos veces la reservación porque a ellos "no se les reflejaba" siendo que ellos mismos confirmaron que tienen problemas con expedis y Booking y a pesar de que les mostré en mi...
Mexico
CR
The price is ₩41,808
₩41,808 total
Dec 30 - Dec 31
Hotel Cusco Pacha Inti

ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
The price is ₩72,083
₩72,083 total
Dec 30 - Dec 31
ZEVEN HOUSE - CUSCO APARTMENT

Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (12)
"A pleasant place to visit Cuzco"
France
Michel
Centro by Casa Andina Cusco Saphi

Munay Cusco

Munay Cusco
2.0 star property
Santa Ana
The price is ₩25,950
₩25,950 total
Dec 30 - Dec 31
Munay Cusco

Santa Ana Departamentos

Santa Ana Departamentos
2.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Grand appartement à 10 min à pied de la place des Armes. Il y a également un bus qui s'arrête devant le portail. Nous sommes toujours descendus à pied et remontés en navette. Eau chaude, appartement un peu froid mais pas insurmontable. Accueil très sympathique et agréable de la part des propriétaires, n'hésitez pas à leur demander conseils ou de l'aide ils feront tout pour vous aider. Nous avons passé un excellent séjour grâce à eux."
France
Mélissa
Santa Ana Departamentos

Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana
3.0 star property
Santa Ana
The price is ₩47,086
₩47,086 total
Dec 30 - Dec 31
Hotel El Mirador de Santa Ana

Munay Ñusta Cusco

Munay Ñusta Cusco
3.0 star property
Santa Ana
9.6 out of 10, Exceptional, (4)
"Very nice property"
United States
Arthur
The price is ₩64,875
₩71,362 total
Jan 7 - Jan 8, 2026
Munay Ñusta Cusco

Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (500)
"Great place ! "
United States
Roger
Tierra Viva Cusco Saphi

Anata Hostel

Anata Hostel
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (21)
"Great location, staff incredible!"
Canada
christiane
The price is ₩34,695
₩34,695 total
Jan 2 - Jan 3, 2026
Anata Hostel

Casa Karmenka

Casa Karmenka
2.5 star property
Santa Ana
Casa Karmenka

Hotel Mamasara

Hotel Mamasara
3.0 star property
Santa Ana
8.4 out of 10, Very Good, (18)
"It was nice"
United States
Alexander
Hotel Mamasara

HOSTAL LA RASA

HOSTAL LA RASA
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (2)
"Accueil très agréable !"
France
Lia
The price is ₩28,545
₩28,545 total
Jan 2 - Jan 3, 2026
HOSTAL LA RASA

Tucan Hostel

Tucan Hostel
2.0 star property
Santa Ana
8.4 out of 10, Very Good, (14)
"We found this hostel to be a very special place, filled with wonderfully helpful and pleasant folks. We would highly recommend a stay."
United States
Anonymous traveler
The price is ₩44,691
₩44,691 total
Jan 3 - Jan 4, 2026
Tucan Hostel

LP Los Portales Hotel Cusco

LP Los Portales Hotel Cusco
3.5 star property
Cusco Historic Center, 1.4 km from Santa Ana
9.4 out of 10, Exceptional, (782)
"Clean sheets and bed comfy pillows clean bath tub with jets. We had a great time with my husband. Room was quiet and affordable. Stuff was very nice and helpful. Free tea anytime and room service was nice. Soup is instant one so pass that but main dishes were good"
United States
Sinem
The price is ₩86,500
₩95,150 total
Jan 17 - Jan 18, 2026
LP Los Portales Hotel Cusco

Union Hotel Cusco

Union Hotel Cusco
3.5 star property
Cusco Historic Center, 0.5 km from Santa Ana
9.2 out of 10, Wonderful, (1001)
"Love this place, all the staff was very friendly, we love KIKI"
United States
Jesus Daniel
Union Hotel Cusco

Abittare Hotels

Abittare Hotels
3.0 star property
Cusco Historic Center, 1.2 km from Santa Ana
9.0 out of 10, Wonderful, (377)
"Good, clean and nice hotel "
United States
Silvana
The price is ₩97,571
₩107,328 total
Jan 29 - Jan 30, 2026
Abittare Hotels

Ureta Hotel

Ureta Hotel
3.5 star property
Rosaspata, 2.3 km from Santa Ana
9.6 out of 10, Exceptional, (648)
"Rooms were clean, breakfasts were great and the staff was amazing "
United States
jeremiah
The price is ₩76,120
₩76,120 total
Jan 4 - Jan 5, 2026
Ureta Hotel

Sonesta Hotel Cusco

Sonesta Hotel Cusco
4.0 star property
Cusco Historic Center, 1.7 km from Santa Ana
9.6 out of 10, Exceptional, (1010)
"Nice hotel with great breakfast "
United States
Jenny
The price is ₩229,224
₩252,146 total
Jan 7 - Jan 8, 2026
Sonesta Hotel Cusco

Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco
4.0 star property
Cusco Historic Center, 0.5 km from Santa Ana
9.4 out of 10, Exceptional, (1116)
"Very nice hotel in a beautiful historic building "
United States
Zdenek
The price is ₩183,667
₩202,034 total
Jan 8 - Jan 9, 2026
Wyndham Costa del Sol Cusco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Cusco Historic Center

Explore museums like Museo de Arte Precolombino and savor fusion and neo-Andean cuisine at local restaurants. Stroll through the artisan-filled San Blas neighborhood for a picturesque shopping experience.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Plaza Sán Cristobal and Museo de Arte Precolombino.

Santa Monica

Santa Monica might not have many top sights, but Real Plaza Cusco and Ttio Market are two attractions nearby that you can check out.

Santiago

When in Santiago, you can plan a visit to Ttio Market and Santiago Plaza, some noteworthy sights in the nearby area.

Top Santa Ana Hotel Reviews

Frequently asked questions

What is Santa Ana like?
Travelers to Cusco's Santa Ana neighborhood will be sure to enjoy a stay in this neighborhood.
What's the best accommodation in Santa Ana?
Based on Expedia customer reviews, Hilton Garden Inn Cusco is the highest ranked property in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant. Another favorite option in the neighborhood is Tierra Viva Cusco Saphi.
How many hotels should I expect to find in the Santa Ana area?
If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 41 Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, go to https://www.expedia.com/service/.
What can I see and do in this Cusco neighborhood?
A few places to visit in the area around Santa Ana include Museo Irq'i Yachay, Museo de Plantas Sagradas Magicas y Medicinales, and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.