Find Luxury Hotels in Santa Cruz

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz Luxury Hotels

Our top choices for Santa Cruz luxury hotels

Reception

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (420 reviews)
"Rooms were very clean and service was excellent "
United States
JESUS
The price is ₩187,182
₩187,182 total
Apr 6 - Apr 7
Camino Real Hotel
Exterior detail

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (152 reviews)
"Yes! Room was spotless. The staff are very patient and professional. "
United States
Pluetina
The price is ₩146,869
₩146,869 total
Mar 10 - Mar 11
TRYP by Wyndham Santa Cruz
Outdoor pool, pool umbrellas, sun loungers

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (218 reviews)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ₩157,625
₩157,625 total
Mar 27 - Mar 28
Marriott Santa Cruz de la Sierra Hotel
Lounge

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (264 reviews)
"Nice hotel "
United States
Narciso Lorenzo
The price is ₩109,188
₩109,188 total
Mar 12 - Mar 13
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Lobby sitting area

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (109 reviews)
"Luxurious hotel,very chic and beautiful."
United States
Cristhian
The price is ₩155,771
₩155,771 total
Mar 24 - Mar 25
Novotel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent
"Yes"
Patzy 3-night trip
Posted 1 day ago
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Frequently asked questions

Are you looking for a luxury hotel for your Santa Cruz vacation?
Travel to Santa Cruz (SRZ-El Trompillo) Airport or Santa Cruz (VVI-Viru Viru Intl.) Airport, and then treat yourself to a stay at one of 7 Santa Cruz luxury hotels. Santa Cruz has some interesting things to see and do including Plaza 24 de Septiembre and Artecampo, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are two other upscale options for your stay.
How many luxury hotels will I find in Santa Cruz?
Lie in the lap of luxury during your getaway to Santa Cruz in one of Expedia's 7 luxury hotels.
When can I expect good weather in Santa Cruz?
Planning for the weather is a good way to make your trip to Santa Cruz relaxing and enjoyable, especially when you're splurging. The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.
What's there to see and do in Santa Cruz?
Enjoy all that Santa Cruz has to offer when you visit Plaza 24 de Septiembre, Artecampo, and Ramon Tahuichi Aguilera Stadium. If you have a little extra time during your trip, you might want to make a stop at Cine Center and Santa Cruz Zoo.
How can I get around Santa Cruz?
It's easier to get around town comfortably when you know your options. To see more of the larger area, hop on a train at Santa Cruz de la Sierra Station.