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Feb 21 - Feb 22
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Our top choices for Santa Isabel hotels

Aerial view

Private Ocean-Front Cabin with private bathroom on San Blas Island

Private Ocean-Front Cabin with private bathroom on San Blas Island
2.0 star property
Narganá
Private Ocean-Front Cabin with private bathroom on San Blas Island
Property grounds

Cabins on paradise San Blas island

Cabins on paradise San Blas island
2.0 star property
Narganá
Cabins on paradise San Blas island
Exterior

Cocoloco - Catamaran Lagoon 52F SAN BLAS

Cocoloco - Catamaran Lagoon 52F SAN BLAS
3.0 star property
Narganá
The price is ₩2,839,951
₩3,123,946 total
includes taxes & fees
Mar 4 - Mar 5
Cocoloco - Catamaran Lagoon 52F SAN BLAS
Economy Bungalow | Bed sheets

Trips Guna Yala

Trips Guna Yala
2.0 star property
Narganá
The price is ₩149,689
₩347,611 total
includes taxes & fees
Feb 22 - Feb 23
Trips Guna Yala
Exterior

Cabañas Nalunega San Blas

Cabañas Nalunega San Blas
2.0 star property
Narganá
Cabañas Nalunega San Blas
View from property

Cabañas Isla Nubesidub San Blas

Cabañas Isla Nubesidub San Blas
2.0 star property
Narganá
Cabañas Isla Nubesidub San Blas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Isabel

Explore pristine beaches along Santa Isabel's coastline where local fishermen can take you to nearby coral reefs for snorkeling. Hike through lush rainforest trails to spot colorful birds, then visit the town's central plaza where vendors sell fresh tropical fruits and handcrafted souvenirs.

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Scenic Coiba Island Aerial View

Top Santa Isabel Hotel Reviews

More cheap stays in Santa Isabel

San Blas Paradise Private Cabins on Shipwreck Island - meals included

San Blas Paradise Private Cabins on Shipwreck Island - meals included

Perro Island Narganá Guna Yala
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Frequently asked questions

What's the best place to stay in Santa Isabel?
Located 17 mi (27.3 km) from the heart of Santa Isabel, Cocoloco - Catamaran Lagoon 52F SAN BLAS is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Private Ocean-Front Cabin with private bathroom on San Blas Island and Trips Guna Yala. See all available top hotels, or vacation rentals in Santa Isabel.
If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Isabel.
Where can I learn more about changing or cancelling my trip to Santa Isabel?
For additional details about rescheduling or cancelling your trip to Santa Isabel, go to https://www.expedia.com/service/.
What's the best place to stay near Tocumen International Airport (PTY)?
Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.
What is staying in Santa Isabel like?
Visitors can enjoy all that Santa Isabel has to offer including its parks. There are 41 hotels and other accommodations in the surrounding area. Find out more about Santa Isabel.
What are the top places to visit in Santa Isabel?
Places to visit in the wider area include Chagres National Park, Museum, and Porvenir Museum. Check out what more to see and do in Expedia's Santa Isabel guide.
What's the seasonal weather like in Santa Isabel?
The hottest months are usually June and September with an average temp of 80°F, while the coldest months are February and March with an average of 78°F. The rainiest months in Santa Isabel are October, August, July, and November, with each month seeing an average of 12 inches of rainfall.