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Check prices for these dates

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Jul 31 - Aug 2
Next weekend
Aug 7 - Aug 9

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Our top choices for Santa Maria hotels

Property entrance

1. DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (645 reviews)
"Nice, clean simple, family run hotel with good transportation."
United States
Gerald
The price is ₩51,840
₩53,280 total
Aug 12 - Aug 13
DC Suites Aeropuerto
Outdoor pool, sun loungers

2. Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (48 reviews)
"Breakfasts were excellent. Staff went out of their way to accommodate late arrival. "
Canada
Kimberly
The price is ₩162,000
₩179,640 total
Aug 1 - Aug 2
Iguanazu Bed & Breakfast
Front of property

3. Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (181 reviews)
"Love the breakfast menu and security."
United States
Marcela
The price is ₩151,632
₩153,072 total
Aug 9 - Aug 10
Luxva Hotel Boutique
Terrace/patio

4. Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.6 out of 10, Excellent, (277 reviews)
"Very clean and comfortable rooms. The staff was very friendly and they're all fluent in English and Spanish. Breakfast in the restaurant was also delicious."
United States
Myna-Maria
The price is ₩89,813
₩100,959 total
Aug 22 - Aug 23
Hotel Puerto Pacifico Guayaquil Airport
Children's activities

5. Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,002 reviews)
"Definitely the best and friendliest Hotel in Guayaquil!"
United States
Josef Walter
The price is ₩129,600
₩146,160 total
Aug 9 - Aug 10
Oro Verde Guayaquil
Rooftop bar, alfresco dining, open daily

6. Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"Best hotel and great location food amazing"
United States
Giselle
The price is ₩115,344
₩129,038 total
Aug 9 - Aug 10
Wyndham Garden Guayaquil
Lobby

7. Hotel Palace Guayaquil

Hotel Palace Guayaquil
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (941 reviews)
"I like it all real clean real good stuff and was placent"
United States
moti
The price is ₩84,781
₩95,423 total
Aug 8 - Aug 9
Hotel Palace Guayaquil
Lobby

8. Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,002 reviews)
"Great locations and wonderful staff.!!"
Canada
Carlos
The price is ₩115,200
₩128,880 total
Aug 9 - Aug 10
Courtyard by Marriott Guayaquil
Comfort Double Room | In-room safe, desk, WiFi (free), bed sheets

9. Hotel GH Alexander

Hotel GH Alexander
3.5 star property
Rocafuerte, 7.3 km from Santa Maria
8.6 out of 10, Excellent, (43 reviews)
"Great value hot water clean friendly staff on site restaurant "
United States
Monty
The price is ₩43,908
₩45,348 total
Aug 3 - Aug 4
Hotel GH Alexander
Sundeck

10. Grand Hotel Guayaquil, Centro Histórico.

Grand Hotel Guayaquil, Centro Histórico.
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"I enjoyed everything about this hotel."
United States
Maria Dorila
The price is ₩100,751
₩112,990 total
Aug 29 - Aug 30
Grand Hotel Guayaquil, Centro Histórico.
Property entrance

11. Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (712 reviews)
"The room was clean, the staff is great, and the food is good too. The food is very expensive, and there is a bad smell coming from the bathroom at night; it seems like something is wrong with the sewer"
United States
Maria
The price is ₩129,600
₩146,160 total
Aug 9 - Aug 10
Radisson Hotel Guayaquil
Cafe

12. Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,000 reviews)
"Great overnight stay. Lovely staff, excellent room and amenities and a great breakfast!"
Australia
Peter
The price is ₩145,440
₩163,584 total
Aug 9 - Aug 10
Holiday Inn Guayaquil Airport by IHG
32-inch Smart TV with digital channels, first-run movies

13. Departamentos en la Garzota

Departamentos en la Garzota
4.5 star property
Garzota, 3.9 km from Santa Maria
The price is ₩43,200
₩45,360 total
Aug 8 - Aug 9
Departamentos en la Garzota
Property grounds

14. Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 4.6 km from Santa Maria
10.0 out of 10, Exceptional, (10 reviews)
"Very convenient to airport and local shopping. Outstanding service and price."
United States
Scottie
The price is ₩100,598
₩102,038 total
Aug 4 - Aug 5
Hostal Macaw
Terrace/patio

15. Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (58 reviews)
"Clean"
United States
Scott E
The price is ₩41,472
₩41,472 total
Aug 17 - Aug 18
Casa Serena
Food and drink

16. Hotel Patrimonial by Greenfield

Hotel Patrimonial by Greenfield
3.5 star property
Downtown Guayaquil, 7.5 km from Santa Maria
8.4 out of 10, Very Good, (157 reviews)
"The pool was enjoyable but going during the day so the water isn’t as cold."
United States
Julio
The price is ₩63,922
₩65,365 total
Aug 1 - Aug 2
Hotel Patrimonial by Greenfield
Outdoor pool

17. Tropical Inn

Tropical Inn
2.0 star property
9.2 km from Santa Maria
8.0 out of 10, Very Good, (18 reviews)
"for the price was good"
United States
Rosa
The price is ₩33,696
₩55,296 total
Aug 30 - Aug 31
Tropical Inn
2 bars/lounges, lobby lounge

18. Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"Nice river view, clean room, nice staff and breakfast buffet great!!!"
United States
Nancy
The price is ₩144,116
₩162,135 total
Aug 23 - Aug 24
Wyndham Guayaquil Puerto Santa Ana
Breakfast meal

19. MC Suites

MC Suites
3.5 star property
Kennedy, 4.4 km from Santa Maria
8.2 out of 10, Very Good, (138 reviews)
"It is good for a day or 2 close to airport. Clean and staff excellent "
United States
Eulises
The price is ₩64,268
₩65,711 total
Aug 1 - Aug 2
MC Suites
Lobby

20. Hotel GH Galeria

Hotel GH Galeria
3.5 star property
Downtown Guayaquil, 6.9 km from Santa Maria
8.4 out of 10, Very Good, (411 reviews)
"So so experience."
United States
Daniel
The price is ₩84,859
₩95,505 total
Aug 3 - Aug 4
Hotel GH Galeria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.
A row of colorful colonial buildings with balconies and wooden shutters.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

An iguana on green grass.
Photo by Botak Jon
Open Photo by Botak Jon

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Sports Federation of Guayas and Central Market while you're in town.

A densely packed urban area with numerous buildings and a prominent tower on a hill.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Botanical Garden while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

A cityscape with colorful buildings, a prominent church, and a hill with residential structures.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

A golden statue of two figures forming a heart shape on a paved area with a modern building in the background.
Photo by Botak Jon
Open Photo by Botak Jon

Simón Bolívar

Simón Bolívar might not have many top sights, but Mall del Sol Shopping Center and San Marino Mall are two attractions nearby that you can check out.

Top Santa Maria Hotel Reviews

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil

10/10 Excellent
"The room was clean, the staff is great, and the food is good too. The food is very expensive, and there is a bad smell coming from the bathroom at night; it seems like something is wrong with the sewer"
Maria 3-night trip
Posted 7 hours ago
Radisson Hotel Guayaquil

Frequently asked questions

What is Santa Maria like?
Travelers are sure to enjoy a stay in Guayaquil's Santa Maria neighborhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For more information about changing or cancelling your trip to Santa Maria, go to https://www.expedia.com/service/.
What can I see and do in this Guayaquil neighborhood?
Salón de Eventos Rubi, City Mall, and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.