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Our top choices for Santa Maria hotels

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
5.6 km from Santa Maria
The price is ₩78,128
₩79,599 total
May 5 - May 6
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (47 reviews)
"Swimming pool"
United States
Paulus
The price is ₩86,073
₩96,152 total
May 7 - May 8
Iguanazu Bed & Breakfast

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
9.8 km from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ₩70,624
₩70,624 total
May 5 - May 6
Hotel La Ria Durán

Hotel del Parque

Hotel del Parque
4.5 star property
7 km from Santa Maria
9.8 out of 10, Exceptional, (112 reviews)
"Breakfast excellent"
United States
Priscilla
The price is ₩631,205
₩694,325 total
May 10 - May 11
Hotel del Parque

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,001 reviews)
"Excellent service, comfortable beds, quiet, and good meals. "
Australia
Gareth
The price is ₩144,191
₩162,288 total
May 24 - May 25
Holiday Inn Guayaquil Airport by IHG

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"great safe place will be back "
United States
Tracy
The price is ₩146,987
₩165,364 total
May 16 - May 17
Wyndham Guayaquil Puerto Santa Ana

NCG Suite 5

NCG Suite 5
2.5 star property
4.3 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"loved everything "
United States
Betty
The price is ₩51,497
₩51,497 total
May 22 - May 23
NCG Suite 5

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.6 out of 10, Exceptional, (1,004 reviews)
"Room clean, airport shuttle a nice bonus"
Canada
LESLIE
The price is ₩116,236
₩131,538 total
May 10 - May 11
Oro Verde Guayaquil

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 7.9 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ₩459,058
₩511,217 total
May 6 - May 7
Hotel Río Guayas by Art Hotels Ecuador

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 4.2 km from Santa Maria
8.6 out of 10, Excellent, (907 reviews)
"Overall experience would give it a 4.5 stars. Staff for the most part very friendly and helpful. Food was ok, clean rooms, exec lounge was nice to have! Would recommend!"
United States
Alex
The price is ₩143,823
₩161,883 total
May 24 - May 25
Hilton Colon Guayaquil

Casa Veranda

Casa Veranda
2.5 star property
8.9 km from Santa Maria
The price is ₩46,347
₩46,347 total
May 5 - May 6
Casa Veranda

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 4.6 km from Santa Maria
10.0 out of 10, Exceptional, (9 reviews)
"Contento por haber reservado una noche de estadía en esta gran propiedad, desde la bienvenida, un ambiente cálido y cordial, la habitación cómoda, limpia y con A/C funcionando perfectamente, el desayuno vino incluido en la tarifa. La zona donde esta ubicada la hostal, muy segura y cerca de todo, accesible en uber y en una zona muy central para mis actividades. Volveré sin duda y tomare mas dias acá."
Ecuador
SANTIAGO
The price is ₩102,788
₩104,259 total
May 5 - May 6
Hostal Macaw

NCG Suite 3

NCG Suite 3
2.5 star property
4.4 km from Santa Maria
The price is ₩60,914
₩62,385 total
May 5 - May 6
NCG Suite 3

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (180 reviews)
"Clean room, staff, location"
United States
Veronica
The price is ₩125,800
₩127,271 total
May 6 - May 7
Luxva Hotel Boutique

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (642 reviews)
"The food was delicious the staff was very friendly I recommend this hotel "
Canada
Monica
The price is ₩161,847
₩189,802 total
May 8 - May 9
Sheraton Guayaquil Hotel

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,001 reviews)
"The staff service was very friendly, and the hotel’s location is excellent. Everything was very clean, and the rooms had a pleasant scent. "
United States
E .Veronica
The price is ₩132,788
₩149,738 total
May 16 - May 17
TRYP by Wyndham Guayaquil Airport

Doubletree By Hilton Guayaquil

Doubletree By Hilton Guayaquil
5.0 star property
Downtown Guayaquil, 8.1 km from Santa Maria
9.0 out of 10, Wonderful, (90 reviews)
"Excellent in every aspect. Friendly staff. Comfortable rooms. "
United States
Juan
The price is ₩101,302
₩118,796 total
May 30 - May 31
Doubletree By Hilton Guayaquil

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (685 reviews)
"Great staff and service "
United States
Jason
The price is ₩147,134
₩165,525 total
May 8 - May 9
Radisson Hotel Guayaquil

NCG Suite Samanes 2

NCG Suite Samanes 2
3.0 star property
4.3 km from Santa Maria
8.8 out of 10, Excellent, (3 reviews)
"Propiedad segura, ordenada, limpia y tranquila."
Mexico
Shirley
The price is ₩47,671
₩49,142 total
May 5 - May 6
NCG Suite Samanes 2

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 7.8 km from Santa Maria
8.8 out of 10, Excellent, (138 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ₩82,542
₩92,267 total
May 6 - May 7
Mansión del Río
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to World Trade Center or San Marino Mall.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travelers are sure to enjoy a stay in Guayaquil's Santa Maria neighborhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For more information about changing or cancelling your trip to Santa Maria, go to https://www.expedia.com/service/.
What can I see and do in this Guayaquil neighborhood?
Salón de Eventos Rubi, City Mall, and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.