Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

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Check availability on Santee Family Hotels

Tonight
Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Santee family-friendly hotels

Exterior
Free toiletries, hair dryer, towels, soap
Lobby
Free daily continental breakfast

1. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family vacation paradise with an outdoor pool, fitness center, and quiet, pet-friendly atmosphere for your whole family.
₩152,609
₩169,396 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Plus Santee Inn
Property amenity
Lobby lounge
Free daily buffet breakfast
Reception

2. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
₩178,971
₩198,658 total
includes taxes & fees
Sep 15 - Sep 16
Fairfield Inn & Suites by Marriott Santee
Seasonal outdoor pool
Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes
Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall) | Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

3. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
₩139,683
₩155,049 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites Santee
In-room safe, iron/ironing board, WiFi (free), alarm clocks
Bathtub, free toiletries, hair dryer, towels
Free daily continental breakfast
Business center

4. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
₩88,381
₩98,103 total
includes taxes & fees
Aug 30 - Aug 31
Travelodge by Wyndham Santee
Desk, iron/ironing board, WiFi (free), alarm clocks
Lobby
Desk, iron/ironing board, WiFi (free), alarm clocks
Desk, iron/ironing board, WiFi (free), alarm clocks

5. Econo Lodge Santee

Econo Lodge Santee
Santee
₩79,708
₩88,478 total
includes taxes & fees
Sep 27 - Sep 28
Econo Lodge Santee
Free daily continental breakfast
Lobby
Combined shower/tub, hair dryer, towels
Front of property

6. Peach Tree Inn

Peach Tree Inn
St. George
₩101,914
₩110,067 total
includes taxes & fees
Aug 29 - Aug 30
Peach Tree Inn
Reception
Lobby lounge
Combined shower/tub, hair dryer, towels
Exterior

7. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
₩80,773
₩89,659 total
includes taxes & fees
Sep 3 - Sep 4
Red Roof Inn Orangeburg
Breakfast area
Combined shower/tub, hair dryer, towels
Desk, iron/ironing board (on request), WiFi (free), bed sheets
Reception

8. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
Orangeburg
₩109,095
₩121,095 total
includes taxes & fees
Aug 30 - Aug 31
Travelodge by Wyndham Orangeburg
Exterior
Exterior
Exterior
Property amenity

9. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
Orangeburg
  • Family-friendly retreat with scenic poolside play, planetarium exploration, and delicious breakfast buffet served daily.
₩147,762
₩164,016 total
includes taxes & fees
Sep 27 - Sep 28
Holiday Inn Express & Suites Orangeburg by IHG
View all properties

Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Santee Hotel Reviews

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Clean room"
Mohammad 2-night trip
Posted 2 days ago
Comfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Excellent"
Andrew 1-night trip
Posted 5 days ago
Hampton Inn Santee-I-95
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

8/10 Good
"Friendly front desk receptionist"
Derrick 1-night trip
Posted 7 days ago
Travelodge by Wyndham Orangeburg
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

8/10 Good
"The staff was very helpful and respectful."
Mark 4-night trip
Posted 10 days ago
Travelodge by Wyndham Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 2 weeks ago
Ramada by Wyndham Santee I-95

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Edisto Memorial Gardens. Make sure you have lots of time for activities like Congaree National Park and Santee National Wildlife Refuge.

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