An aerial view of a coastal landscape with a dam, farmland, and dense forests.

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Check availability on Santee Family Hotels

Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Santee family-friendly hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A reception desk with a wooden panel wall and a circular decorative piece above it.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
₩185,003
₩205,353 total
includes taxes & fees
Oct 21 - Oct 22
Fairfield Inn & Suites by Marriott Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".
A modern bathroom with a large sink, a shower with a glass door, and a towel rack.
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
  • Family fun for everyone at this Santee hotel with a seasonal pool, free breakfast, and kid-friendly extras.
₩158,065
₩175,453 total
includes taxes & fees
Nov 3 - Nov 4
Hampton Inn Santee-I-95
A modern lounge area with a mural, pool table, comfortable seating, and a large TV screen.
Business center
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A hotel room with two beds, a desk, and a large window with a view.

3. Tru By Hilton Santee

Tru By Hilton Santee
Santee
₩135,920
₩150,871 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Santee
A hotel entrance with a sign reading "Best Western PLISS."
Bathroom
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

4. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family vacation paradise with an outdoor pool, fitness center, and quiet, pet-friendly atmosphere for your whole family.
₩186,071
₩206,539 total
includes taxes & fees
Oct 21 - Oct 22
Best Western Plus Santee Inn
A swimming pool with a 5 ft depth marker, surrounded by lounge chairs and a building with multiple windows.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.
A bathroom with a dark granite countertop, a white sink, a large mirror, a toilet, and a shower with a glass door.

5. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
₩138,944
₩154,227 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Santee
A water park with a pool, slides, and umbrellas.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A modern lounge area with seating, tables, and a fireplace.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
  • Family adventure awaits at this Holiday Inn with an indoor pool, premium TV channels, and water sports equipment nearby.
₩134,375
₩149,155 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Santee by IHG
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A motel with a brick facade, a covered entrance, and a satellite dish.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.

7. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
₩86,762
₩96,304 total
includes taxes & fees
Oct 19 - Oct 20
Travelodge by Wyndham Santee
A modern bathroom with a sink, toilet, and shower area.
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with large windows.
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.

8. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
₩85,094
₩94,455 total
includes taxes & fees
Oct 26 - Oct 27
Super 8 by Wyndham Santee/I-95
A two-story building with a flat roof and a central entrance.
A bathroom with a shower, toilet, and a towel rack.
A hotel room with a bed, bedside lamps, a nightstand, a dresser, and a bathroom visible through an open door.
A spacious kitchen with a dining area, wooden flooring, and a Red Roof Inn sign.

9. Red Roof Inn Santee

Red Roof Inn Santee
Santee
₩84,081
₩93,330 total
includes taxes & fees
Oct 18 - Oct 19
Red Roof Inn Santee
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.
A spacious kitchen with a central island, a chandelier, and a sign indicating 'Quality' on the wall.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
₩73,100
₩87,846 total
includes taxes & fees
Nov 4 - Nov 5
Quality Inn & Suites Santee I-95
View all properties

Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Santee

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A reception desk with a wooden panel wall and a circular decorative piece above it.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
₩185,003
₩205,353 total
includes taxes & fees
Oct 21 - Oct 22
Fairfield Inn & Suites by Marriott Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".
A gym with treadmills, weight machines, and a wall of dumbbells.
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
₩158,119
₩175,512 total
includes taxes & fees
Nov 5 - Nov 6
Hampton Inn Santee-I-95
A hotel entrance with a sign reading "Best Western PLISS."
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
₩186,071
₩206,539 total
includes taxes & fees
Oct 21 - Oct 22
Best Western Plus Santee Inn
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."
A modern lobby with a blue sofa, teal chairs, and a wooden table.
A hotel room with two beds, a desk, and a large window with a view.

Tru By Hilton Santee

Tru By Hilton Santee
Santee
₩135,920
₩150,871 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Santee
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
₩138,944
₩154,227 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Santee
A water park with a pool, slides, and umbrellas.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A modern lounge area with seating, tables, and a fireplace.

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
₩134,375
₩149,155 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Santee by IHG
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A motel with a brick facade, a covered entrance, and a satellite dish.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A bathroom with a granite countertop, a sink, a mirror, and a light fixture above the mirror.

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
₩86,762
₩96,304 total
includes taxes & fees
Oct 19 - Oct 20
Travelodge by Wyndham Santee
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A reception area with a marble counter, a television, and a logo for 'Superstart breakfast'.
A two-story building with a beige facade, large windows, and a central entrance.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with large windows.

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
₩85,094
₩94,455 total
includes taxes & fees
Oct 26 - Oct 27
Super 8 by Wyndham Santee/I-95
A two-story building with a flat roof and a central entrance.
A hotel room with a large bed, a desk, a television, and a door.
A reception area with a wooden floor, a reception desk, and two red leather chairs.
A spacious kitchen with a dining area, wooden flooring, and a Red Roof Inn sign.

Red Roof Inn Santee

Red Roof Inn Santee
Santee
₩84,081
₩93,330 total
includes taxes & fees
Oct 18 - Oct 19
Red Roof Inn Santee
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.
A spacious kitchen with a central island, a chandelier, and a sign indicating 'Quality' on the wall.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
₩73,100
₩87,846 total
includes taxes & fees
Nov 4 - Nov 5
Quality Inn & Suites Santee I-95
View all properties

Family-friendly hotels with pools in Santee

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A reception desk with a wooden panel wall and a circular decorative piece above it.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
₩185,003
₩205,353 total
includes taxes & fees
Oct 21 - Oct 22
Fairfield Inn & Suites by Marriott Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".
A gym with treadmills, weight machines, and a wall of dumbbells.
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
₩158,119
₩175,512 total
includes taxes & fees
Nov 5 - Nov 6
Hampton Inn Santee-I-95
A hotel entrance with a sign reading "Best Western PLISS."
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
₩186,071
₩206,539 total
includes taxes & fees
Oct 21 - Oct 22
Best Western Plus Santee Inn
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."
A modern lobby with a blue sofa, teal chairs, and a wooden table.
A hotel room with two beds, a desk, and a large window with a view.

Tru By Hilton Santee

Tru By Hilton Santee
Santee
₩135,920
₩150,871 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Santee
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
₩138,944
₩154,227 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Santee
A water park with a pool, slides, and umbrellas.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A modern lounge area with seating, tables, and a fireplace.

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
₩134,375
₩149,155 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Santee by IHG
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A reception area with a marble counter, a television, and a logo for 'Superstart breakfast'.
A two-story building with a beige facade, large windows, and a central entrance.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with large windows.

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
₩85,094
₩94,455 total
includes taxes & fees
Oct 26 - Oct 27
Super 8 by Wyndham Santee/I-95
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.
A spacious kitchen with a central island, a chandelier, and a sign indicating 'Quality' on the wall.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
₩73,100
₩87,846 total
includes taxes & fees
Nov 4 - Nov 5
Quality Inn & Suites Santee I-95
Lobby
Room
A pool table area with multiple tables and chairs, a bar area with a counter and shelves, and a patterned carpet.
A gym with treadmills, an elliptical, dumbbells, and a bench.

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
Santee
₩105,716
₩117,344 total
includes taxes & fees
Oct 19 - Oct 20
Ramada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

8/10 Good
"Hotel is dated however it is perfect for an overnight traveler. Internet was intermittent at best."
Chris 1-night trip
Posted 18 hours ago
Travelodge by Wyndham Orangeburg
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

10/10 Excellent
"I like everything. And when I went to get coffee the lady cleaning in there was so nice."
Latonya 1-night trip
Posted 2 days ago
SureStay Hotel by Best Western Manning
Baymont by Wyndham Santee

Baymont by Wyndham Santee

10/10 Excellent
":)"
Robert 1-night trip
Posted 3 days ago
Baymont by Wyndham Santee
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

8/10 Good
"No hot breakfast"
Randolph 1-night trip
Posted 3 days ago
Spark by Hilton Orangeburg
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Nice bed, water was very hot which is nice, and satellite TV with tons of channels."
Robert 1-night trip
Posted 3 days ago
Travelodge by Wyndham Santee
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

10/10 Excellent
"We stayed one night but it was clean, the bed was comfortable, and the breakfast provided was very good."
Melissa 1-night trip
Posted 5 days ago
Super 8 by Wyndham, Orangeburg

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Taw Caw Creek Park. Make sure you have lots of time for activities like Congaree National Park and Santee National Wildlife Refuge.

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