Find hotels in Santee, SC from ₩91,299

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santee hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,425 reviews)
"Room were very clean and staff was very helpful. I would stay there again."
United States
Charolette
The price is ₩115,296
₩127,979 total
includes taxes & fees
Mar 1 - Mar 2
Baymont by Wyndham Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (735 reviews)
"Large, clean room, friendly staff, nice breakfast. Would stay again. Also a nice Mexican restaurant nearby for dinner. "
United States
Susan
The price is ₩147,021
₩163,193 total
includes taxes & fees
Mar 4 - Mar 5
Tru By Hilton Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,001 reviews)
"Courteous reception,clean rooms and great breakfast! Have been there many times in the last 15 years and I will return.!"
Canada
Roger
The price is ₩161,434
₩179,191 total
includes taxes & fees
Mar 1 - Mar 2
Best Western Plus Santee Inn

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,002 reviews)
"Room had everything we wanted... very clean & fresh, microwave, fridge, comfy beds. Hotel was very nice and close to everything needed."
United States
Marcia
The price is ₩180,173
₩199,993 total
includes taxes & fees
Mar 8 - Mar 9
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,001 reviews)
"Liked the size of the room, the staff and the breakfast."
United States
Virginia
The price is ₩181,945
₩201,960 total
includes taxes & fees
Mar 10 - Mar 11
Hampton Inn Santee-I-95

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,013 reviews)
"Clean rooms, nice staff, decent breakfast "
United States
Dale
The price is ₩145,796
₩161,834 total
includes taxes & fees
Mar 5 - Mar 6
Comfort Inn & Suites Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,000 reviews)
"Everything was great!"
United States
Julie
The price is ₩171,812
₩190,712 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Santee by IHG

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.0 out of 10, Good, (702 reviews)
"Nice quiet room and a delicious breakfast at a reasonable rate."
United States
Joseph B
The price is ₩90,807
₩100,796 total
includes taxes & fees
Mar 1 - Mar 2
Travelodge by Wyndham Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (477 reviews)
"Clean room but needs an exhaust fan in the bathroom "
United States
Leesa
The price is ₩78,411
₩95,023 total
includes taxes & fees
Mar 4 - Mar 5
Quality Inn & Suites Santee I-95

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (443 reviews)
"The staff was very friendly and helpful. Room was clean and beds were so comfortable. "
United States
Kathy
The price is ₩108,104
₩119,995 total
includes taxes & fees
Mar 1 - Mar 2
Super 8 by Wyndham Santee

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (645 reviews)
"A good option if traveling with pets. The hotel is clean and well maintained but dated. "
United States
Karen
The price is ₩90,794
₩100,781 total
includes taxes & fees
Mar 4 - Mar 5
Red Roof Inn Santee

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (310 reviews)
"Last minute arrangements stay was quiet and peaceful "
United States
Iasia
The price is ₩98,807
₩109,675 total
includes taxes & fees
Mar 11 - Mar 12
Econo Lodge Santee

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (551 reviews)
"The grounds and property were clean and you could tell they take pride in what they're offering."
United States
Eric
Ramada by Wyndham Santee I-95

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (728 reviews)
"Overall a great place to stay!"
United States
Troy
The price is ₩121,076
₩134,393 total
includes taxes & fees
Mar 4 - Mar 5
Fairfield Inn by Marriott Orangeburg

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (169 reviews)
"Clean rooms and pleasant staff. Could use newer towels. "
United States
Patricia
Peach Tree Inn

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,000 reviews)
"Great stay"
United States
Thomas
The price is ₩164,288
₩182,359 total
includes taxes & fees
Mar 15 - Mar 16
Tru by Hilton Orangeburg

Best Inn of Manning

Best Inn of Manning
2.5 star property
Manning
7.2 out of 10, Good, (17 reviews)
"Clean, comfortable, and efficient stay with friendly helpful staff and great value for your money."
United States
Loren
The price is ₩102,430
₩113,697 total
includes taxes & fees
Mar 1 - Mar 2
Best Inn of Manning

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1,006 reviews)
"The room was very clean, the staff were very nice and the breakfast was ok. "
United States
Samantha
The price is ₩128,283
₩142,394 total
includes taxes & fees
Mar 1 - Mar 2
SureStay Hotel by Best Western Manning

Hampton Inn Manning

Hampton Inn Manning
2.5 star property
Manning
8.4 out of 10, Very Good, (1,000 reviews)
"The room and lobby was very clean and nicely decorated. Staff was very friendly and helpful."
United States
Carey
The price is ₩171,928
₩190,840 total
includes taxes & fees
Mar 17 - Mar 18
Hampton Inn Manning

Days Inn by Wyndham St George

Days Inn by Wyndham St George
2.5 star property
St. George
7.6 out of 10, Good, (1,000 reviews)
"Clean, relaxing, friendly staff!"
United States
Smith
The price is ₩144,138
₩159,993 total
includes taxes & fees
Feb 27 - Feb 28
Days Inn by Wyndham St George
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap stays in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Hampton Inn Santee-I-95 is a favorite property for Expedia customers. This hotel offers free breakfast and free parking. Other top choices based on traveler reviews include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
Where can I learn more about changing or cancelling my trip to Santee?
For more information about updating your trip to Santee or cancelling it, click here.
What's the best budget-friendly hotel in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Santee.
What's the best hotel for a family vacation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your family trip. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are other good options for your stay. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best pet-friendly accommodation in Santee?
Baymont by Wyndham Santee is a top hotel for people traveling with their pets, and offers concierge services and free WiFi for its human guests. Other good choices for you and your pet's trip include Tru By Hilton Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
Where is the best place to stay near Santee State Park?
Baymont by Wyndham Santee is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located 3 mi (4.8 km) from Santee State Park. Other good choices within 5 miles include Best Western Plus Santee Inn and Holiday Inn Santee, an IHG Hotel.
What about the best place to stay close to Santee Outlets?
One of the top choices for your stay is Baymont by Wyndham Santee, located a short 0.4 mi (0.6 km) from Santee Outlets, and this hotel offers free breakfast and free parking. Best Western Plus Santee Inn and Fairfield Inn & Suites by Marriott Santee are two other good choices in the immediate area.
What's the best golf hotel in Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodations with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast, and free WiFi. Quality Inn & Suites Santee I-95 is another choice with an onsite pool. View all hotels with pools in Santee.
What's the best place to stay near Columbia Metropolitan Airport (CAE)?
Country Inn & Suites by Radisson, Columbia Airport, SC is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 1.7 mi (2.8 km) from Columbia Metropolitan Airport. Other places to stay close to the airport are Sleep Inn Airport and Red Roof Inn Columbia, SC Airport.
What is staying in Santee like?
Families will find kid-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and coffeehouses. In Santee, there are 127 hotels and other accommodations to choose from. Find out more about Santee.
What is there to see in Santee?
Favorite places to visit include Santee Cooper Country Club, Santee National Golf Club, and Santee State Park. A couple of additional sights to add to your agenda are Lake Marion and Santee Town Hall. Check out what more to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.