An aerial view of a coastal landscape with a dam, farmland, and dense forests.

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Check availability on Santee Family Hotels

Tonight
Oct 17 - Oct 18
Tomorrow
Oct 18 - Oct 19
Next weekend
Oct 23 - Oct 25
In two weeks
Oct 30 - Nov 1

Our top choices for Santee family-friendly hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
₩184,927
₩205,269 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A modern bathroom with a large sink, a shower with a glass door, and a towel rack.
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
  • Family fun for everyone at this Santee hotel with a seasonal pool, free breakfast, and kid-friendly extras.
₩157,748
₩175,101 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Santee-I-95
A modern lounge area with a mural, pool table, comfortable seating, and a large TV screen.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A hotel room with two beds, a desk, and a large window with a view.

3. Tru By Hilton Santee

Tru By Hilton Santee
Santee
₩134,959
₩149,803 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Santee
A hotel entrance with a sign reading "Best Western PLISS."
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.
Bathroom

4. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family vacation paradise with an outdoor pool, fitness center, and quiet, pet-friendly atmosphere for your whole family.
₩185,994
₩206,454 total
includes taxes & fees
Nov 3 - Nov 4
Best Western Plus Santee Inn
A swimming pool with a 5 ft depth marker, surrounded by lounge chairs and a building with multiple windows.
A bathroom with a dark granite countertop, a white sink, a large mirror, a toilet, and a shower with a glass door.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.

5. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
₩134,959
₩149,805 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Santee
A water park with a pool, slides, and umbrellas.
A reception desk with a wooden panel backdrop and a neon sign.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
  • Family adventure awaits at this Holiday Inn with an indoor pool, premium TV channels, and water sports equipment nearby.
₩142,765
₩158,470 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Santee by IHG
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A room with a flat-screen TV mounted on the wall, a small round table with a computer and keyboard, a chair, and a framed picture above the table.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A motel with a brick facade, a covered entrance, and a satellite dish.

7. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
₩85,392
₩94,785 total
includes taxes & fees
Nov 16 - Nov 17
Travelodge by Wyndham Santee
A modern bathroom with a sink, toilet, and shower area.
A reception area with a marble counter, a television, and a logo for 'Superstart breakfast'.
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a building with large windows.

8. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
₩85,058
₩94,415 total
includes taxes & fees
Oct 29 - Oct 30
Super 8 by Wyndham Santee/I-95
A two-story building with a flat roof and a central entrance.
A bathroom with a shower, toilet, and a towel rack.
A hotel room with a bed, bedside lamps, a nightstand, a dresser, and a bathroom visible through an open door.
A reception area with a wooden floor, a reception desk, and two red leather chairs.

9. Red Roof Inn Santee

Red Roof Inn Santee
Santee
₩84,046
₩93,291 total
includes taxes & fees
Nov 8 - Nov 9
Red Roof Inn Santee
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A hotel room with a bed, bedside tables, a chair, a desk, and a mirror.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
₩72,583
₩87,226 total
includes taxes & fees
Nov 8 - Nov 9
Quality Inn & Suites Santee I-95
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Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Family-friendly hotels with free breakfast in Santee

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A gym with treadmills, weight machines, and a wall of dumbbells.
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
₩157,748
₩175,101 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Santee-I-95
A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
₩184,927
₩205,269 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A modern lobby with a blue sofa, teal chairs, and a wooden table.
A hotel room with two beds, a desk, and a large window with a view.

Tru By Hilton Santee

Tru By Hilton Santee
Santee
₩134,959
₩149,803 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Santee
A water park with a pool, slides, and umbrellas.
A reception desk with a wooden panel backdrop and a neon sign.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
₩142,765
₩158,470 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Santee by IHG
A hotel entrance with a sign reading "Best Western PLISS."
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.

Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
₩185,994
₩206,454 total
includes taxes & fees
Nov 3 - Nov 4
Best Western Plus Santee Inn
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
₩134,959
₩149,805 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Santee
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A bathroom with a granite countertop, a sink, a mirror, and a light fixture above the mirror.
A kitchen with a countertop, cabinets, a microwave, and a sink.
A motel with a brick facade, a covered entrance, and a satellite dish.

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
₩85,392
₩94,785 total
includes taxes & fees
Nov 16 - Nov 17
Travelodge by Wyndham Santee
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.
A reception area with a marble counter, a television, and a logo for 'Superstart breakfast'.
A two-story building with a beige facade, large windows, and a central entrance.

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
₩85,058
₩94,415 total
includes taxes & fees
Oct 29 - Oct 30
Super 8 by Wyndham Santee/I-95
A two-story building with a flat roof and a central entrance.
A hotel room with a large bed, a desk, a television, and a door.
A reception area with a wooden floor, a reception desk, and two red leather chairs.
A hotel room with a television mounted on the wall displaying a sports game, a desk with a lamp, a chair, and a refrigerator.

Red Roof Inn Santee

Red Roof Inn Santee
Santee
₩84,046
₩93,291 total
includes taxes & fees
Nov 8 - Nov 9
Red Roof Inn Santee
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A hotel room with a bed, bedside tables, a chair, a desk, and a mirror.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
₩72,583
₩87,226 total
includes taxes & fees
Nov 8 - Nov 9
Quality Inn & Suites Santee I-95
View all properties

Family-friendly hotels with pools in Santee

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.
A gym with treadmills, weight machines, and a wall of dumbbells.
A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.
A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
₩157,748
₩175,101 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn Santee-I-95
A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.
A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
₩184,927
₩205,269 total
includes taxes & fees
Nov 8 - Nov 9
Fairfield Inn & Suites by Marriott Santee
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.
A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.
A modern lobby with a blue sofa, teal chairs, and a wooden table.
A hotel room with two beds, a desk, and a large window with a view.

Tru By Hilton Santee

Tru By Hilton Santee
Santee
₩134,959
₩149,803 total
includes taxes & fees
Nov 1 - Nov 2
Tru By Hilton Santee
A water park with a pool, slides, and umbrellas.
A reception desk with a wooden panel backdrop and a neon sign.
A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.
A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
₩142,765
₩158,470 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Santee by IHG
A hotel room with a large bed, a desk, a chair, a desk lamp, and a wall-mounted lamp.
A room with a black console table displaying coffee and tea options, a large window, and a sliding glass door leading to a dining area with red chairs.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A modern living room with teal and orange chairs, a grey sofa, a fireplace, and a staircase.

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
₩134,959
₩149,805 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Inn & Suites Santee
A hotel entrance with a sign reading "Best Western PLISS."
A spacious living room with a large window, a ceiling fan, and a vibrant red accent wall.
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.

Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
₩185,994
₩206,454 total
includes taxes & fees
Nov 3 - Nov 4
Best Western Plus Santee Inn
A dining area with multiple tables and chairs, a ceiling fan, and large windows.
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.
A reception area with a marble counter, a television, and a logo for 'Superstart breakfast'.
A two-story building with a beige facade, large windows, and a central entrance.

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
₩85,058
₩94,415 total
includes taxes & fees
Oct 29 - Oct 30
Super 8 by Wyndham Santee/I-95
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.
A hotel room with a bed, bedside tables, a chair, a desk, and a mirror.
A living room with a brown sofa set, a wooden coffee table, and a chandelier.
A hotel room with a flat-screen TV, a desk with a chair, a microwave, and a refrigerator.

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
₩72,583
₩87,226 total
includes taxes & fees
Nov 8 - Nov 9
Quality Inn & Suites Santee I-95
Lobby
A gym with treadmills, an elliptical, dumbbells, and a bench.
A conference room with round tables, black chairs, and white tablecloths.
Room

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
Santee
₩106,207
₩117,889 total
includes taxes & fees
Oct 18 - Oct 19
Ramada by Wyndham Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

10/10 Excellent
"It is ok"
Quantisha 2-night trip
Posted 11 hours ago
Super 8 by Wyndham, Orangeburg
Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg

10/10 Excellent
"The room was very nice and the staff was very considerate."
Linda 1-night trip
Posted 11 hours ago
Travelodge by Wyndham Orangeburg
Red Roof Inn Orangeburg

Red Roof Inn Orangeburg

10/10 Excellent
"Nice stay no complications"
JEFFREY 1-night trip
Posted 12 hours ago
Red Roof Inn Orangeburg
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Great breakfast"
Denise Cormier 1-night trip
Posted 14 hours ago
Hampton Inn Santee-I-95
Best Western Plus Santee Inn

Best Western Plus Santee Inn

10/10 Excellent
"Sería bueno que los desayunos de los Best Western fueran más variados, ya que llevo siete días hospedándome en esa cadena y los desayunos son los mismos."
Jorge 1-night trip
Posted 2 days ago
Best Western Plus Santee Inn
Holiday Inn Santee by IHG

Holiday Inn Santee by IHG

10/10 Excellent
"Staff is friendly and efficient!! Great place that we always come back to when heading on 95."
Stacey 1-night trip
Posted 3 days ago
Holiday Inn Santee by IHG
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

8/10 Good
"Great location, staff were very professional."
Levan 4-night trip
Posted 3 days ago
Spark by Hilton Orangeburg
SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

10/10 Excellent
"I like everything. And when I went to get coffee the lady cleaning in there was so nice."
Latonya 1-night trip
Posted 5 days ago
SureStay Hotel by Best Western Manning
Baymont by Wyndham Santee

Baymont by Wyndham Santee

10/10 Excellent
":)"
Robert 1-night trip
Posted 6 days ago
Baymont by Wyndham Santee

Frequently asked questions

What's Santee like for family-friendly vacations?
The welcoming destination of Santee is a great choice if you've been thinking about a vacation with the kids. The excursions, lake views, and golfing are just a few things that make this an attractive vacation spot for families. Arrange a flight into Columbia Metropolitan Airport (CAE), which is located 49 mi (78.8 km) from the city center.
What's the best place to stay for families in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another choice for your stay with the kids.
When's the best time to book a family-friendly vacation in Santee?
The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 52°F. Average annual precipitation for Santee is 55 inches.
What's there to see and do with your family in Santee?
While you and the family are vacationing in Santee, you might want to check out some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion, and Taw Caw Creek Park. Make sure you have lots of time for activities like Congaree National Park and Santee National Wildlife Refuge.

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