Find hotels near Sierra Vista Regional Medical Center, San Luis Obispo from ₩99,659

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Sierra Vista Regional Medical Center hotels

Junior Suite, City View | Terrace/patio
Petit Soleil

Petit Soleil

Petit Soleil
3.5 star property
MoJo, 1.3 km from Sierra Vista Regional Medical Center
9.8 out of 10, Exceptional, (276)
"Clean and comfy rooms."
United Kingdom
Michelle
The price is ₩193,644
₩219,787 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Petit Soleil
Free daily buffet breakfast
Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo
3.0 star property
1.3 km from Sierra Vista Regional Medical Center
9.4 out of 10, Exceptional, (1306)
"We felt relaxed and comfortable here"
United States
lin
The price is ₩174,150
₩234,101 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Suites Downtown San Luis Obispo
Morro Suite | Living area | 55-inch flat-screen TV with cable channels, TV
Hotel San Luis Obispo

Hotel San Luis Obispo

Hotel San Luis Obispo
4.5 star property
Downtown San Luis Obispo, 1.3 km from Sierra Vista Regional Medical Center
9.4 out of 10, Exceptional, (559)
"Great space, friendly staff and good restaurants - we thoroughly enjoyed ourselves. "
United States
michelle
The price is ₩497,411
₩564,573 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hotel San Luis Obispo
Egyptian cotton sheets, premium bedding, down comforters, minibar
San Luis Creek Lodge

San Luis Creek Lodge

San Luis Creek Lodge
3.0 star property
1.4 km from Sierra Vista Regional Medical Center
9.4 out of 10, Exceptional, (1001)
"Beautiful cozy room, great staff, good location, clean and modern. "
United States
Rasa
The price is ₩200,720
₩254,481 total
includes taxes & fees
Jan 4 - Jan 5, 2026
San Luis Creek Lodge
Outdoor pool, sun loungers
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
3.0 star property
1.4 km from Sierra Vista Regional Medical Center
9.0 out of 10, Wonderful, (1812)
"Clean rooms and very nice staff"
United States
Ana
The price is ₩167,262
₩190,169 total
includes taxes & fees
Jan 19 - Jan 20, 2026
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Meeting facility
The Wayfarer San Luis Obispo, Tapestry Collection by Hilton

The Wayfarer San Luis Obispo, Tapestry Collection by Hilton

The Wayfarer San Luis Obispo, Tapestry Collection by Hilton
3.5 star property
1.3 km from Sierra Vista Regional Medical Center
9.0 out of 10, Wonderful, (1001)
"Great location and friendly staff."
United States
Lisa
The price is ₩170,139
₩200,257 total
includes taxes & fees
Dec 30 - Dec 31
The Wayfarer San Luis Obispo, Tapestry Collection by Hilton
Aerial view
Apple Farm

Apple Farm

Apple Farm
3.5 star property
1.5 km from Sierra Vista Regional Medical Center
9.0 out of 10, Wonderful, (1574)
"Beautiful hotel and a wonderful staff."
United States
Nadia
Apple Farm
Terrace/patio
La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection
2.5 star property
1.4 km from Sierra Vista Regional Medical Center
8.8 out of 10, Excellent, (1085)
"Room was clean and spacious Staff was very helpful Morning breakfast was awesome (thank you Vicky) Close to freeway access Very reasonable cost wise "
United States
Thomas
The price is ₩154,656
₩175,534 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Cuesta Inn, BW Signature Collection
Exterior
Granada Hotel & Bistro

Granada Hotel & Bistro

Granada Hotel & Bistro
4.0 star property
Downtown San Luis Obispo, 1.5 km from Sierra Vista Regional Medical Center
9.2 out of 10, Wonderful, (808)
"Enjoyed the hotel."
United States
Donovan
The price is ₩279,661
₩317,961 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Granada Hotel & Bistro
Property entrance
Garden Street Inn, A Kirkwood Collection Hotel

Garden Street Inn, A Kirkwood Collection Hotel

Garden Street Inn, A Kirkwood Collection Hotel
4.0 star property
Downtown San Luis Obispo, 1.7 km from Sierra Vista Regional Medical Center
9.2 out of 10, Wonderful, (727)
"Spotless room, very courteuos staff."
United States
Jenny
The price is ₩377,321
₩428,259 total
includes taxes & fees
Dec 29 - Dec 30
Garden Street Inn, A Kirkwood Collection Hotel
Property grounds
Peach Tree Inn

Peach Tree Inn

Peach Tree Inn
2.0 star property
1.4 km from Sierra Vista Regional Medical Center
8.8 out of 10, Excellent, (1000)
"Very cordial staff, great rooms and location."
United States
Chad
The price is ₩128,519
₩155,710 total
includes taxes & fees
Dec 28 - Dec 29
Peach Tree Inn
Sundeck
HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
4.0 star property
Downtown San Luis Obispo, 1.6 km from Sierra Vista Regional Medical Center
9.2 out of 10, Wonderful, (470)
"Excellent! So accommodating and eager to offer top notch service. Early check in, great referrals into town and spotless!"
United States
Melissa
The price is ₩329,239
₩423,585 total
includes taxes & fees
Jan 4 - Jan 5, 2026
HOTEL CERRO, Autograph Collection
Breakfast area
San Luis Inn And Suites

San Luis Inn And Suites

San Luis Inn And Suites
2.0 star property
Foothill, 0.7 km from Sierra Vista Regional Medical Center
7.0 out of 10, Good, (331)
"Love going to the hotel here the lady at the desk is always amazing "
United States
arturo
The price is ₩69,972
₩120,394 total
includes taxes & fees
Dec 28 - Dec 29
San Luis Inn And Suites
Standard Room, 1 Queen Bed | Desk, iron/ironing board, free WiFi, bed sheets
Sunbeam Motel

Sunbeam Motel

Sunbeam Motel
2.0 star property
1.3 km from Sierra Vista Regional Medical Center
8.2 out of 10, Very Good, (757)
"Great place to stay and walking distance to downtown SLO."
United States
steve
The price is ₩114,078
₩129,486 total
includes taxes & fees
Dec 28 - Dec 29
Sunbeam Motel
Free daily on-the-go breakfast
University Inn

University Inn

University Inn
2.0 star property
1.3 km from Sierra Vista Regional Medical Center
8.0 out of 10, Very Good, (1000)
"The room is very good for a motel. "
United States
Maria
University Inn
Lobby
Sands Inn & Suites

Sands Inn & Suites

Sands Inn & Suites
2.5 star property
1.4 km from Sierra Vista Regional Medical Center
8.0 out of 10, Very Good, (453)
"Great time "
United States
Marissa
Sands Inn & Suites
Front of property
Hotel Buena Vista

Hotel Buena Vista

Hotel Buena Vista
2.5 star property
1.4 km from Sierra Vista Regional Medical Center
8.2 out of 10, Very Good, (884)
"Room was spacious. I’ve stayed here before would recommend affordable and good service. I’ll be booking again. "
United States
Diane
Hotel Buena Vista
Soundproofing, iron/ironing board, free WiFi, bed sheets
Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo

Avenue Inn Downtown San Luis Obispo
2.5 star property
Lower Higuera, 2 km from Sierra Vista Regional Medical Center
9.0 out of 10, Wonderful, (1142)
"Good room, nice staff."
United States
annamalai
The price is ₩114,078
₩129,478 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Avenue Inn Downtown San Luis Obispo
Lobby sitting area
Inn at San Luis Obispo

Inn at San Luis Obispo

Inn at San Luis Obispo
2.5 star property
1.4 km from Sierra Vista Regional Medical Center
7.6 out of 10, Good, (1001)
"The Inn was a terrific location for a visit to Cal Poly. The hotel was quiet and clean and a good value. We would definitely stay here again."
United States
Craig
The price is ₩87,805
₩99,659 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Inn at San Luis Obispo
Property entrance
Mission Inn San Luis Obispo

Mission Inn San Luis Obispo

Mission Inn San Luis Obispo
2.0 star property
1.5 km from Sierra Vista Regional Medical Center
7.8 out of 10, Good, (899)
"room was very clean and staff very friendly. "
United States
Sonia
The price is ₩91,889
₩121,083 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Mission Inn San Luis Obispo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sierra Vista Regional Medical Center Hotel Reviews

San Luis Creek Lodge

San Luis Creek Lodge

10/10 Excellent
"Excellent"
Tracy 1-night trip
Posted 4 days ago
San Luis Creek Lodge

Hotels near other Sierra Vista Regional Medical Center attractions

SanLuisObispo_SantaRosaPark_553248635118923043_04

Santa Rosa Park

After visiting Santa Rosa Park, make a plan to see the other sights and activities in San Luis Obispo. Amble around this family-friendly area's beautiful beaches and enjoy its top-notch restaurants.
See properties
SanLuisObispo_AlexGSpanosStadium_6089189_02

Alex G. Spanos Stadium

Catch an event at Alex G. Spanos Stadium, and enjoy other activities in San Luis Obispo such as biking. Discover the beautiful sunsets and top-notch restaurants in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Sierra Vista Regional Medical Center?
Sierra Vista Regional Medical Center is located in a family-friendly area of San Luis Obispo known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, check out the 53 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Sierra Vista Regional Medical Center?
Quality Suites Downtown San Luis Obispo is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. It's located just a short 0.8 mi (1.3 km) from Sierra Vista Regional Medical Center. Other good choices within a short distance include La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown and Apple Farm.
How many hotels will I be able to find close to Sierra Vista Regional Medical Center?
Expedia has 53 hotels and other accommodations within a mile from Sierra Vista Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Sierra Vista Regional Medical Center, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals available near Sierra Vista Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Sierra Vista Regional Medical Center?
For additional details about updating your stay near Sierra Vista Regional Medical Center or cancelling it, click here.
What can I see and do near Sierra Vista Regional Medical Center?
You'll want to browse the collections at History Center of San Luis Obispo County, San Luis Obispo Museum of Art, and San Luis Obispo Railroad Museum. Fremont Theater, Ah Louis Store, and Dallidet Adobe and Gardens are notable landmarks to explore if you're in the area. You can check out the local talent at Performing Arts Center, San Luis Obispo Little Theatre, and Sunset Drive-In Theatre.