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Find Boutique Hotels in South San Francisco, CA

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Check availability on South San Francisco Boutique Hotels

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for South San Francisco boutique hotels

Game room
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
Fisherman's Wharf
8.6 out of 10, Excellent, (2341)
"Great location"
United States
Deborah
The price is ₩178,938
₩261,083 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Zephyr San Francisco
Indoor pool
Berkeley City Club

Berkeley City Club

Berkeley City Club
2.5 star property
Telegraph District
8.8 out of 10, Excellent, (697)
"Wonderful, beautiful, old world hotel, right in the heart of bustling Berkeley. "
United States
Peter
Berkeley City Club
Exterior
Argonaut Hotel

Argonaut Hotel

Argonaut Hotel
4.5 star property
Fisherman's Wharf
9.4 out of 10, Exceptional, (1216)
"Absolutely amazing hotel!"
United States
Alicia
The price is ₩229,768
₩331,002 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Argonaut Hotel
Suite, Multiple Beds (The Two Bedroom) | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar
Palihotel San Francisco

Palihotel San Francisco

Palihotel San Francisco
3.5 star property
Union Square
8.4 out of 10, Very Good, (632)
"Great vibe here and the rooms and so cute . Excellent bar and bar staff . "
United States
Lana
The price is ₩150,116
₩212,421 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Palihotel San Francisco
Front of property - evening/night
Hotel Abri - Union Square

Hotel Abri - Union Square

Hotel Abri - Union Square
3.5 star property
Union Square
8.6 out of 10, Excellent, (1002)
"Very nice hotel"
United States
Mariam
The price is ₩133,901
₩215,261 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Abri - Union Square
Lobby sitting area
The Marker Union Square San Francisco

The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
Union Square
9.0 out of 10, Wonderful, (1131)
"The staff was so fabulous, the hotel is gorgeous, and we are already having the best time!"
United States
Faith
The price is ₩199,612
₩234,933 total
includes taxes & fees
Jan 3 - Jan 4, 2026
The Marker Union Square San Francisco
Meeting facility
The Barnes San Francisco, Tapestry Collection by Hilton

The Barnes San Francisco, Tapestry Collection by Hilton

The Barnes San Francisco, Tapestry Collection by Hilton
4.0 star property
Union Square
8.2 out of 10, Very Good, (779)
"Wonderful Stay, Room was Clean. Close to Union Square. Would Stay Here again. "
United States
Raquel
The price is ₩200,391
₩235,850 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Barnes San Francisco, Tapestry Collection by Hilton
Lobby
The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott

The Clancy, Autograph Collection by Marriott
4.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1001)
"Very professional staff! Central located walking distance to everything!"
United States
Edmundo
The price is ₩235,440
₩336,331 total
includes taxes & fees
Jan 24 - Jan 25, 2026
The Clancy, Autograph Collection by Marriott
Exterior
Hotel Emblem San Francisco

Hotel Emblem San Francisco

Hotel Emblem San Francisco
4.0 star property
Union Square
9.4 out of 10, Exceptional, (1003)
"We enjoyed our stay, close to cable cars shopping dining bars "
United States
HALEY
The price is ₩160,410
₩246,010 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hotel Emblem San Francisco
Room (Private Apartment) | Egyptian cotton sheets, premium bedding, minibar, in-room safe
The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco

The Clift Royal Sonesta San Francisco
4.0 star property
Union Square
9.2 out of 10, Wonderful, (1370)
"clean, well appointed room in a good location."
United States
Susanna
The price is ₩193,326
₩283,761 total
includes taxes & fees
Jan 16 - Jan 17, 2026
The Clift Royal Sonesta San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South San Francisco Hotel Reviews

Fairmont San Francisco

Fairmont San Francisco

10/10 Excellent
"It is a beautiful place to visit around the holidays, for he was a bit busy but still enjoyed our stay and the galleries inside, the Tonga Room, customer service was excellent and very kind From the lady checking us in to the valet , everyone was very helpful and cordial They make you feel like a VIP "
Cathya 1-night trip
Posted 20 hours ago
Fairmont San Francisco

Frequently asked questions

What's there to see and do in South San Francisco?
The shopping, restaurants, and cafes are just some of the things to enjoy while you're in the area. While you're out and about in South San Francisco, popular attractions like San Francisco Bay, Oracle Park, and Pier 39 are worth a visit. For even more to see and do, make a stop at Santa Cruz Mountains, See's Candies, and San Bruno Point Park.
What kind of weather should I plan for when I travel to South San Francisco?
Having a good idea of the weather in South San Francisco is important when you plan your trip. The hottest months are usually September and August with an average temp of 62°F, while the coldest months are February and January with an average of 53°F. Average annual precipitation for South San Francisco is 23 inches.
What's the best way to get to my boutique hotel in South San Francisco?
You have a few options for traveling to and around South San Francisco. The closest major airport is San Francisco Intl. Airport (SFO), which is located 2.9 mi (4.6 km) from the heart of the city, but Oakland Intl. Airport (OAK) may also be an option. Make your way to South San Francisco Metro Station for metro transit. To venture out into the surrounding area, hop on a train at South San Francisco Station.