Top 10 Hotels in Southern Illinois, IL - Competitive Prices

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Our top choices for Southern Illinois hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.

A spacious lobby with a reception desk, seating area, and glass doors leading outside.

A hotel room with two beds, a desk with a flat-screen TV, a chair, and a lamp.

An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

1. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

₩150,288

₩169,497 total

includes taxes & fees

Oct 11 - Oct 12

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.

A hotel room with two beds, a large window, and a wall-mounted lamp.

A modern kitchen with a wooden cabinet, coffee maker, and storage shelves.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a window providing natural light.

2. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

John

₩159,780

₩180,032 total

includes taxes & fees

Oct 9 - Oct 10

A hotel lobby with a reception desk, seating area, and a large screen TV.

A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.

A Comfort Suites hotel with a spacious parking lot and a modern brick facade.

A brick building with a patio area featuring wicker furniture and a table.

3. Comfort Suites Mount Vernon

Mount Vernon

Lori

₩165,629

₩186,523 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.

A modern living area with a sectional sofa, a fireplace, and a flat-screen TV.

A treats section with a variety of snacks and beverages, including a refrigerated display and shelves stocked with items like Welch's and Bonde.

A hotel lobby with a large indoor pool, a reception desk, and a seating area.

4. Hampton Inn & Suites Effingham

Effingham

Karen

₩177,128

₩196,577 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.

A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a television, and a framed artwork on the wall.

A hotel room with a desk, two monitors, a keyboard, and a mouse.

A Best Western hotel with a modern facade, a parking lot, and a clear sky.

5. Best Western Delta Inn

Effingham

Susan

₩117,379

₩131,441 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.

A parking lot with a Super 8 sign, a white car, and a truck.

A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.

6. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Devin

₩98,847

₩112,409 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.

A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.

An outdoor patio area with tables and chairs, large windows, and red umbrellas.

7. DoubleTree by Hilton Mt. Vernon

Mount Vernon

Kenneth

₩173,158

₩194,878 total

includes taxes & fees

Oct 8 - Oct 9

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

An indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls. There are lounge chairs and a small seating area with tables.

A spacious lobby with a large seating area, a reception desk, and a television.

A modern kitchen with a checkered tile backsplash, wooden flooring, and stainless steel appliances.

8. Best Western Plus Centralia Hotel & Suites

Centralia

Jeremy

₩188,216

₩210,761 total

includes taxes & fees

Oct 27 - Oct 28

A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

A hotel room with a large bed, a desk with a chair, a flat-screen TV, a bathtub, and framed pictures on the wall.

An indoor swimming pool with lounge chairs and a clear view of the pool area.

A modern kitchen area with a counter, various appliances, and food display items.

9. La Quinta Inn & Suites by Wyndham Effingham

Effingham

Alexis

₩150,133

₩168,118 total

includes taxes & fees

Oct 4 - Oct 5

A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

A hotel room with a large bathtub, a desk with a chair, and a bed.

A modern dining area with round tables and chairs, a green booth seating area, and artwork on the walls.

A Fairfield Inn & Suites by Marriott hotel with a parking lot and a clear sky.

10. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Mount Vernon

Susan

₩148,244

₩167,230 total

includes taxes & fees

Oct 10 - Oct 11

A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.

An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.

An indoor swimming pool with clear water, tiled walls, and a ceiling with square vents.

A spacious lobby with a high ceiling, a central seating area with multiple chairs, a reception desk, and a kitchen area in the background.

11. Drury Inn & Suites Marion

Marion

kevin

₩126,332

₩151,573 total

includes taxes & fees

Oct 18 - Oct 19

A modern breakfast bar with a coffee machine, cereal, and fruit display.

A Holiday Inn Express hotel with a brick facade, large windows, and a covered entrance.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A coffee station with multiple coffee dispensers, a hot water station, and a variety of coffee products on display.

12. Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Marion

Jennifer

₩148,082

₩177,668 total

includes taxes & fees

Oct 4 - Oct 5

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and landscaped gardens.

A modern kitchen with a central island, bar stools, and various appliances.

A hotel room with a bed, bedside table, lamp, desk, chair, and a television.

A spacious lobby with a reception desk, seating area, and a kitchen in the background.

13. Comfort Inn & Suites Marion I-57

Marion

Daniel

₩147,323

₩176,757 total

includes taxes & fees

Oct 25 - Oct 26

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.

A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.

A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

A casino interior with slot machines, a large chandelier, and a carpeted floor.

14. Walker's Bluff Casino Resort

Carterville

Kyle

₩231,478

₩256,894 total

includes taxes & fees

Sep 30 - Oct 1

A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

A hallway with vending machines and a carpeted floor.

A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.

15. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

MARK

₩109,666

₩121,708 total

includes taxes & fees

Oct 5 - Oct 6

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

A modern kitchen with a coffee station, fruit display, and a waffle advertisement.

A snack and treat section with shelves stocked with various snacks, a 'Welcome to our store' sign, and a 'Treats' sign.

A modern hotel lobby with a seating area, a reception desk, and a 'Treats' sign in the background.

16. Hampton Inn O'Fallon

O'Fallon

Edmond

₩149,896

₩173,848 total

includes taxes & fees

Oct 11 - Oct 12

A small, clean room with a microwave, a vending machine, and a table with chairs.

A self-service laundry station with multiple washing machines, a price tag of $1.50, and a sign indicating guest services at the lobby.

A hotel room with two beds, a small kitchenette, and a dining area.

A bathroom with a shower, a bathtub, and a toilet.

17. Rodeway Inn Mount Vernon, IL

Mount Vernon

Emil

₩92,077

₩104,896 total

includes taxes & fees

Oct 5 - Oct 6

A banquet hall with tables set for a formal event, draped with white fabric and string lights, and a chandelier above.

A Holiday Inn lobby with a reception desk, two armchairs, and a decorative ceiling light.

A spacious restaurant with high ceilings, large windows, and a variety of seating arrangements including tables and chairs.

18. Holiday Inn Effingham by IHG

Effingham

Penny

₩154,875

₩173,428 total

includes taxes & fees

Oct 26 - Oct 27

A Country Inn & Suites building with a covered entrance and a sign.

A restaurant with wooden tables and chairs, a coffee bar with various appliances, and a TV mounted on the wall.

A building with a green roof, white columns, and a glass entrance.

An indoor swimming pool with clear lane markings, a lifeguard chair, and a no diving sign.

19. Country Inn & Suites by Radisson, Effingham, IL

Effingham

Larry

₩116,781

₩129,604 total

includes taxes & fees

Oct 25 - Oct 26

A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

A hotel room with two beds, a nightstand, a lamp, and a framed picture on the wall.

A laundry area with two washers and dryers, a coin-operated machine, and a sign indicating the coin slot locks out when empty.

A reception area with a desk, chairs, a red carpet, and a television mounted on the wall.

20. Quality Inn Mount Vernon, IL

Mount Vernon

Matthew

₩102,368

₩116,317 total

includes taxes & fees

Oct 11 - Oct 12

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Vacation Rentals in Southern Illinois

Cottage

A covered porch with blue plastic chairs, a ceiling fan, and large windows offering a view of the outdoors.

A kitchen with wooden cabinets, a checkered backsplash, a sink, and a dining area with chairs and a table.

A single-story house with a stone foundation and a gabled roof, surrounded by a small lawn and a wooden fence.

A bedroom with a bed, a nightstand, a mirror, a ceiling fan, and a door leading to a bathroom.

Harrisburg Home w/ Private Yard + Screened Porch!

Harrisburg

"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."

Cottage

A modern kitchen with dark cabinets, a round dining table, and a tufted bench.

A bedroom with a bed, a chair, a window, and two framed pictures on the wall.

A modern living room with a flat-screen TV, wooden entertainment unit, leather sofa, and a dining table.

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Robinson

Cottage

A living room with a fireplace, leather sofas, and a clock on the wall.

A modern kitchen with wooden cabinets, a white refrigerator, and a microwave. There is a dining area with a table and chairs, and a living room with a couch and a fireplace.

A spacious living room with leather sofas, a dining table, and a ceiling fan.

A room with a wooden wall, a window with a view of a deck and outdoor area, and a potted plant with flowers on a table.

Illinois Vacation Rental Home: Pets Welcome

Palestine

Cottage

A long, narrow hallway with wooden floors and large windows.

A modern kitchen with a stainless steel refrigerator, oven, and dishwasher. There is a wooden dining table and a brick accent wall.

A covered porch with wooden flooring, a bench, and large windows.

A single-story house with a front porch, a central entrance, and a small staircase leading to the door.

Cozy Anna Home Near Southern Illinois Attractions!

Anna

"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."

Cottage

A wooden deck with a ceiling fan, outdoor furniture, and a view of a garden.

A wooden cabin with a porch, surrounded by a grassy yard and trees.

A wooden cabin with a porch, surrounded by trees and grass.

A modern kitchen with wooden cabinets, stainless steel appliances, and a central island with bar stools.

Beautiful Makanda Cabin in Shawnee National Forest

Makanda

"It was very peaceful and relaxing. "

See all vacation rentals

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Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

See properties

World Wide Technology Raceway

9.0/10 (2 reviews)

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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O'Fallon Family Sports Park

8.6/10 (137 reviews)

This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.

See properties

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"Another excellent Drury property. This one has an integrated A/C rather than the typical exterior wall mounted unit. Because of that the air handler is very quiet. I'm sure some like this but I did miss the fan noise from the wall mounted unit"

Comfort Suites Mount Vernon

8/10 Good

"Finally a room with a walk in shower and grab bars by toilet"

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Fabulous that I arrived & had Happy Hour Meal with Drinks & a great breakfast! Thx! Dennis D."

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent

"GREAT PLACE! Comfortable beds, great pillow, excellent breakfast with extended hours compared to other places I've stayed. Would definitely stay again."

Quality Inn & Suites Metropolis I-24

8/10 Good

"Serves breakfast. But only thing they had was waffles, toast, apples and yogurt. Room was clean, bathroom looked like had mold on walls. Bathtub looked nasty. Didnt even use it. Cause checked in late and left early."

Ramada by Wyndham Effingham

10/10 Excellent

"It is a modest hotel with helpful staff, easily accessible handicapped parking, and surprisingly good scrambled eggs :)"

Comfort Inn Edwardsville - St. Louis

10/10 Excellent

"Property was well maintained. The room was clean and the bed was comfortable. The shower looked a little worn in some spots but it was fine overall. Room was cool and you could control the temperature. The breakfast was great and a nice touch every morning. Food was fresh and hot. Staff was friendly. We came for family weekend and we would stay again."

Walker's Bluff Casino Resort

10/10 Excellent

"The staff were very kind and helpful! The security guard even noticed my trunk was opened and closed it for me. I’ve stayed twice and both times the hotel and room was very clean and staff were friendly and welcoming. My only two complaints would be that the music in the lobby is loud and annoying and that the breakfast isn’t worth the price. But those things won’t keep from staying again when I’m in the area. I think the hotel clerk was Miranda in the evening and she was above and beyond friendly!"

Radisson Hotel Fairview Heights - St. Louis

8/10 Good

"Our stay at the Radisson was good overall and the prices are good . The location was convenient to restaurants and shopping .The first room had a wet carpet smell and the front desk was notified and immediately moved us to another room . The bed was comfortable, the bar inside was nice and reasonably priced. The property was clean and everyone was friendly . My only complaint would be our towels had stains on them and the room had minor spots and stains in certain areas but overall the stay was nice and we would definitely stay again ."

Hotels in Southern Illinois with star-rating

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Find hotels in Southern Illinois, IL

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Southern Illinois

Check prices for these dates

Filter by

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Our top choices for Southern Illinois hotels

1. Drury Plaza Hotel Mt. Vernon

2. Holiday Inn Express & Suites Mount Vernon by IHG

3. Comfort Suites Mount Vernon

4. Hampton Inn & Suites Effingham

5. Best Western Delta Inn

6. Super 8 by Wyndham Mt. Vernon IL

7. DoubleTree by Hilton Mt. Vernon

8. Best Western Plus Centralia Hotel & Suites

9. La Quinta Inn & Suites by Wyndham Effingham

10. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

11. Drury Inn & Suites Marion

12. Holiday Inn Express Hotel & Suites Marion Northeast by IHG

13. Comfort Inn & Suites Marion I-57

14. Walker's Bluff Casino Resort

15. SureStay Hotel by Best Western Whittington Rend Lake

16. Hampton Inn O'Fallon

17. Rodeway Inn Mount Vernon, IL

18. Holiday Inn Effingham by IHG

19. Country Inn & Suites by Radisson, Effingham, IL

20. Quality Inn Mount Vernon, IL

Vacation Rentals in Southern Illinois

Harrisburg Home w/ Private Yard + Screened Porch!

Peaceful Robinson Home w/ Yard, Near Golf Courses!

Illinois Vacation Rental Home: Pets Welcome

Cozy Anna Home Near Southern Illinois Attractions!

Beautiful Makanda Cabin in Shawnee National Forest

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

World Wide Technology Raceway

O'Fallon Family Sports Park

Learn more about Southern Illinois

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Comfort Suites Mount Vernon

Drury Inn & Suites St. Louis O'Fallon, IL

Country Inn & Suites by Radisson, Effingham, IL

Quality Inn & Suites Metropolis I-24

Ramada by Wyndham Effingham

Comfort Inn Edwardsville - St. Louis

Walker's Bluff Casino Resort

Radisson Hotel Fairview Heights - St. Louis

Hotels in Southern Illinois with star-rating

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