La Quinta Inn & Suites Hotels: Book La Quinta Inn & Suites Hotel Rooms & Suites in Southern Illinois, Illinois

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"We really enjoyed our stay at the Drury Inn in O'Fallon. Our boys were able to swim each night. We enjoyed the breakfast (great variety and super helpful staff!) and also the dinner at happy hour. At one point, we couldn't get our key card to work and one of the ladies at the front desk took the time to help sort out the key issue by coming with us to the door to see why it wasn't working."