Our top choices for Southern Indiana hotels

Derby Hotel & Suites

Clarksville

charles N

₩101,318 total

includes taxes & fees

Feb 16 - Feb 17

Comfort Inn Jasper South

Jasper

Enjoy Jasper's top attractions while staying at a hotel with indoor swimming.

Rita

₩136,077 total

includes taxes & fees

Feb 21 - Feb 22

Deluxe Room | Living area | 55-inch Smart TV with digital channels, TV, Netflix

The Chandler Hotel

Madison

Welcoming Madison hotel with free perks and easy access to local wineries.

julie

₩222,659 total

includes taxes & fees

Feb 16 - Feb 17

Hampton Inn Evansville/Airport

Evansville

Convenient airport hotel with free shuttle and indoor pool for relaxed travelers.

Karianne

₩155,213 total

includes taxes & fees

Feb 21 - Feb 22

Comfort Inn Madison near Clifty Falls

Madison

Relaxing comfort near Clifty Falls with indoor pool and sauna for year-round fun.

Katherine

₩153,819 total

includes taxes & fees

Feb 22 - Feb 23

SpringHill Suites by Marriott Newburgh Evansville

Newburgh

Unwind in Newburgh with free breakfast and indoor pool near Ohio River Valley.

Josie

₩202,135 total

includes taxes & fees

Feb 20 - Feb 21

Jasper Inn

Jasper

Tranquil Jasper hotel with indoor pool and fitness amenities near local sights.

Dawn

₩113,195 total

includes taxes & fees

Feb 16 - Feb 17

Desk, iron/ironing board, free cribs/infant beds, rollaway beds

Hillside Inn

Madison

Alta

₩147,948 total

includes taxes & fees

Feb 16 - Feb 17

Fairfield Inn & Suites Madison Historic Eagle Cotton Mill

Madison

A former cotton mill transformed into a riverside retreat with free breakfast and Wi-Fi.

shannon

₩210,869 total

includes taxes & fees

Feb 22 - Feb 23

27-inch Smart TV with satellite channels

The Duke Hotel

Downtown Louisville

₩202,777 total

includes taxes & fees

Feb 17 - Feb 18

Belterra Casino Resort

Florence

Enjoy golf, gaming, and riverside views at this upscale resort on the Ohio River.

Julie L

₩236,396 total

includes taxes & fees

Feb 18 - Feb 19

3 restaurants, breakfast, lunch, dinner served; American cuisine

Caesars Southern Indiana - A Caesars Rewards Destination

Elizabeth

Ismael

₩203,566 total

includes taxes & fees

Feb 16 - Feb 17

Comfort Inn Ferdinand

Ferdinand

Enjoy convenience and comfort in a friendly hotel with indoor pool in Ferdinand.

Frank

₩129,528 total

includes taxes & fees

Feb 21 - Feb 22

Best Western Plus French Lick

French Lick

Experience French Lick with easy access to local attractions and daily breakfast.

Kylee

₩158,982 total

includes taxes & fees

Feb 22 - Feb 23

Bally’s Evansville Casino & Hotel

Downtown Evansville

Enjoy a casino-adjacent stay with 3 dining options and lively nightlife entertainment.

JOSH

₩144,689 total

includes taxes & fees

Mar 15 - Mar 16

Suite, 2 Double Beds, Pets Not Allowed | Private kitchenette | Fridge, microwave, coffee/tea maker

Knights Inn and Suites Salem

Salem

Salem hotel offering free breakfast and peaceful atmosphere for great sleep.

Jennifer

₩111,405 total

includes taxes & fees

Feb 16 - Feb 17

Ramada by Wyndham Sellersburg/Louisville North

Sellersburg

Experience comfort just 15 minutes from Kentucky Convention Center and KFC Yum Center.

Karen

₩124,827 total

includes taxes & fees

Mar 1 - Mar 2

Hilton Garden Inn Jeffersonville Louisville North

Jeffersonville

Modern Louisville hotel close to downtown attractions and convention center.

STEVEN

₩162,059 total

includes taxes & fees

Feb 20 - Feb 21

Radisson Hotel Louisville North

Clarksville

Relaxing riverside retreat with both indoor and outdoor pools just minutes from Louisville.

Beant

₩96,410 total

includes taxes & fees

Mar 18 - Mar 19

Standard Room, 2 Queen Beds, Non Smoking | Hypo-allergenic bedding, in-room safe, laptop workspace, blackout drapes

Clarion Pointe Jasper

Jasper

Enjoy a complete family getaway with free kids' club and outdoor pool in Jasper.

James

₩115,460 total

includes taxes & fees

Feb 22 - Feb 23

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Vacation Rentals in Southern Indiana

Condo

The Villas at French Lick Springs

Downtown French Lick

"Always a great, relaxing time!"

Apartment

Historic New Albany Apartment ~ 6 Mi to Louisville

New Albany

"Amazing historic building in a district full of historic buildings and walkable attractions."

Aparthotel

CozySuites at Nulu

Downtown Louisville

"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "

Aparthotel

The Reserve on Main

Downtown Louisville

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

Cottage

'the Bovard Lodge' Rustic Cabin Near Ohio River!

Florence

Cottage

Modern Eckerty Home w/ Deck on Patoka Lake!

Eckerty

Cottage

Orleans Retreat w/ Private Hot Tub & Fireplace!

Orleans

"Our stay was great! Loved everything about it!"

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Stay near popular Central United States attractions

Panorama Ohio River waterway riverboats and bridges leading to heart of downtown Louisville KY

KFC Yum Center

4.3/5 (799 reviews)

This waterfront arena hosts Louisville's premier sporting events and world-class concerts with 22,000 seats. Arrive early to explore downtown's culinary scene before experiencing the vibrant atmosphere inside.

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Louisville Slugger Museum

4.5/5 (1,200 reviews)

Step inside the world's only Louisville Slugger factory where baseball history comes alive. Watch craftsmen transform raw wood into iconic bats, then hold the same models used by legends like Babe Ruth and Derek Jeter.

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Learn more about Southern Indiana

Live music, casinos, and top sights like KFC Yum Center—discover it all in Southern Indiana.

See all hotels in Southern Indiana

Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people

Top Southern Indiana Hotel Reviews

Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent

"Yes"

Drury Inn & Suites Evansville East

10/10 Excellent

"I always love these hotels. They are one of the only things left in America that is true value for your money. Always super friendly and helpful staff, very clean, and nice meals. My one complaint was that this was a bit of an older building so you could hear a fair bit of outside and inside noise but I would still stay here again. "

Radisson Hotel Louisville North

10/10 Excellent

"Everything in the room worked everything was clean and spotless the staff was very sweet especially Miss Jenny thank you Ms Jenny the pool was clean although it was a little cold but that was just because the ceiling fan was on and it's kind of an open pool but we enjoyed every moment. We will be back"