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Our top choices for Southern Minnesota hotels

An indoor swimming pool with a curved design, surrounded by palm trees and a white pool ladder.

1. Treasure Island Resort & Casino

Welch

Jacob

₩147,451 total

includes taxes & fees

Nov 16 - Nov 17

A long dining table with chairs, a fireplace, a flat-screen TV mounted on the wall, and a painting on the wall.

2. AmericInn by Wyndham Mankato Event Center

Mankato

Brian

₩117,084 total

includes taxes & fees

Nov 15 - Nov 16

A modern dining area with high tables, chairs, and pendant lighting.

3. Hampton Inn & Suites Rochester-North

Rochester

Mark

₩150,069 total

includes taxes & fees

Nov 28 - Nov 29

An outdoor patio area with tables and chairs, stone pillars, and a building labeled "Courtyard."

4. Courtyard Mankato Marriott

Mankato

John

₩145,302 total

includes taxes & fees

Nov 22 - Nov 23

A Comfort Inn & Suites building with a covered entrance, numbered 2000, and a parking lot with cars.

5. Comfort Inn & Suites North Mankato

Mankato

Jeffrey

₩131,703 total

includes taxes & fees

Dec 6 - Dec 7

A spacious indoor pool area with multiple levels, a hot tub, and a seating area with tables and chairs.

6. Best Western Plus New Ulm

New Ulm

Betsy

₩175,935 total

includes taxes & fees

Dec 1 - Dec 2

A hotel lobby with a reception desk, seating area with sofas and chairs, framed artwork on the walls, and large windows providing natural light.

7. Holiday Inn Express & Suites Worthington by IHG

Worthington

Kirsten

₩149,336 total

includes taxes & fees

Dec 13 - Dec 14

A modern American Inn by Wyndham with a parking lot and a clear sky.

8. AmericInn By Wyndham Mountain Lake Mn

Mountain Lake

Misty

₩185,572 total

includes taxes & fees

Dec 3 - Dec 4

A bar area with a long counter, multiple stools, and framed pictures on the wall.

9. Country Inn & Suites by Radisson, Mankato Hotel and Conference Center, MN

Mankato

Bridget

₩145,418 total

includes taxes & fees

Dec 13 - Dec 14

A La Quinta Inn & Suites hotel with a well-lit entrance, a parking area, and a clear view of the building's facade.

10. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Rochester

Joseph

₩109,616 total

includes taxes & fees

Nov 22 - Nov 23

A multi-story hotel with a prominent "American" sign, a parking lot with several cars, and a landscaped entrance area.

11. AmericInn by Wyndham Winona

Winona

Jonathan

₩196,119 total

includes taxes & fees

Nov 18 - Nov 19

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

12. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

Robert Blaise

₩170,719 total

includes taxes & fees

Nov 27 - Nov 28

A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

13. Hampton Inn Rochester-South

Rochester

Susan

₩148,767 total

includes taxes & fees

Dec 12 - Dec 13

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

14. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

Ashley

₩193,039 total

includes taxes & fees

Nov 27 - Nov 28

A hotel with a central entrance, stone pillars, and a sign above the entrance.

15. Cobblestone Hotel & Suites - Austin

Austin

Pamela

₩165,299 total

includes taxes & fees

Nov 15 - Nov 16

A hotel with a parking lot, multiple vehicles, and a well-maintained lawn.

16. Best Western Plus Albert Lea I-90/I-35 Hotel

Albert Lea

Patricia

₩123,647 total

includes taxes & fees

Nov 29 - Nov 30

A hotel with a large building, a body of water in the foreground, and trees around.

17. Holiday Inn Express Hotel and Suites Mankato East by IHG

Mankato

Dale

₩134,784 total

includes taxes & fees

Dec 13 - Dec 14

A bar area with a large vase of flowers, two lit candles, and a glass of whiskey on the counter.

18. St James Hotel, a Historic Hotel of America

Red Wing

Daniel

₩206,806 total

includes taxes & fees

Nov 18 - Nov 19

A modern living room with a sectional sofa, red armchairs, a coffee table, and a fireplace.

19. Country Inn & Suites by Radisson, Albert Lea - Austin

Albert Lea

Gail

₩122,743 total

includes taxes & fees

Dec 13 - Dec 14

An outdoor seating area with colorful striped sofas and yellow chairs, a fire pit, and a covered patio with string lights.

20. Home2 Suites by Hilton Rochester Mayo Clinic Area

Rochester

howard

₩168,632 total

includes taxes & fees

Dec 13 - Dec 14

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Vacation Rentals in Southern Minnesota

Aparthotel

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

The Berkman

Folwell

"Excellent service and wonderful room!"

Apartment

A modern living room with a white sofa, a black coffee table, a TV, and a decorative chair.

Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester

"Clean room and great location"

Apartment

A wooden deck with Adirondack chairs lined up against a building with a flag.

Pet-friendly Wabasha Studio: Boat, Ski & Explore!

Wabasha

"Great property! Very convenient location as well."

Apartment

A cafe with outdoor seating, a large tree, and a view of the water.

Lake Pepin Escape: Loft Cottage & Fireplace

Pepin

"Great location and very well furnished with new appliances."

Apartment

A deck with two wooden chairs and a fire pit.

1 Block to Lake City Marina: Condo w/ Rooftop Deck

Lake City

"Wonderful property, spacious, well-appointed and comfortable. Would definitely rent again."

Apartment

A green house with a sloped roof, solar panels, a front porch, and a small garden area.

Downtown Northfield Apt: Winter Walk & Shops

Northfield

"It was amazing!"

Cottage

A calm lake with a dock extending into the water, surrounded by rocky terrain and a distant green hill.

Lake City Retreat Near Wineries & State Park

Lake City

Cottage

A modern interior with a stone fireplace, wooden walls, a leather sofa, and a dining area.

Pet-friendly Cabin Retreat: Walk to Lake Pepin!

Pepin

"What a fun place! Plenty of room. We played foosball had a fire outside. We enjoyed the fireplace too. We hadn’t anticipated no TV though. You might want to add that to your description. The water is definitely smelly, so we truly appreciated the 40 bottles of water you provided. Definitely a great place for a girl’s weekend or family reunion!"

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Stay near popular Southern Minnesota attractions

Mayo Civic Center

9.2/10 (818 reviews)

Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops.

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Learn more about Southern Minnesota

Discover the family-friendly area of Southern Minnesota—an opera house, a college vibe, and sights from Mount Kato Ski Area to Blakeslee Stadium.

See all hotels in Southern Minnesota

A lake surrounded by dense forest and a distant hill with a fort.

Top Southern Minnesota Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent

"I love the swimming pool"

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent

"Easy inconvenient, unloading, unloading area, beautiful entry as I walked in. I was greeted at the desk. Did my transaction for the hotel room and got my executive suites! It was perfect, right where I wanted it in the corne,. And away from everybody, the pull was great, full of clean in excellent. Had a great day"

St James Hotel, a Historic Hotel of America

10/10 Excellent

"Great stay. The room was fantastic, we did room service for supper something I never do. It was at our door in no time after ordering. The food was very reasonable and very satisfying. If or looking for a quick getaway to Red Wing you can't beat the St James."