A cityscape with a river, bridges, and a red trolley.

Search Guest Houses in Southwest Pennsylvania

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3

Our top choices for Southwest Pennsylvania guest houses

A spacious bedroom with a large bed, a wooden chest, a round coffee table, and a fireplace.

1. Deer Creek Winery at Watson Estate

Deer Creek Winery at Watson Estate
3.0 star property
Uniontown
9.0 out of 10, Wonderful, (750 reviews)
"Yes, we were warmly welcomed by staff! Breakfast was fantastic!"
United States
Lynn
The price is ₩224,678
₩249,388 total
includes taxes & fees
Nov 23 - Nov 24
Deer Creek Winery at Watson Estate
Three stained glass windows with a landscape scene.

2. Thistledown At Seger House

Thistledown At Seger House
3.0 star property
Ligonier
9.4 out of 10, Exceptional, (77 reviews)
"Easy check in, very clean facility, room was excellent and the bed was comfortable. Very vintage and modern feel. Will absolutely stay again."
United States
William
The price is ₩235,146
₩261,012 total
includes taxes & fees
Nov 5 - Nov 6
Thistledown At Seger House
A patio with outdoor seating and a pool.

3. The Jacqueline House of Wilmington

The Jacqueline House of Wilmington
3.5 star property
New Wilmington
10.0 out of 10, Exceptional, (143 reviews)
"Excellent place to stay"
United States
Toni
The price is ₩241,864
₩268,469 total
includes taxes & fees
Nov 5 - Nov 6
The Jacqueline House of Wilmington
A lakeside cabin with a balcony, surrounded by trees and a calm water body.

4. Applebutter Inn

Applebutter Inn
3.0 star property
Slippery Rock
8.6 out of 10, Excellent, (102 reviews)
"Applebutter Inn is a breath of fresh air! The historic and cozy building is a welcome change from chain hotels. Julie is so kind and hospitable, we felt like old friends by the time we left. We were all charmed by her companion, Chiquita Banana, who is the sweetest pup you'll ever meet! Our room was immaculate and comfortable. We hope to make it back to Slippery Rock some day, and will definitely stay at Applebutter Inn again!"
United States
Ellen
The price is ₩243,208
₩269,961 total
includes taxes & fees
Nov 23 - Nov 24
Applebutter Inn
A covered outdoor area with a garden, columns, and a building in the background.

5. Modern Homestead Guest House

Modern Homestead Guest House
3.5 star property
Reedsville
9.0 out of 10, Wonderful, (48 reviews)
"Very cute and sweet place."
United States
dulce
The price is ₩172,933
₩185,038 total
includes taxes & fees
Nov 15 - Nov 16
Modern Homestead Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southwest Pennsylvania Hotel Reviews

Omni William Penn Hotel

Omni William Penn Hotel

10/10 Excellent
"Wonderful stay, beautiful hotel and having so many amenities was wonderful. Staff was helpful and kind"
Rowan 2-night trip
Posted 4 hours ago
Omni William Penn Hotel

Find out more about Southwest Pennsylvania

Southwest Pennsylvania Guest Houses information

Number of reviews
1,043
Accommodation
1 Guest Houses
Lowest Price
₩185,038
Highest Price
₩269,961