Southhampton, MO
St. Louis
Visit Southhampton
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Washington University in St. Louis
Enjoy the collegiate vibe at Washington University in St. Louis during your stay in St. Louis. Amble around the area's lush forest or attend a sporting event.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Southhampton Hotel Deals
21C Museum Hotel St Louis
Great hotel! Art, food and drinks were fantastic
Reviewed on Jan 18, 2026
Clayton Plaza Hotel & Extended Stay
All the employees were friendly and welcoming. The breakfast is amazing
Reviewed on Jan 18, 2026
Drury Plaza Hotel St. Louis at the Arch
Our room was cold. Two walls full of glass being a corner room. Lots of traffic noise and garbage pickup at 5-6am. We were on the second floor. Wanted a room higher but the bank of elevators were not working at check in time.
Reviewed on Jan 17, 2026
Hyatt Regency St. Louis at The Arch
Very clean rooms the staff was excellent and ver helpful and friendly. Being so close to the arch was wonderful for views at night 100/10 recommend
Reviewed on Jan 20, 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Everything was great the customer service rep at the desk exceptional customer service.
Reviewed on Jan 18, 2026
Pear Tree Inn St. Louis Near Union Station
Nice breakfast. Clean comfortable room.
Reviewed on Jan 22, 2026
Other neighborhoods around Southhampton
Tower Grove South
When in Tower Grove South, you can plan a visit to Missouri Botanical Gardens and Arboretum and Cherokee Street, some noteworthy sights in the nearby area.
The Hill
If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Dogtown
If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Benton Park
If you're spending some time in Benton Park, Cherokee Street and Cherokee Antique Row are top sights worth seeing.
