A coastal fortress with a stone wall and a tiled-roof building.

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Check availability on Syracuse Luxury Hotels

Tonight
Sep 18 - Sep 19
Tomorrow
Sep 19 - Sep 20
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Syracuse luxury hotels

1. Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Ortigia
  • Discover the epitome of Mediterranean luxury steps from Ortigia's coastline at this spa-focused retreat with poolside indulgence.
₩973,543
₩1,086,627 total
includes taxes & fees
Sep 30 - Oct 1
Grand Hotel Des Ètrangers - The Leading Hotels of the World

2. Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection
Ortigia
  • Relax in a grand Beaux Arts hotel in Ortigia, where upscale comfort meets historic charm steps from Syracuse Cathedral.
₩557,101
₩628,540 total
includes taxes & fees
Sep 27 - Sep 28
Palazzo Artemide - VRetreats, SLH Collection

3. Ortea Palace Hotel, Sicily, Autograph Collection

Ortea Palace Hotel, Sicily, Autograph Collection
Ortigia
  • Mediterranean luxury awaits at this 5-star Syracuse hotel with spa, sauna, and two restaurants near Ortigia's beaches.
₩800,740
₩896,543 total
includes taxes & fees
Oct 14 - Oct 15
Ortea Palace Hotel, Sicily, Autograph Collection

4. Charme Hotel Henry's House

Charme Hotel Henry's House
Ortigia
  • Luxurious Mediterranean retreat offers memory foam beds, designer toiletries, and sea-view rooftop terrace in Ortigia.
₩502,342
₩568,365 total
includes taxes & fees
Oct 17 - Oct 18
Charme Hotel Henry's House

5. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
Ortigia
  • Historic charm meets seaside luxury in Syracuse with private balconies, rainfall showers, and sea-view breakfast.
₩497,368
₩562,894 total
includes taxes & fees
Oct 17 - Oct 18
Algila' Ortigia Charme Hotel

6. Minareto

Minareto
Syracuse
  • Syracuse seaside splendor offers indulgent relaxation with private beach access, beachfront dining, and Art Deco elegance.
₩626,451
₩704,885 total
includes taxes & fees
Sep 21 - Sep 22
Minareto

7. Wellness & Spa Hotel Principe di Fitalia

Wellness & Spa Hotel Principe di Fitalia
Syracuse
  • Sicilian spa escape boasts 2 outdoor pools and a serene full-service wellness center.
₩607,911
₩684,491 total
includes taxes & fees
Oct 5 - Oct 6
Wellness & Spa Hotel Principe di Fitalia

8. Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa
Ortigia
  • Experience luxury at grand hotel with spa services, private beach, and seaside dining in Ortigia.
₩489,023
₩553,654 total
includes taxes & fees
Oct 7 - Oct 8
Grand Hotel Ortigia Siracusa

9. Dimora Caiammari Luxury Hotel & Spa

Dimora Caiammari Luxury Hotel & Spa
Syracuse
  • Coastal luxury awaits at this five-star retreat offering a full-service spa, two outdoor pools, and Mediterranean dining near Fanusa Beach.
₩452,359
₩513,383 total
includes taxes & fees
Sep 22 - Sep 23
Dimora Caiammari Luxury Hotel & Spa

10. Caportigia Boutique Hotel

Caportigia Boutique Hotel
Santa Lucia
  • Elegant Mediterranean luxury, impeccable service, and fine dining near Ortigia await at this boutique Syracuse hotel.
₩322,967
₩371,052 total
includes taxes & fees
Oct 1 - Oct 2
Caportigia Boutique Hotel
View all properties

Top Syracuse Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"This place was great! Awesome location!! Breakfast was delicious!"
Robert 2-night trip
Posted 11 hours ago
Algila' Ortigia Charme Hotel
Grande Albergo Alfeo

Grande Albergo Alfeo

10/10 Excellent
"The hotel is very nice and the staff were very helpful. It’s very close to the main attractions and restaurants. Breakfast was very good and nice view in the rooftop."
Bernie 3-night trip
Posted 2 days ago
Grande Albergo Alfeo
Charme Hotel Henry's House

Charme Hotel Henry's House

10/10 Excellent
"L"
Anthony 3-night trip
Posted 2 days ago
Charme Hotel Henry's House
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Clean & beautifully maintained hotel. Better for those who prefer a larger setting than a boutique hotel. Small but comfortable pool area. Great rooftop with amazing sunset views and kudos to our wonderful waiter Fabio."
Laura 3-night trip
Posted 2 days ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World
 Palazzo Artemide - VRetreats, SLH Collection

Palazzo Artemide - VRetreats, SLH Collection

10/10 Excellent
"El mejor de Ortigia"
William 2-night trip
Posted 2 days ago
Palazzo Artemide - VRetreats, SLH Collection
Grand Hotel Villa Politi

Grand Hotel Villa Politi

8/10 Good
"It had the old historic charm. The price was a good value for the room. If ever gets a remodel as it needs some Upgrading them then the price would be much higher. Nice pool. Staff needs to be a little more helpful and friendly."
Denise 1-night trip
Posted 5 days ago
Grand Hotel Villa Politi
Eureka Palace Hotel Spa

Eureka Palace Hotel Spa

8/10 Good
"The rooms were spacious and clean. The spa was also very good and well maintained"
IKECHUKWU 6-night trip
Posted 12 days ago
Eureka Palace Hotel Spa
Hotel Parco delle Fontane

Hotel Parco delle Fontane

10/10 Excellent
"Please clarify the specific procedures or instructions for gaining access to the facility, particularly regarding the address displayed at the gate."
Salvatore 1-night trip
Posted 3 weeks ago
Hotel Parco delle Fontane

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Syracuse?
Travel to Fontanarossa Airport (CTA) Airport or Vincenzo Magliocco Airport (CIY) Airport, and then treat yourself to a stay at one of 9 Syracuse luxury hotels. While you're visiting, you might want to think about enjoying the ruins and sightseeing, which Syracuse is known for.
What's the best high-end place to stay in Syracuse?
Ortea Palace Hotel, Sicily, Autograph Collection is a luxury hotel with 2 restaurants and a full-service spa, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Grand Hotel Ortigia Siracusa and Grand Hotel Des Ètrangers - The Leading Hotels of the World are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Syracuse?
Lie in the lap of luxury during your getaway to Syracuse in one of Expedia's 9 luxury hotels.
When can I expect good weather in Syracuse?
Planning for the weather is a good way to make your trip to Syracuse relaxing and enjoyable, especially when you're splurging. The hottest months are usually August and July with an average temp of 78°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Syracuse is 26 inches.
What's there to see and do in Syracuse?
Experience all that Syracuse has to offer when you visit Temple of Apollo, Lungomare di Ortigia, and Piazza del Duomo. If you have a little extra time during your trip, you might want to check out Cathedral of Syracuse and Teatro dei Pupi.
How can I get around Syracuse?
It's easier to get around town in style when you know your options. To explore the surrounding area, ride one of the trains from Syracuse Station or Targia Station.

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