A bench, a bicycle, and a lake surrounded by trees.

Find Resorts & Hotels with Spas in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Resorts & Hotels with Spas

Tonight
Oct 22 - Oct 23
Tomorrow
Oct 23 - Oct 24
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Upstate South Carolina hotels with a spa

A spa room with two beds, a mural, and a reception desk.
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A modern interior with a stone fireplace, seating areas, and a unique ceiling design.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
₩464,328
₩526,083 total
includes taxes & fees
Nov 15 - Nov 16
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.
A cozy lounge area with leather armchairs, a central table, and a fireplace.
A modern interior with a large window, a chandelier, a dining area, and a hallway leading to a door.

2. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
₩218,046
₩290,824 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A swimming pool with lounge chairs and a building with balconies.
A bar with a large window view of mountains and a chandelier.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
₩555,866
₩611,453 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Domestique
A hotel room with two beds, wooden walls, and a window.
A rustic cabin with a covered porch, surrounded by trees.
A rustic wooden room with a wooden door, a small table with a lamp, a chair, and a window with curtains.
A cozy wooden cabin bedroom with a bed, a wooden table, a chair, and a window with curtains.

4. Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant
Lakemont
  • Soak in therapeutic massages and mountain tranquility at this historic boutique hotel nestled near Tallulah Gorge State Park.
₩171,138
₩205,152 total
includes taxes & fees
Oct 25 - Oct 26
Lake Rabun Hotel & Restaurant
A hotel room with a bed, a bedside lamp, and a small table with candles.
A spacious dining area with multiple tables and chairs, large windows, and ornate chandeliers.
A lakeside lodge with outdoor seating and string lights.
A stone staircase leading to a house with a stone chimney and a small glass door.

5. Greystone Inn

Greystone Inn
Lake Toxaway
  • Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
₩436,468
₩532,239 total
includes taxes & fees
Nov 15 - Nov 16
Greystone Inn
A reception desk with a logo above it, a white bust sculpture, and a vase with pampas grass.
A modern kitchen with white cabinets, a stainless steel sink, and a wooden staircase leading to a balcony.
A bedroom with a bed, a nightstand, a window with curtains, and a view of the outside.
A bedroom with a bed, a nightstand, a lamp, and a view of a balcony with outdoor furniture.

6. SKYLARANNA Resort & Spa

SKYLARANNA Resort & Spa
Hendersonville
  • Rejuvenate in a mountain spa retreat with 3 dedicated treatment rooms, hot tubs, and aromatherapy services along a scenic river.
₩177,307
₩244,787 total
includes taxes & fees
Oct 25 - Oct 26
SKYLARANNA Resort & Spa
Exterior
Interior
Interior
Terrace/patio

7. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
₩397,995
₩448,739 total
includes taxes & fees
Nov 8 - Nov 9
Bed & Breakfast on Tiffany Hill
A hotel room with two beds, a desk, a chair, a mirror, and a window with curtains.
A covered porch with a view of a street, two potted plants, and an American flag.
A dining area with checkered flooring, multiple tables and chairs, and a decorative cabinet with various items.
A bedroom with a bed, a ceiling fan, a bedside table, and a nightstand.

8. 1898 Waverly Inn

1898 Waverly Inn
Hendersonville
  • Experience spa bliss at this charming B&B with relaxing massage treatment rooms and attentive staff who ensure a rejuvenating stay.
₩210,937
₩237,831 total
includes taxes & fees
Nov 19 - Nov 20
1898 Waverly Inn
A two-story wooden cabin with a balcony, a swimming pool, and a deck area.
A covered porch with rocking chairs and a small table with flowers.
A cozy room with a bed, a chair, a tray with snacks and wine, and a view of the outdoors.
A two-story wooden house with a porch, surrounded by dense forest.

9. Glen-Ella Springs Hotel & Restaurant

Glen-Ella Springs Hotel & Restaurant
Clarkesville
  • Relaxing country retreat with in-room massages and a serene garden setting for a rejuvenating spa experience.
₩279,392
₩319,550 total
includes taxes & fees
Oct 25 - Oct 26
Glen-Ella Springs Hotel & Restaurant
A round table set for four with wicker chairs, a white tablecloth, and a view of a forested area through large windows.
A bedroom with two beds, wooden headboard panels, and a window with a view.
A cozy living room with a large window, a fireplace, and various plants.
A bathroom with a shower area, a toilet, and a sink.

10. Sylvan Falls Mill B&B

Sylvan Falls Mill B&B
Rabun Gap
  • Serene mountain retreat offers restorative massages in a garden setting, steps away from Chattahoochee National Forest.
₩264,003
₩312,877 total
includes taxes & fees
Oct 28 - Oct 29
Sylvan Falls Mill B&B
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Choose what matters most at spa hotels in Upstate South Carolina

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Upstate South Carolina Hotel Reviews

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