A bench, a bicycle, and a lake surrounded by trees.

Find Resorts & Hotels with Spas in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Resorts & Hotels with Spas

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Upstate South Carolina hotels with a spa

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (569 reviews)
  • cleanliness
    Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
The price is ₩463,953
₩525,658 total
includes taxes & fees
Nov 22 - Nov 23
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.

2. Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (875 reviews)
  • cleanliness
    Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
The price is ₩217,869
₩290,588 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.

3. Hotel Domestique

Hotel Domestique
4.0 star property
Travelers Rest
9.8 out of 10, Exceptional, (36 reviews)
  • cleanliness
    Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
The price is ₩555,418
₩610,960 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Domestique
A wooden deck with outdoor seating, surrounded by trees.

4. Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant
4.0 star property
Lakemont
9.0 out of 10, Wonderful, (686 reviews)
  • cleanliness
    Soak in therapeutic massages and mountain tranquility at this historic boutique hotel nestled near Tallulah Gorge State Park.
The price is ₩171,000
₩204,988 total
includes taxes & fees
Nov 1 - Nov 2
Lake Rabun Hotel & Restaurant
A hotel room with a bed, a bedside lamp, and a small table with candles.

5. Greystone Inn

Greystone Inn
3.5 star property
Lake Toxaway
9.4 out of 10, Exceptional, (102 reviews)
  • cleanliness
    Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
The price is ₩436,116
₩531,810 total
includes taxes & fees
Nov 23 - Nov 24
Greystone Inn
A two-story house with a covered porch, a front entrance, and a landscaped garden.

6. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
4.0 star property
Mills River
10.0 out of 10, Exceptional, (1 review)
The price is ₩397,674
₩448,378 total
includes taxes & fees
Nov 8 - Nov 9
Bed & Breakfast on Tiffany Hill
A hotel room with two beds, a desk, a chair, a mirror, and a window with curtains.

7. 1898 Waverly Inn

1898 Waverly Inn
3.0 star property
Hendersonville
9.4 out of 10, Exceptional, (314 reviews)
  • cleanliness
    Experience spa bliss at this charming B&B with relaxing massage treatment rooms and attentive staff who ensure a rejuvenating stay.
The price is ₩184,256
₩207,748 total
includes taxes & fees
Nov 1 - Nov 2
1898 Waverly Inn
A wooden bridge over a small water feature with a large water wheel in the background.

8. Sylvan Falls Mill B&B

Sylvan Falls Mill B&B
3.0 star property
Rabun Gap
9.6 out of 10, Exceptional, (78 reviews)
  • cleanliness
    Serene mountain retreat offers restorative massages in a garden setting, steps away from Chattahoochee National Forest.
The price is ₩263,790
₩312,624 total
includes taxes & fees
Oct 29 - Oct 30
Sylvan Falls Mill B&B
A golf course with a clubhouse, multiple buildings, and a large swimming pool.

9. SKYLARANNA Resort & Spa

SKYLARANNA Resort & Spa
3.5 star property
Hendersonville
8.2 out of 10, Very good, (409 reviews)
  • cleanliness
    Rejuvenate in a mountain spa retreat with 3 dedicated treatment rooms, hot tubs, and aromatherapy services along a scenic river.
The price is ₩177,164
₩244,589 total
includes taxes & fees
Oct 29 - Oct 30
SKYLARANNA Resort & Spa
A two-story wooden cabin with a balcony, a swimming pool, and a deck area.

10. Glen-Ella Springs Hotel & Restaurant

Glen-Ella Springs Hotel & Restaurant
3.5 star property
Clarkesville
9.6 out of 10, Exceptional, (121 reviews)
  • cleanliness
    Relaxing country retreat with in-room massages and a serene garden setting for a rejuvenating spa experience.
The price is ₩279,167
₩319,292 total
includes taxes & fees
Nov 1 - Nov 2
Glen-Ella Springs Hotel & Restaurant
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Upstate South Carolina

Pool
Breakfast included

Top Upstate South Carolina Hotel Reviews

Hilton Greenville

Hilton Greenville

10/10 Excellent
"Location is great for getting to/from downtown area"
William 1-night trip
Posted 4 days ago
Hilton Greenville