A bench, a bicycle, and a lake surrounded by trees.

Find Resorts & Hotels with Spas in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Resorts & Hotels with Spas

Tonight
Oct 25 - Oct 26
Tomorrow
Oct 26 - Oct 27
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Upstate South Carolina hotels with a spa

A spa room with two beds, a mural, and a reception desk.
A modern interior with a fireplace, plush seating, and a stone accent wall.
A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.
A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

1. Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
Greenville Downtown
  • Escape to a Tudor retreat with a full-service spa and rooftop garden overlooking the scenic river in Greenville.
₩463,082
₩524,670 total
includes taxes & fees
Nov 22 - Nov 23
Grand Bohemian Lodge Greenville, Autograph Collection
A modern hotel lobby with a chandelier, wooden shelving, a reception desk, and a view of the outdoors.
A restaurant with a bar area, green upholstered seating, and a view of trees through large windows.
A cozy lounge area with leather armchairs, a central table, and a fireplace.
A large, two-story house with a symmetrical facade, large windows, and a central entrance.

2. Hotel Hartness

Hotel Hartness
Greenville
  • Indulge in rejuvenating treatments at this upscale hotel with six couples spa rooms and scenic hiking trails for a peaceful escape.
₩217,461
₩290,044 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Hartness
A two-story house with a tiled roof, a stone fire pit, and outdoor seating.
A spacious room with wooden beams, a large chandelier, and a cozy seating area with orange chairs and a white sofa.
A reception area with a wooden reception desk, a large abstract painting, and a potted plant.
A swimming pool with lounge chairs and a building with balconies.

3. Hotel Domestique

Hotel Domestique
Travelers Rest
  • Retreat to this mountain hotel with therapeutic massage treatments, sauna, and seasonal outdoor pool for deep relaxation.
₩554,375
₩609,812 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Domestique
A two-story house with a covered porch, a front entrance, and a landscaped garden.
A couple standing in a room with wooden flooring, a chandelier, and a dining area with chairs and a table.
Interior
A kitchen with a central island, white cabinets, and a person preparing food.

4. Bed & Breakfast on Tiffany Hill

Bed & Breakfast on Tiffany Hill
Mills River
₩396,927
₩447,536 total
includes taxes & fees
Nov 8 - Nov 9
Bed & Breakfast on Tiffany Hill
A hotel room with two beds, wooden walls, and a window.
A rustic wooden room with a wooden door, a small table with a lamp, a chair, and a window with curtains.
A cozy wooden cabin bedroom with a bed, a wooden table, a chair, and a window with curtains.
A stone pathway leading to a rustic wooden building surrounded by trees.

5. Lake Rabun Hotel & Restaurant

Lake Rabun Hotel & Restaurant
Lakemont
  • Soak in therapeutic massages and mountain tranquility at this historic boutique hotel nestled near Tallulah Gorge State Park.
₩170,679
₩204,603 total
includes taxes & fees
Oct 29 - Oct 30
Lake Rabun Hotel & Restaurant
A hotel room with a bed, a bedside lamp, and a small table with candles.
A spacious dining area with multiple tables and chairs, large windows, and ornate chandeliers.
A stone staircase leading to a house with a stone chimney and a small glass door.
A swimming pool with lounge chairs and umbrellas, surrounded by autumn trees and a lake view.

6. Greystone Inn

Greystone Inn
Lake Toxaway
  • Soak in mountain views at this lakeside retreat with couples' spa treatment rooms, yoga classes, and deep-tissue massages.
₩435,297
₩530,811 total
includes taxes & fees
Nov 23 - Nov 24
Greystone Inn
A two-story wooden cabin with a balcony, a swimming pool, and a deck area.
A covered porch with rocking chairs and a small table with flowers.
A wooden interior with tables and chairs, a fireplace, and a stone wall.
A two-story wooden house with a porch, surrounded by dense forest.

7. Glen-Ella Springs Hotel & Restaurant

Glen-Ella Springs Hotel & Restaurant
Clarkesville
  • Relaxing country retreat with in-room massages and a serene garden setting for a rejuvenating spa experience.
₩278,643
₩318,693 total
includes taxes & fees
Oct 26 - Oct 27
Glen-Ella Springs Hotel & Restaurant
A hotel room with two beds, a desk, a chair, a mirror, and a window with curtains.
A bedroom with a four-poster bed, a fireplace, a television, and a bathroom visible through an open door.
A two-story house with a porch, a guest house, and a well-maintained garden.
A covered porch with a view of a street, two potted plants, and an American flag.

8. 1898 Waverly Inn

1898 Waverly Inn
Hendersonville
  • Experience spa bliss at this charming B&B with relaxing massage treatment rooms and attentive staff who ensure a rejuvenating stay.
₩197,140
₩222,276 total
includes taxes & fees
Oct 27 - Oct 28
1898 Waverly Inn
A round table set for four with wicker chairs, a white tablecloth, and a view of a forested area through large windows.
A bathroom with a shower area, a toilet, and a sink.
A cozy living room with a large window, a fireplace, and various plants.
A bedroom with two beds, wooden headboard panels, and a window with a view.

9. Sylvan Falls Mill B&B

Sylvan Falls Mill B&B
Rabun Gap
  • Serene mountain retreat offers restorative massages in a garden setting, steps away from Chattahoochee National Forest.
₩263,295
₩312,038 total
includes taxes & fees
Oct 28 - Oct 29
Sylvan Falls Mill B&B
A massage therapy session in a spa setting with a massage table, towels, and various spa products.
A rooftop pool area with lounge chairs, a gazebo, and string lights.
A modern kitchen with a central island, a dining area with a table and chairs, and a staircase with wooden steps.
A spacious room with a large sliding glass door leading to an outdoor area, a ceiling fan, and a dark-colored sofa.

10. SKYLARANNA Resort & Spa

SKYLARANNA Resort & Spa
Hendersonville
  • Rejuvenate in a mountain spa retreat with 3 dedicated treatment rooms, hot tubs, and aromatherapy services along a scenic river.
₩176,831
₩244,132 total
includes taxes & fees
Oct 26 - Oct 27
SKYLARANNA Resort & Spa
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Choose what matters most at spa hotels in Upstate South Carolina

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Excellent Breakfast!"
SHANMUGAM 1-night trip
Posted 22 hours ago
Embassy Suites Greenville Golf Resort & Conference Center
Hilton Greenville

Hilton Greenville

10/10 Excellent
"Location is great for getting to/from downtown area"
William 1-night trip
Posted 2 days ago
Hilton Greenville

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