A street with houses, a water tower, and a banana tree.

Des Peres, St. Louis hotel rooms at the OYO Rooms

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 9 - Aug 10
Tomorrow
Aug 10 - Aug 11
Next weekend
Aug 14 - Aug 16
In two weeks
Aug 21 - Aug 23
Save an average of 15% on thousands of hotels when you're signed in

Top Des Peres Hotel Reviews

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"The room was amazing and super clean and the staff was extremely friendly"
Dion 1-night trip
Posted less than an hour ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

8/10 Good
"The staff and hotel itself were great. The location and homeless people all around it aren’t the best. And just Valet park, might be a little more money but you at least know your car is safe."
Austin 1-night trip
Posted 1 hour ago
Home2 Suites by Hilton St. Louis Downtown
 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

10/10 Excellent
"The hotel is beautiful and in a great location. There is a huge gorgeous park across the street with walking/running paths, and the neighborhood has restaurants and shops nearby. My king suite room was huge and very comfortable. The pool is very nice with plenty of lounge chairs and tables. Staff were so friendly and helpful. I look forward to staying here again!"
Shaun 1-night trip
Posted 3 hours ago
The Royal Sonesta Chase Park Plaza St. Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

8/10 Good
"Outstanding staff were courteous, kind, competent."
Mary 1-night trip
Posted 14 hours ago
Pear Tree Inn St. Louis Near Union Station
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"Staff was friendly. Breakfast was good. Bed was comfortable. Building seemed a little dirty in the common areas."
April 1-night trip
Posted 16 hours ago
Clayton Plaza Hotel & Extended Stay
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"We saw a concert at the amphitheater and spent the night there. Had late night pizza and cookies afterwards at the daiquiri place. Good experience."
Susan 1-night trip
Posted 19 hours ago
Hollywood Casino & Hotel St. Louis
River City Casino & Hotel

River City Casino & Hotel

10/10 Excellent
"Very clean room and staff was very friendly."
Errin 1-night trip
Posted 21 hours ago
River City Casino & Hotel

Explore a world of travel with Expedia