A tropical island with palm trees and a clear blue sky.

Resorts & Hotels with Spas in Panama from ₩162,183

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Top Cities in Panama

A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.
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Panama City

Panama City

Check availability on Panama Resorts & Hotels with Spas

This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Panama hotels with a spa

A modern reception area with a large window, a geometric patterned floor, and two potted plants.

1. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
The price is ₩329,660
₩362,626 total
includes taxes & fees
Dec 4 - Dec 5
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

2. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen Airport
8.6 out of 10, Excellent, (2,777 reviews)
The price is ₩182,742
₩209,884 total
includes taxes & fees
Nov 8 - Nov 9
Crowne Plaza Panama Airport by IHG
A lobby with a central table, potted plants, and a modern ceiling design.

3. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (770 reviews)
  • cleanliness
    Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
The price is ₩422,255
₩464,487 total
includes taxes & fees
Nov 27 - Nov 28
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern hotel lobby with a reception desk, seating area, and a hallway with decorative elements.

4. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.2 out of 10, Wonderful, (1,003 reviews)
The price is ₩239,508
₩263,459 total
includes taxes & fees
Dec 4 - Dec 5
Marriott Panama Hotel
A hotel room with a large window offering a city view, a bed, a chair, and a small table with a tray.

5. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Immerse in luxurious tranquility at this Art Deco hotel with 6 treatment rooms and an outdoor pool for a rejuvenating retreat.
The price is ₩284,786
₩313,271 total
includes taxes & fees
Nov 13 - Nov 14
Bristol Panama, a Registry Collection Hotel
A modern lobby with a bar area, seating, and a colorful mural.

6. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.
The price is ₩347,075
₩381,783 total
includes taxes & fees
Nov 22 - Nov 23
W Panama
A room with a bed, a small table with candles, and a shelf with towels.

7. Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall

Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
4.0 star property
Barrio Sur
8.2 out of 10, Very good, (995 reviews)
  • cleanliness
    Rejuvenate at this waterfront hotel featuring couples spa treatments, an outdoor pool, and hot stone massages for a serene escape.
The price is ₩147,443
₩162,183 total
includes taxes & fees
Nov 18 - Nov 19
Radisson Colon 2000 Hotel & Casino at Cruise Port & Duty Free Mall
A hotel room with a checkered floor, a window with white curtains, and a lounge area with chairs and tables.

8. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (771 reviews)
  • cleanliness
    Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
The price is ₩640,940
₩705,034 total
includes taxes & fees
Nov 29 - Nov 30
Sofitel Legend Casco Viejo, Panama City
A spa area with a hot tub, candles, and a curved bench.

9. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Immerse in tranquility at this Art Deco resort with two treatment rooms for couples and a Turkish bath, where expert spa therapists await.
The price is ₩260,004
₩286,004 total
includes taxes & fees
Nov 15 - Nov 16
Sheraton Grand Panama
A reception desk with a logo, a patterned wall, and a potted plant.

10. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
The price is ₩307,813
₩338,594 total
includes taxes & fees
Nov 6 - Nov 7
Hilton Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Principe Hotel and Suites

Principe Hotel and Suites

8/10 Good
"Clean and spacious rooms."
Benjamin 5-night trip
Posted 5 hours ago
Principe Hotel and Suites

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