A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Our top choices for Panama City hotels with a spa

1. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,241 reviews)
"great stay"
Canada
Davlin
The price is ₩157,525
₩173,277 total
includes taxes & fees
Nov 9 - Nov 10
Plaza Paitilla Inn Hotel

2. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (500 reviews)
"Enjoyed our stay"
United States
Mariah
The price is ₩326,831
₩359,514 total
includes taxes & fees
Dec 6 - Dec 7
Hyatt Regency Panama City

3. Casa Bianca

Casa Bianca
2.0 star property
Bella Vista
9.8 out of 10, Exceptional, (8 reviews)
"Good place , nice, clean, "
United States
Jose A
The price is ₩223,302
₩245,632 total
includes taxes & fees
Dec 6 - Dec 7
Casa Bianca

4. Las Clementinas

Las Clementinas
3.5 star property
Casco Viejo
9.4 out of 10, Exceptional, (207 reviews)
"Great food and location"
United States
James
The price is ₩208,316
₩256,305 total
includes taxes & fees
Nov 25 - Nov 26
Las Clementinas

5. Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (600 reviews)
"Hotel is maintained and managed well, close to many restaurants and transportation."
United States
Michael
The price is ₩53,646
₩59,011 total
includes taxes & fees
Nov 16 - Nov 17
Hotel Milan

6. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (6,180 reviews)
"The rooms were great, breakfast was enjoyable"
United States
Ashford J.
The price is ₩176,962
₩194,658 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Riu Plaza Panama

7. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
4.5 star property
Bella Vista
9.0 out of 10, Wonderful, (543 reviews)
"Breakfast was great, and location!!"
United States
Oscar
The price is ₩110,026
₩157,910 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Dann Carlton Marinn Place Panama Financial District

8. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,224 reviews)
"Breakfast, Cafe, was just perfect location"
United States
Bruno
The price is ₩126,739
₩213,176 total
includes taxes & fees
Nov 9 - Nov 10
Waymore Hotel Spa & Casino

9. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is ₩147,258
₩161,984 total
includes taxes & fees
Nov 14 - Nov 15
La Résidence Panamá

10. TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"Decent stay for the money."
Canada
Larry
The price is ₩120,838
₩132,922 total
includes taxes & fees
Nov 16 - Nov 17
TRYP by Wyndham Panamá Centro

11. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,041 reviews)
"Good breakfast and staff"
United States
Travis
The price is ₩108,399
₩119,239 total
includes taxes & fees
Nov 9 - Nov 10
Riande Urban Hotel

12. Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (1,004 reviews)
"Good and very comfortable place to stay and close to everything"
United States
Douglas R Ng
The price is ₩104,531
₩122,451 total
includes taxes & fees
Dec 5 - Dec 6
Holiday Inn Panama Distrito Financiero by IHG

13. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,000 reviews)
"was good"
United States
Juliet
The price is ₩283,854
₩312,246 total
includes taxes & fees
Nov 13 - Nov 14
Bristol Panama, a Registry Collection Hotel

14. Toscana Inn

Toscana Inn
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (792 reviews)
"Wonderful staff,great hotel,perfect location"
Canada
Dalton
The price is ₩87,322
₩96,053 total
includes taxes & fees
Nov 16 - Nov 17
Toscana Inn

15. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
"Perfect location close to the financial district, local markets, and great restaurants."
United States
Simon
The price is ₩339,252
₩373,177 total
includes taxes & fees
Dec 4 - Dec 5
Hilton Panama

16. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
"This was a lovely stay was like sleeping on a luxury ship and the rooms was very luxury very put together for a woman with mirrors and bathrobes lovely shower and nice city view"
United States
Jerome
The price is ₩360,158
₩396,173 total
includes taxes & fees
Dec 6 - Dec 7
W Panama

17. Hotel Coral Suites

Hotel Coral Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,001 reviews)
"Great hotel."
Canada
peter
The price is ₩98,977
₩108,875 total
includes taxes & fees
Nov 12 - Nov 13
Hotel Coral Suites

18. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
"The room was very nice, the bar staff and front desk staff were very helpful."
United States
Oscar
The price is ₩391,178
₩430,296 total
includes taxes & fees
Dec 6 - Dec 7
Waldorf Astoria Panama

19. Hilton Garden Inn Panama City Downtown, Panama

Hilton Garden Inn Panama City Downtown, Panama
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,002 reviews)
"It was the wonderful stay highly recommended. It keeps it downtown, easy access to where you need to go Uber will pick you right in front well manage! Wonderful service great staff!"
United States
carla
The price is ₩121,175
₩133,292 total
includes taxes & fees
Nov 28 - Nov 29
Hilton Garden Inn Panama City Downtown, Panama

20. Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (4 reviews)
"The place is peaceful and its close to restaurants and supermarkets. I would booked dem again in future"
United States
Denesha
The price is ₩102,598
₩112,858 total
includes taxes & fees
Dec 4 - Dec 5
Luxury City View Apartments at Worldwide
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Panama City

Spa hotels with pools in Panama City

Spa hotels with hot tubs in Panama City

Spa hotels with free breakfast in Panama City

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Panama City

Top Panama City attractions for a relaxing vacation

In Panama City, travelers seeking luxurious spa hotels will find a wealth of experiences that cater to relaxation and rejuvenation. Start your journey at the Amador Causeway, where scenic views of the Pacific Ocean and the stunning skyline create a picturesque backdrop for leisurely strolls or bike rides. Nearby, the Biomuseo offers an engaging dive into Panama’s biodiversity and history, allowing for a cultural touch to your stay. For those who enjoy nature, the Metropolitan Natural Park provides a lush escape with walking trails that lead to panoramic views of the city, perfect for unwinding amidst greenery. After a day of exploration, indulge in a spa treatment at one of the city's upscale hotels, such as the Waldorf Astoria Panama, known for its luxurious amenities and exceptional service. The Casco Viejo district, with its charming cobblestone streets and vibrant nightlife, offers a unique blend of history and modernity, making it an exciting area to explore while staying at a boutique hotel that prioritizes guest satisfaction. Each of these experiences ensures a perfect balance of adventure and pampering, allowing for a memorable stay in Panama City.

Find the best hotels & resorts with spas in Panama City

For travelers seeking rejuvenation and relaxation in Panama City, these top hotels offer exceptional spa amenities and tranquil environments for a perfect getaway.

Ramada Plaza By Wyndham Panama Punta Pacífica

  • Why it's great for tailored spa getaway: Ramada Plaza By Wyndham Panama Punta Pacífica is a haven for spa enthusiasts, featuring a dedicated treatment room and a fantastic review rating of 9.6. Guests can unwind in the outdoor pool or indulge in the hotel’s delicious dining options, ensuring a well-rounded experience that focuses on relaxation and enjoyment.
  • Other amenities: In addition to its spa amenities, this hotel provides a complimentary buffet breakfast and features like a 24-hour fitness center, concierge service, and a shopping mall on-site. The hotel’s romantic ambiance and thoughtful touches, like champagne service, make it a wonderful choice for those looking to combine relaxation with a touch of luxury.
  • Neighborhood: San Francisco
  • Nearby attractions: ATLAPA Conventions Center - 0.64 miles, Calle 50 - 0.41 miles, Multiplaza Pacific Mall - 0.21 miles

Plaza Paitilla Inn Hotel

  • Why it's great for tailored spa getaway: Travelers looking for a spa retreat will find Plaza Paitilla Inn Hotel an excellent option, highlighted by a remarkable review rating of 9.4. The hotel offers a range of spa services, including Swedish and hot stone massages, alongside rejuvenating body treatments. The inviting outdoor pool area is perfect for unwinding after a day of pampering.
  • Other amenities: Beyond its spa offerings, guests can enjoy a complimentary buffet breakfast each morning and benefit from amenities such as a fitness center, terrace for relaxation, and convenient on-site shopping. The hotel’s location also provides easy access to the vibrant Punta Paitilla area, enhancing the overall travel experience.
  • Neighborhood: Punta Paitilla
  • Nearby attractions: Avenida Balboa - 0.33 miles, Cinta Costera - 0.48 miles, Multicentro Panama - 0.85 miles

Bristol Panama, a Registry Collection Hotel

  • Why it's great for tailored spa getaway: For travelers seeking an exceptional spa experience, Bristol Panama stands out with an impressive review rating of 9.2. The hotel features a full-service spa offering a diverse range of treatments, including Swedish and prenatal massages, ensuring guests can experience the ultimate in relaxation and rejuvenation. The serene atmosphere of the spa is complemented by an outdoor pool for leisurely afternoons.
  • Other amenities: Guests can also enjoy amenities such as an on-site art gallery, complimentary airport transportation, and a well-equipped fitness center. Additional features include luxurious in-room amenities like Egyptian cotton sheets and minibars, alongside convenient valet parking, making for a truly indulgent stay.
  • Neighborhood: Bella Vista
  • Nearby attractions: Calle 50 - 0.43 miles, Uruguay Street - 0.34 miles, Avenida Balboa - 0.44 miles

Hotel Riu Plaza Panama

  • Why it's great for tailored spa getaway: For travelers who prioritize wellness and relaxation, Hotel Riu Plaza Panama is an ideal choice, an excellent guest review rating of 9.0. The hotel features a full-service spa with treatment rooms, ensuring guests can indulge in various pampering treatments and therapies designed to refresh the body and mind. An outdoor pool also provides a serene setting for relaxation after a spa session.
  • Other amenities: In addition to its spa amenities, guests can enjoy a complimentary buffet breakfast and an array of dining options, including a poolside bar for leisurely afternoons. The hotel also offers convenient amenities such as valet parking, a fitness center, and a shopping district on-site, making it a well-rounded destination for both relaxation and convenience.
  • Neighborhood: Bella Vista
  • Nearby attractions: Calle 50 - 0.0 miles, Uruguay Street - 0.91 miles, Via Espana - 0.61 miles

Top Panama City Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Waymore Hotel Spa & Casino and Decapolis Hotel Panama City.
How many spa hotels are there in Panama City?
Expedia has 21 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Avenida Balboa.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.