Photo by Najib Tecle

Find hotels in Downtown Clayton, St. Louis from ₩145,734

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 16 - Dec 17
Tomorrow
Dec 17 - Dec 18
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown Clayton hotels

Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Downtown Clayton
8.8 out of 10, Excellent, (3034)
"Clean room, good breakfast and good location "
United States
Martin
The price is ₩132,049
₩154,150 total
includes taxes & fees
Dec 21 - Dec 22
Clayton Plaza Hotel & Extended Stay
Front of property
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Downtown Clayton
8.4 out of 10, Very Good, (577)
"Love this place."
United States
Robert
The price is ₩179,163
₩223,059 total
includes taxes & fees
Dec 19 - Dec 20
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Downtown Clayton
8.8 out of 10, Excellent, (678)
"Small rooms but beautiful lobby. "
United States
Debbie
The price is ₩175,051
₩206,103 total
includes taxes & fees
Dec 19 - Dec 20
Le Méridien St. Louis Clayton
Property amenity
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Downtown Clayton
9.0 out of 10, Wonderful, (223)
"Enjoyed my stay"
United States
Kingsley
The price is ₩180,281
₩210,456 total
includes taxes & fees
Dec 28 - Dec 29
AC Hotel St. Louis Clayton
Meeting facility
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is ₩732,806
₩855,459 total
includes taxes & fees
Dec 21 - Dec 22
The Ritz-Carlton, St. Louis
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 13.2 km from Downtown Clayton
8.4 out of 10, Very Good, (4017)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is ₩123,578
₩145,734 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Regency St. Louis at The Arch
Indoor pool, open 6:00 AM to 10:00 PM, sun loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 13.2 km from Downtown Clayton
8.6 out of 10, Excellent, (1174)
"The room was clean and the staff were extremely friendly and personable! "
United States
Shannon
The price is ₩139,806
₩163,473 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
3.4 km from Downtown Clayton
9.0 out of 10, Wonderful, (1917)
"Had a great stay. Everything was good. "
United States
Krystal
The price is ₩169,147
₩201,164 total
includes taxes & fees
Dec 22 - Dec 23
Moonrise Hotel
Front of property
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 13.1 km from Downtown Clayton
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
The price is ₩151,554
₩178,726 total
includes taxes & fees
Dec 22 - Dec 23
Hilton Pennywell St. Louis at the Arch
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
2.2 km from Downtown Clayton
9.4 out of 10, Exceptional, (836)
"We always enjoy our stay here nice clean and great location "
United States
Dominique
The price is ₩148,544
₩182,237 total
includes taxes & fees
Dec 18 - Dec 19
Courtyard by Marriott St. Louis Brentwood
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 12.2 km from Downtown Clayton
7.6 out of 10, Good, (591)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is ₩119,217
₩139,400 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru By Hilton St. Louis Downtown
Property amenity
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 13.1 km from Downtown Clayton
9.4 out of 10, Exceptional, (3285)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is ₩198,240
₩231,800 total
includes taxes & fees
Dec 20 - Dec 21
Drury Plaza Hotel St. Louis at the Arch
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 12.9 km from Downtown Clayton
8.8 out of 10, Excellent, (1243)
"Great hospitality"
United States
Alejandro
The price is ₩157,429
₩187,228 total
includes taxes & fees
Dec 23 - Dec 24
Embassy Suites by Hilton St. Louis Downtown
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
18.5 km from Downtown Clayton
8.4 out of 10, Very Good, (1005)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ₩223,439
₩285,491 total
includes taxes & fees
Dec 21 - Dec 22
Ameristar Casino Resort and Spa
Front of property - evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
17 km from Downtown Clayton
8.4 out of 10, Very Good, (2221)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is ₩154,183
₩201,206 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hollywood Casino & Hotel St. Louis
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 12.8 km from Downtown Clayton
8.8 out of 10, Excellent, (1154)
"Really nice hotel!"
United States
DARIN
The price is ₩128,204
₩152,472 total
includes taxes & fees
Dec 22 - Dec 23
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Reception
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
16.4 km from Downtown Clayton
8.0 out of 10, Very Good, (1042)
"Everything was clean and friendly staff overall good experience "
United States
dennis
The price is ₩124,827
₩144,182 total
includes taxes & fees
Dec 22 - Dec 23
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Lobby
Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West, 11 km from Downtown Clayton
9.2 out of 10, Wonderful, (1002)
"Breakfast menu was fresh and tasty. Will return in the future with more time to go to the national park!"
United States
Silvar
The price is ₩157,135
₩187,511 total
includes taxes & fees
Dec 22 - Dec 23
Fairfield Inn & Suites by Marriott St. Louis Downtown
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
18.8 km from Downtown Clayton
9.4 out of 10, Exceptional, (1007)
"The staff were awesome "
United States
Corey
The price is ₩164,912
₩189,527 total
includes taxes & fees
Dec 28 - Dec 29
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 12.7 km from Downtown Clayton
9.0 out of 10, Wonderful, (1010)
"Was a great stay. "
United States
Lorilyn
The price is ₩148,544
₩176,662 total
includes taxes & fees
Dec 22 - Dec 23
Courtyard by Marriott St. Louis Downtown/Convention Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Top Downtown Clayton Hotel Reviews

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

10/10 Excellent
"I like the hotel."
Qingshu 1-night trip
Posted 2 days ago
Pear Tree Inn St. Louis Airport

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown Clayton?
Travelers to the Downtown Clayton neighborhood in St. Louis will be sure to enjoy their stay.
What's a favorite place to stay in Downtown Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Downtown Clayton. This hotel offers 2 restaurants and 2 bars. Other favorite options in the area include The Ritz-Carlton, St. Louis and Le Méridien St. Louis Clayton.
How many hotels should I expect to find in the Downtown Clayton area?
Expedia has 5 Downtown Clayton hotels and other accommodations, and one might make a good home base for venturing out into the greater St. Louis area.
If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then you can use the "fully refundable" filter to view top deals in Downtown Clayton.
Where can I learn more about changing or cancelling my trip to Downtown Clayton?
For more details about rescheduling or cancelling your trip to Downtown Clayton, go to https://www.expedia.com/service/.
What can I see and do in this St. Louis neighborhood?
Shaw Park Tennis Center, Saint Louis Galleria Mall, and Tao Tennis Center are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Center of Creative Arts and Chapel of St. Timothy And St. Titus, Concordia Seminary are a couple of additional sights to visit in St. Louis.
How can I get around Downtown Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.