Downtown Clayton Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Najib Tecle

  • Plan, book, travel with confidence

    • Better together

    Save up to ₩234,741 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Clayton
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

3 out of top 10 points of interest in this area
4/5(4,004 area reviews)

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Find hotels in Downtown St. Louis

Downtown Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ₩143,889 per night from Nov 2 to Nov 3
₩143,889
₩167,976 total
Nov 2 - Nov 3
includes taxes & fees
8.8/10 Excellent! (2,973 reviews)
Yes

Reviewed on Oct 27, 2025

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ₩187,056 per night from Nov 2 to Nov 3
₩187,056
₩218,366 total
Nov 2 - Nov 3
includes taxes & fees
9/10 Wonderful! (199 reviews)
They had an interesting bar at the top floor that unfortunately we couldn’t try

Reviewed on Oct 20, 2025

AC Hotel St. Louis Clayton
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is ₩207,186 per night from Oct 31 to Nov 1
₩207,186
₩242,261 total
Oct 31 - Nov 1
includes taxes & fees
9.4/10 Exceptional! (3,191 reviews)
10/10
Very clean hotel. Location made many things walkable. Desk staff were friendly and beyond helpful. We had a refrigerator that wasn’t keeping our drinks cold and maintenance arrived to fix it immediately despite it being 8pm. Loved the 5:30 free drinks and food offerings. 10/10 recommend, and we will ...

Reviewed on Oct 21, 2025

Drury Plaza Hotel St. Louis at the Arch
See all 1,750 properties in Downtown Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown Clayton vacation package cost?
Less than you might think — from just , as a matter of fact! By combining hotels, flights and car rentals into a custom-made travel package, your Downtown Clayton escape is just a few clicks away.
How do I get a cheap travel package to Downtown Clayton?
Imagine all the wonderful things you could do in Downtown Clayton with a pile of extra cash in your wallet. Watch your savings stack up when you combine your travel bookings into a Downtown Clayton vacation package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 air carriers and 1,000,000 properties throughout the world. Whether you're taking off with the whole family or surprising your special someone, organizing a trip to Downtown Clayton is better with a package.
Where should I stay in Downtown Clayton?
Most people who visit Downtown Clayton include both St. Louis Zoo and Cathedral Basilica of St. Louis on their bucket lists. Why not go for a hotel that's close to these iconic attractions?
What are the top hotels in Downtown Clayton?
King Bed, Comfy Environment, Cozy Space and Le Méridien St. Louis Clayton are among the most well-known properties in Downtown Clayton. Why not look up the amenities and facilities at each and then decide?
How far in advance should I book my Downtown Clayton vacation?
Your safest bet is to book early. Air carriers generally advertise flights around a year in advance, and this is a fantastic opportunity to land some rock-bottom prices. Just been told you should take all your vacation days next month? That's alright! Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Downtown Clayton travel package include?
That depends on what sort of escape you're planning. Downtown Clayton vacation deals can include car rentals, hotels and flights. You can mix and match to create the package that works for you! You can also add on activities and experiences after you've booked to land even bigger discounts.
What should I know before booking a Downtown Clayton travel package?
When you book your flights, hotels and car rentals together, you'll walk away with fantastic discounts. Whether you're organizing a beach break in a villa or prefer to stay in a convenient hotel in the city, Expedia will make it happen for less.
Can I choose my airline with a Downtown Clayton Expedia vacation package?
Expedia offers access to more than 550 airline partners worldwide, so you sure can! Simply choose your preferred air carrier and create the perfect Downtown Clayton trip.
If I'm not able to travel, can I cancel my Downtown Clayton vacation package?
It's hard to predict what the future holds, so it's good to know that you can change or cancel your Downtown Clayton vacation package. If you booked in the last 24 hours, you may be eligible for a refund. If it's an older booking, your airline, hotel or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Discover the most popular places to visit in Downtown Clayton

Gateway Arch showing a city, a skyscraper and skyline

Gateway Arch

4.5/5(2,511 reviews)

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

4.5/5(1,212 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo
Seeing one of the largest hotels decked out in Rainbow lights in St. Louis is pretty awesome! Lots of food and drink options at this hotel & casino! #LifeAtExpedia

Horseshoe St. Louis Casino

4/5(14 reviews)

Why not roll the dice with a visit to Horseshoe St. Louis Casino during your time in St. Louis? Experience the area's acclaimed art scene or attend a baseball game.

Horseshoe St. Louis Casino
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.