Find hotels near East Cooper Medical Center, Mount Pleasant from ₩134,063

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Our top choices for East Cooper Medical Center hotels

Dinner served, American cuisine
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
2.3 km from East Cooper Medical Center
9.4 out of 10, Exceptional, (1796)
"Pefect stay"
United States
Hayden
The price is ₩135,754
₩156,594 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Cambria Hotel Mount Pleasant – Charleston
Lobby
Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
2.5 star property
2 km from East Cooper Medical Center
9.2 out of 10, Wonderful, (1451)
"It was a great hotel!"
United States
Alashia
The price is ₩116,047
₩134,063 total
includes taxes & fees
Dec 18 - Dec 19
Tru by Hilton Mt Pleasant Charleston
Bar (on property)
Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant
3.5 star property
2.4 km from East Cooper Medical Center
9.2 out of 10, Wonderful, (1000)
"Good value and great location."
United States
Howard
The price is ₩149,455
₩172,194 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hyatt House Charleston / Mount Pleasant
Restaurant
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
2.5 star property
0.3 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (1000)
"Great place to stay!!!"
United States
Fredrick
The price is ₩116,047
₩134,245 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
Bar (on property)
Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre
3.0 star property
0.4 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (1001)
"Nice place"
United States
Marcelle
The price is ₩150,333
₩187,724 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hyatt Place Mount Pleasant Towne Centre
Exterior
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
0.8 km from East Cooper Medical Center
9.0 out of 10, Wonderful, (1001)
"Everything about my stay here has been a delight, clean room, professional & friendly staff "
United States
John
The price is ₩128,941
₩145,702 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
Exterior
Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston
3.0 star property
0.7 km from East Cooper Medical Center
8.8 out of 10, Excellent, (994)
"Specious room and good breakfast "
United States
Binod
The price is ₩139,491
₩157,623 total
includes taxes & fees
Dec 18 - Dec 19
Home2 Suites By Hilton Mt Pleasant Charleston
Free daily full breakfast
Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant
3.0 star property
0.4 km from East Cooper Medical Center
8.8 out of 10, Excellent, (183)
"Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. "
United States
Holly
The price is ₩186,085
₩210,275 total
includes taxes & fees
Dec 17 - Dec 18
Residence Inn by Marriott Charleston Mount Pleasant
Lobby lounge
Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant
3.0 star property
1.9 km from East Cooper Medical Center
8.8 out of 10, Excellent, (1001)
"We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. "
United States
Kathryn
The price is ₩147,989
₩167,229 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard by Marriott Charleston Mount Pleasant
Restaurant
Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant
3.0 star property
1.5 km from East Cooper Medical Center
8.4 out of 10, Very Good, (1002)
"Courteous staff and great location"
United States
Loushon
The price is ₩147,696
₩169,827 total
includes taxes & fees
Dec 21 - Dec 22
Homewood Suites by Hilton Charleston - Mt Pleasant
Exterior
Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector
2.5 star property
0.5 km from East Cooper Medical Center
8.2 out of 10, Very Good, (1002)
"The staff was friendly and the room was exceptionally clean. "
United States
RAYMOND
The price is ₩122,992
₩146,118 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Comfort Suites at Isle Of Palms Connector
Lounge
The Loutrel

The Loutrel

The Loutrel
4.0 star property
11 km from East Cooper Medical Center
10.0 out of 10, Exceptional, (1004)
"Beautiful hotel in a great location "
United States
Sean
The Loutrel
Courtyard
Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston

Hilton Club Liberty Place Charleston
3.5 star property
10.7 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (883)
"Wonderful two bedroom suite and room was cleaned daily - wonderful location as well."
United States
Liz
The price is ₩311,378
₩354,969 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Club Liberty Place Charleston
Lounge
HarbourView Inn

HarbourView Inn

HarbourView Inn
4.0 star property
10.8 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (1004)
"Our room was excellent. Couldn’t have been more pleased with our stay. "
United States
Kyle
HarbourView Inn
Anson Suite | Frette Italian sheets, premium bedding, Tempur-Pedic beds, in-room safe
Zero George Street

Zero George Street

Zero George Street
5.0 star property
10.8 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (353)
"A delightful stay in a delightful setting. "
United States
Tommy
The price is ₩395,636
₩457,723 total
includes taxes & fees
Dec 16 - Dec 17
Zero George Street
Front of property
The Spectator Hotel

The Spectator Hotel

The Spectator Hotel
4.0 star property
11 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (980)
"Excellent 5 star hotel"
United States
John
The Spectator Hotel
Terrace/patio
French Quarter Inn

French Quarter Inn

French Quarter Inn
4.0 star property
11.1 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (1004)
"Phenomenal stay - highly recommend"
United States
Patricia
French Quarter Inn
Reception
The Pinch Hotel

The Pinch Hotel

The Pinch Hotel
4.0 star property
11.3 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (170)
"Large room with great city views. Well stocked mini bar. Front desk was very friendly and helpful. Great location."
United States
Paul
The Pinch Hotel
Terrace/patio
The Nickel Hotel

The Nickel Hotel

The Nickel Hotel
4.0 star property
11.4 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (80)
"Everything about this new hotel is spot on-elegant design and a sweet and attentive staff within a private refuge-despite an often busy central downtown location."
United States
Christine
The price is ₩385,534
₩442,645 total
includes taxes & fees
Dec 15 - Dec 16
The Nickel Hotel
Front of property
20 South Battery

20 South Battery

20 South Battery
3.0 star property
11.8 km from East Cooper Medical Center
9.8 out of 10, Exceptional, (225)
"Beautiful historic boutique hotel with all the southern charms. Comfortable, clean with some nice extra touches like free water and brekky. Also free parking across the street and right near the waterfront. Within walking distance of King Street and restaurants. Would definitely stay here again."
Australia
Justin
The price is ₩369,172
₩484,120 total
includes taxes & fees
Jan 4 - Jan 5, 2026
20 South Battery
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Cooper Medical Center Hotel Reviews

Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

10/10 Excellent
"Pefect stay"
Hayden 2-night trip
Posted 3 days ago
Cambria Hotel Mount Pleasant – Charleston

Hotels near other East Cooper Medical Center attractions

Boone Hall Plantation and Gardens

4.6/5 (518 reviews)
Find out about the history of Mount Pleasant when you take a trip to Boone Hall Plantation and Gardens. Stroll along the area's waterfront, or simply savor its top-notch restaurants.
See properties

Regal Palmetto Grande

You can take time to visit Regal Palmetto Grande during your travels to Mount Pleasant. Wander the area's riverfront or simply enjoy one of its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around East Cooper Medical Center?
East Cooper Medical Center is located in Mount Pleasant. This historic area is known for its beautiful river views and array of dining options. If you're looking for a convenient place to stay, check out the 26 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to East Cooper Medical Center?
Adjacent to East Cooper Medical Center, Hyatt Place Mount Pleasant Towne Centre is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. Other good choices close by include Home2 Suites By Hilton Mt Pleasant Charleston and Comfort Suites at Isle Of Palms Connector.
How many hotels can I expect to find close to East Cooper Medical Center?
Expedia has 26 hotels and other accommodations within a mile from East Cooper Medical Center.
If I need to cancel the hotel reservation for my stay near East Cooper Medical Center, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the top deals on offer near East Cooper Medical Center.
Where can I learn more about changing or cancelling my trip in the area near East Cooper Medical Center?
To find more details about rescheduling or cancelling your stay near East Cooper Medical Center, head over to our customer service page.
What can I see and do near East Cooper Medical Center?
Learn about local history at Charles Pinckney National Historic Site and Pitt Street Bridge. You can enjoy live performances at Crabpot Players Theatre and Cinebarre Mount Pleasant. Spend some time wandering around Shem Creek Park, Mount Pleasant Memorial Waterfront Park, and Palmetto Islands County Park.

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