Find hotels in Greater South Side, Des Moines

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Greater South Side hotels

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1,764 reviews)
"Rooms and bedding was nice and clean."
United States
Wendell
The price is ₩92,431
₩103,522 total
includes taxes & fees
Mar 22 - Mar 23
Days Inn & Suites by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport
2.5 star property
Greater South Side
7.8 out of 10, Good, (1,003 reviews)
"Front desk staff is very friendly and helpful. "
United States
Ann
The price is ₩86,053
₩96,380 total
includes taxes & fees
Mar 22 - Mar 23
AmericInn by Wyndham Des Moines Airport

Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport
2.5 star property
Greater South Side
7.4 out of 10, Good, (1,004 reviews)
"Closest hotel to the airport, and they start hot breakfast at 4:30am."
United States
Sandra
The price is ₩97,103
₩108,756 total
includes taxes & fees
Mar 1 - Mar 2
Quality Inn & Suites Des Moines Airport

Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport
2.5 star property
Greater South Side
8.8 out of 10, Excellent, (1,003 reviews)
"Great room/breakfast!"
United States
Leonard
The price is ₩164,846
₩184,628 total
includes taxes & fees
Mar 1 - Mar 2
Hampton Inn Des Moines-Airport

Holiday Inn Des Moines-Airport/Conf Center by IHG

Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
Greater South Side
8.2 out of 10, Very Good, (622 reviews)
"Great"
United States
Myrthe
The price is ₩166,610
₩186,603 total
includes taxes & fees
Mar 8 - Mar 9
Holiday Inn Des Moines-Airport/Conf Center by IHG

GrandStay Hotel & Suites

GrandStay Hotel & Suites
2.0 star property
14.5 km from Greater South Side
9.4 out of 10, Exceptional, (519 reviews)
"The staff was very welcoming, the room was clean and comfortable and the location worked out well. "
United States
Robert
The price is ₩122,354
₩137,037 total
includes taxes & fees
Feb 24 - Feb 25
GrandStay Hotel & Suites

Tru By Hilton Ankeny

Tru By Hilton Ankeny
2.5 star property
18.1 km from Greater South Side
9.2 out of 10, Wonderful, (144 reviews)
"Great room."
United States
Clinton
The price is ₩132,478
₩148,375 total
includes taxes & fees
Mar 6 - Mar 7
Tru By Hilton Ankeny

Holiday Inn Express Des Moines Ankeny by IHG

Holiday Inn Express Des Moines Ankeny by IHG
2.5 star property
17.5 km from Greater South Side
9.4 out of 10, Exceptional, (309 reviews)
"clean, friendly staff, room was well equipped"
United States
Colin
The price is ₩131,900
₩147,722 total
includes taxes & fees
Mar 12 - Mar 13
Holiday Inn Express Des Moines Ankeny by IHG

Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University
3.0 star property
Drake, 5.6 km from Greater South Side
9.4 out of 10, Exceptional, (1,010 reviews)
"Clean, spacious, great amenities, and the sheets were super soft."
United States
Bryan
The price is ₩129,268
₩144,780 total
includes taxes & fees
Mar 1 - Mar 2
Home2 Suites by Hilton Des Moines at Drake University

Hotel Pommier Indianola

Hotel Pommier Indianola
2.5 star property
20.9 km from Greater South Side
9.2 out of 10, Wonderful, (442 reviews)
"We found every aspect of the stay very good. The great breakfast is what keeps us coming back."
United States
Dean
The price is ₩118,710
₩132,956 total
includes taxes & fees
Feb 27 - Feb 28
Hotel Pommier Indianola

Hampton Inn & Suites Altoona-Des Moines

Hampton Inn & Suites Altoona-Des Moines
2.5 star property
18.8 km from Greater South Side
9.2 out of 10, Wonderful, (685 reviews)
"Very nice hotel, was a great stay!"
United States
Kelly
The price is ₩130,454
₩146,108 total
includes taxes & fees
Mar 1 - Mar 2
Hampton Inn & Suites Altoona-Des Moines

Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills, 6.2 km from Greater South Side
9.4 out of 10, Exceptional, (1,180 reviews)
"Very nice, comfortable accommodations. Would definitely stay again. "
United States
JoAnn
The price is ₩128,718
₩144,164 total
includes taxes & fees
Feb 24 - Feb 25
Baymont by Wyndham Des Moines Airport

Wildwood Lodge

Wildwood Lodge
3.0 star property
12.8 km from Greater South Side
9.6 out of 10, Exceptional, (1,230 reviews)
"Friendly staff, comfortable rooms and good breakfast. "
United States
Rachel
The price is ₩146,290
₩163,845 total
includes taxes & fees
Feb 24 - Feb 25
Wildwood Lodge

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA
3.0 star property
18 km from Greater South Side
9.2 out of 10, Wonderful, (1,001 reviews)
"Great room, quiet, courteous staff."
United States
Bruce
The price is ₩113,272
₩126,866 total
includes taxes & fees
Mar 1 - Mar 2
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA
2.0 star property
15.3 km from Greater South Side
7.8 out of 10, Good, (760 reviews)
"Nice clean room, friendly staff. "
United States
Cheryl
The price is ₩59,051
₩66,138 total
includes taxes & fees
Feb 25 - Feb 26
Motel 6 West Des Moines, IA

Econo Lodge Ankeny - Des Moines

Econo Lodge Ankeny - Des Moines
2.0 star property
17.7 km from Greater South Side
8.2 out of 10, Very Good, (774 reviews)
"Love the staff! Clean! Nice breakfast bar! "
United States
Tori
The price is ₩76,218
₩85,364 total
includes taxes & fees
Feb 25 - Feb 26
Econo Lodge Ankeny - Des Moines

Aloft Waukee

Aloft Waukee
3.0 star property
18.7 km from Greater South Side
9.0 out of 10, Wonderful, (186 reviews)
"Nice room, comfortable bed, great staff"
United States
Chris
The price is ₩141,734
₩158,742 total
includes taxes & fees
Mar 1 - Mar 2
Aloft Waukee

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG
2.5 star property
14.8 km from Greater South Side
9.2 out of 10, Wonderful, (1,001 reviews)
"Friendly staff, great location, beds could be better. "
United States
Shelley
The price is ₩131,900
₩147,728 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites West Des Moines - Jordan Creek by IHG

Best Western Premier Ankeny Hotel

Best Western Premier Ankeny Hotel
3.0 star property
17.9 km from Greater South Side
9.0 out of 10, Wonderful, (846 reviews)
"Clean, super friendly staff, and great location. "
United States
Darlene
The price is ₩114,545
₩128,290 total
includes taxes & fees
Feb 24 - Feb 25
Best Western Premier Ankeny Hotel

Quality Inn Indianola

Quality Inn Indianola
2.5 star property
20.3 km from Greater South Side
7.6 out of 10, Good, (524 reviews)
"Great as usual "
United States
Tracey
The price is ₩99,026
₩110,909 total
includes taxes & fees
Mar 24 - Mar 25
Quality Inn Indianola
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Greater South Side

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Reception
Hampton Inn Des Moines-Airport
2.5 star property
8.8
Excellent
1,003 reviews
View
Desk, iron/ironing board, free cribs/infant beds, rollaway beds
Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
8.6
Excellent
1,764 reviews
View
Property amenity
Holiday Inn Des Moines-Airport/Conf Center by IHG
3.0 star property
8.2
Very Good
622 reviews
View
Reception
AmericInn by Wyndham Des Moines Airport
2.5 star property
7.8
Good
1,003 reviews
View
Free daily buffet breakfast
Quality Inn & Suites Des Moines Airport
2.5 star property
7.4
Good
1,004 reviews
View

Where to stay in Greater South Side

Find the best Greater South Side areas and neighborhoods for the activities you enjoy most.

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.

Historic East Village

Directly east of Downtown Des Moines, this nationally recognized historic district boasts the Iowa State Capitol complex, State of Iowa Historical Museum, and Des Moines Botanical Gardens. Explore eateries, boutique shops, and loft-style housing in its charming structures.

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.

Western Gateway

While visiting Western Gateway, you might make a stop by sights like John and Mary Pappajohn Sculpture Park and Pappajohn Sculpture Park.

Top Greater South Side Hotel Reviews

Frequently asked questions

What's it like in Greater South Side?
Travelers are sure to enjoy a stay in Des Moines's Greater South Side neighborhood. Consider a visit to Gray's Lake Park as part of your Greater South Side travel plans.
What's a favorite place to stay in Greater South Side?
Based on Expedia customer reviews, Days Inn & Suites by Wyndham Des Moines Airport is the highest ranked property in Greater South Side. This hotel offers free breakfast and an indoor pool. Other favorite options in the area include Hampton Inn Des Moines-Airport and AmericInn by Wyndham Des Moines Airport.
How many hotels will I be able to find in Greater South Side?
With 13 Expedia hotels and other accommodations in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.
If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Greater South Side.
Where can I learn more about changing or cancelling my trip to Greater South Side?
For more information about changing or cancelling your trip to Greater South Side, head over to our customer service page.
What is there to do around this Des Moines neighborhood?
Gray's Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.